Purpose The purpose of this study is to evaluate the treatment results and adverse drug effects for 14 dogs receiving a new paclitaxel preparat named Paccal vet. The evaluated dogs are chosen to enter a pharmacogenomical study. Therefore, this paper intends to give an introduction to pharmacogenomics. Finally this study also aims at finding the homologue genesequenses in dogs to seven genes that are important for metabolism of paclitaxel in humans. Materials and metods The dogs went through 2-4 cycles of paclitaxel treatment, they received a new water-soluble formula named Paccal vet, at dosages of 100-150mg/m2. Treatment results and adverse effects are listed for each dog in table 1.

The current situation for Swedish grain farmers facing a situation with decreasing profitability makes it necessary for the farmers to find ways of increasing the margins in their grain growing. Decreasing profitabilities along with Lantmännens closing of grain elevators contribute to the necessity for farmers to invest in grain storing and drying at the farm. By investing in capacity for drying and storage of grain on the farm it is possible to recieve a higher price on the grain sold due to the possibility to sell when the price is higher compared to the harvesting season. An investment in grain drying and storage with a relatively low investment cost that recently has appeared on the Swedish market is the grain stir drying system. This study contains a comparison of an investment in a grain stir drying system where the grain is dried and stored in the same silo and a conventional drying and storage system.

I detta tvärvetenskapliga arbete studeras från den matematiska sidan tre klassiska populationsmodeller: Malthus tillväxtmodell, Verhulsts logistiska modell och Lotka-Volterras jägarebytesmodell. De klassiska modellerna jämförs med stokastiska. De stokastiska modeller som studeras är födelsedödsprocesser och deras diffusionsapproximation. Jämförelse görs med medelvärdesbildade simuleringar.Det krävs många simuleringar för att kunna genomföra jämförelserna. Dessa simuleringar måste utföras i datormiljö och det är här den datalogiska aspekten av arbetet kommer in.

It today's global world we live in the media have started to examine businesses more and more. In addition consumers are expecting more from products, because they are well informed. This means that companies need to market themselves effectively, to convince and get across their message to their customers. Marketing is an extensive process in which different factors must be taken into account. A company must know what the coustomer needs in order to get through to them.

The use of fossil fuels such as coal and gas are a contributor to the global warming. The climate change is a worldwide problem with far reaching consequences that is believed to be very expensive. The United Nations has been introducing a framework convention on climate change. One component of the convention is the Kyoto protocol. The protocol is obligating the developed countries to decrease their emissions of greenhouse gases by 5.2 percent during the time period 2008-2012.

It today's global world we live in the media have started to examine businesses more and more. In addition consumers are expecting more from products, because they are well informed. This means that companies need to market themselves effectively, to convince and get across their message to their customers. Marketing is an extensive process in which different factors must be taken into account. A company must know what the coustomer needs in order to get through to them.

Bakgrund: Det finns en rad olika faktorer som påverkar produktutvecklingsprocessen vid ett företag. Isaberg Rapid AB utvecklar, tillverkar och marknadsför en rad produkter inom tre olika produktområden; kontor, verktyg och OEM. Denna studie fokuserar på produktutvecklingsprocesserna inom divisionen för kontorsprodukterna vilken kanske är den mest konkurrentutsatta på företaget. Produkterna som tillhandahålls av divisionen är under hårt tryck från konkurrenter på en global basis och snabba och effektiva produktsläpp är av yttersta vikt för att hävda sig på marknaden. De olika aktiviteterna omkring produktutveckling i kombination med de snabba förändringarna av företagets marknadssituation med nya kundgrupper och ökande konkurrens, har lett fram till vissa specifika ofrånkomliga faktorer som har en stor inverkan på produktutvecklingens effektivitet.

The transformation within the swedish infrastructure has been a slow process from thebeginning of time. For almost a decade, the traditional form of contracting regardingbuildings and foremost infrastructure has evolved contracting involving the owner to definethe outcome of the product, regardless involvement from the supposed contractor. As forthe swedish market, the traditional design-bid-build (DBB) have been the primary choice ofcontracting. Although changes have been made over time regarding contracting formswithin the road administration, the railway sector has not improved or justified changesregarding choice of contracting, they have conducted same contracting relationshipsbetween them and the contractor.This bachelor thesis, conducted at the Swedish railway administration with supervision ofprofessor Kristian Widén at Lunds University, explores the forces behind the new era ofcontracting within the railway administration. This bachelor thesis focuses mainly oncontracting regarding design-build-operate-main (DBOM), the new contracting formulabetween the owner and the contractor.

