Determination of serum thymidine kinase 1 (TK-1) activity is used as a tumour marker in both human and veterinary medicine. TK-1 is an intracellular enzyme involved in a salvage pathway of DNA synthesis. The expression of TK-1 is cell cycle dependent and the activity increases markedly after the G1 to S transition in the cell cycle and then declines rapidly in G2. The pronounced proliferative activity in tumour cells result in a higher TK-1 enzyme activity within the cell. The fact that the increased TK-1 activity can be measured in serum makes TK-1 a useful marker in diagnostics of neoplastic diseases and it provides information regarding prognosis and treatment effectiveness. In human medicine a radioactive based test is used to determine the TK-1 serum activity.

This essay examines a presupposed correlation between the way one look upon values and the way one look upon the will of the people in a theoretical democratic context. The more specific purpose is to test the following hypothesis: There is a reversed connection between the way one look upon values and the way one look upon the will of the people in a theoretical democratic context, that is; a strong claim of values give reason to a limited conception of the will of the people and a weak claim of values gives reason for a more unlimited conception of the will of the people.In order to test the hypothesis I examine three different conceptions of democracy, these are: pluralist democracy, deliberative democracy and constitutional democracy. I analyze the way they look upon values, there view of the will of the people and finally if there is a connection between the way they look upon values and the will of the people. Values should be understood in a metaethical context. In other words it is not values in the ?common? meaning, instead its how val-ues in them selves should be understood, and even more relevant, what we mean when we ex-press values.My conclusions are, first and foremost, that there is a correlation between the will of the people and values, according to the formulation of the hypothesis.

The usage of location in mobile applications is becoming more explored as a field, but the ability to implement location-specific data has often been limited and the applications mainly focusing on having information location liked. This thesis aims to explore how to make a mobile application that lets users share and take part of each other?s memories. As well as finding an appropriate balance between location based and location linked messaging..

The aim of this Master thesis is to delineate the ideology behind the public library politics in Gothenburg, during 1945-50. The study is an archive survey. To be able to account for the public library politics in Gothenburg during the period, the author has studied documents in the archive of the public library board in Gothenburg. The description of the politics is the source for the research papers analysis. The thesis principal issue, is on what ideological basis the public library politics has been formulated in Gothenburg, during the period of interest? The concept of ideology is defined as a coherent system of norms and values.

Culture is seen as an abstract phenomenon, not easily defined. It is cathegorized as something that affects every person, though it is seldom described how. This study adress how culture, in the form of basic assumptions and accepted behaviors and ways to think affected how young coaches formed their leadership under the influence of their organization. The possible implications for the importance of knowing about ones culture in an organization affect both the recruitment process in organizations and what the organization stands for and what is conveyed through values and ways to act in the organization. The purpose of this study was, through the use of semi-structured interviews with young coaches and organizational leaders and a review of policys, to get the perspective and experiences of young coaches regarding cultural influence on their leadership.

With the collapse of the Soviet Union and the 9/11 attacks, the landscape of the freedom of religion has changed. The issues now facing freedom of religion varies greatly from the issues that the drafters of the universal declaration of human rights faced after World War II.In the light of the new issues that States face in the intersection of religion and societal interest, scholars have criticized the European Court of Human Rights to give too much leeway to the States in determining how the human rights should be implemented, by using the doctrine of margin of appreciation. Critics of the margin of appreciation claim that it is based on culture relativism and that the doctrine undermines the universality of the human rights. In order to decide if the margin of appreciation has indeed led to a relativization of the human rights I compared it to the jurisprudence of the UN Human Rights Committee and its use of the Syracusa principles. My conclusion is that the jurisprudence of the European Court of Human Rights cannot be considered to be based on culture relativism.

Crisis communication can make a crisis turn into a double crisis. The purpose of the thesis is to analyze by which rhetorical means a double crisis can occur. With the Swedish zoo Parken Zoo as a specific example, this essay examines the crisis communication during the crises that started with the tv-show Kalla fakta. The tv-show revealed that Parken Zoo killed and slaughtered endangered and sacred animals. When asked about the specific animals, the head of the zoo gave different answers ? which contrasted with former employees testimony.

60 million years ago the horse was the size of a small dog, and walked on four toes. Today it can weigh up to 500-1000 kg and has evolved to walking on only one phalanx. The anatomy of the horses? legs and hooves allow them to run at high speeds, and at the same time enables them to bear the extremely high concussions applied to the foot at high speeds or