Syfte: År 2005 infördes en ny lag, att företagen som gjorde avsättningar till periodiseringsfonder var tvungna att beskatta en schablonintäkt som erhölls från de gjorda avsättningarna. Problemet som uppsatsen berör är huruvida användandet av överavskrivningar hade förändrats efter att lagen tillkom för periodiseringsfonder jämfört med tidigare. Dessutom fokuserades det också på vilka konsekvenser obeskattade reserver har fått före och efter att lagen trädde i kraft. Syftet med examensarbetet är att kartlägga hur företagens vanor kring avskrivningar över plan förändrades efter införandet av schablonintäkten på periodiseringsfonder, och om överavskrivningar kan anses som ett substitut till periodiseringsfonder istället för ett komplement. Metod: En undersökning gjordes på företagen som är listade på börslistan ?large cap?.

The transformation within the swedish infrastructure has been a slow process from thebeginning of time. For almost a decade, the traditional form of contracting regardingbuildings and foremost infrastructure has evolved contracting involving the owner to definethe outcome of the product, regardless involvement from the supposed contractor. As forthe swedish market, the traditional design-bid-build (DBB) have been the primary choice ofcontracting. Although changes have been made over time regarding contracting formswithin the road administration, the railway sector has not improved or justified changesregarding choice of contracting, they have conducted same contracting relationshipsbetween them and the contractor.This bachelor thesis, conducted at the Swedish railway administration with supervision ofprofessor Kristian Widén at Lunds University, explores the forces behind the new era ofcontracting within the railway administration. This bachelor thesis focuses mainly oncontracting regarding design-build-operate-main (DBOM), the new contracting formulabetween the owner and the contractor.

The transformation within the swedish infrastructure has been a slow process from thebeginning of time. For almost a decade, the traditional form of contracting regardingbuildings and foremost infrastructure has evolved contracting involving the owner to definethe outcome of the product, regardless involvement from the supposed contractor. As forthe swedish market, the traditional design-bid-build (DBB) have been the primary choice ofcontracting. Although changes have been made over time regarding contracting formswithin the road administration, the railway sector has not improved or justified changesregarding choice of contracting, they have conducted same contracting relationshipsbetween them and the contractor.This bachelor thesis, conducted at the Swedish railway administration with supervision ofprofessor Kristian Widén at Lunds University, explores the forces behind the new era ofcontracting within the railway administration. This bachelor thesis focuses mainly oncontracting regarding design-build-operate-main (DBOM), the new contracting formulabetween the owner and the contractor.

Husqvarna AB operates two warehouses located in the area of Jönköping. The most important task is to manage the large volume fluctuations during the peak season. DHL Exel Supply Chain (DESC) run the warehouses and the domestic transportations is outsourced to DHL Express. A number of forwarder agents are responsible for distributing the export gods. In the present situation a bottleneck occurs at the warehouse loading section, and the consequence is fulfill the time of delivery for all customer orders.

The insurance industryis challengedby major changesthrough internationalizationand thusgrowingcompetitionwithmore optionsand greater availabilityfor customers.Solvency II, a new regulatoryframework and anew standard forinsurance companies,is therefore implemented in a steptowardsa more competitive Europeaninsurancemarket. Solvency II will result in extensive structural changes for many insurance companies. Newstandards andinternal models must also be implemented by the companies. Solvency IIhasa tightening effect on thesolvency capital requirements forinsurance companies. At the same time it also leads tomajor changesandincreased demandon risk management andinternal control, alongside with demands fordisclosure of informationto the market.

The sludgebark and to a certain extent the bark were until a decade ago waste products without any economic value that were thrown away. A number of environmental laws and increcing energy prices have improved the prerequisites for increasing the use of these materials. At Seskarö sawmill they burn the sludgebark and a great deal of the bark in the sawmill furnace. The sludgebark has a number of disadvantages compared to bark during burning. The sludgebark is often wet which means the energy net from burning often gets low.

The transformation within the swedish infrastructure has been a slow process from thebeginning of time. For almost a decade, the traditional form of contracting regardingbuildings and foremost infrastructure has evolved contracting involving the owner to definethe outcome of the product, regardless involvement from the supposed contractor. As forthe swedish market, the traditional design-bid-build (DBB) have been the primary choice ofcontracting. Although changes have been made over time regarding contracting formswithin the road administration, the railway sector has not improved or justified changesregarding choice of contracting, they have conducted same contracting relationshipsbetween them and the contractor.This bachelor thesis, conducted at the Swedish railway administration with supervision ofprofessor Kristian Widén at Lunds University, explores the forces behind the new era ofcontracting within the railway administration. This bachelor thesis focuses mainly oncontracting regarding design-build-operate-main (DBOM), the new contracting formulabetween the owner and the contractor.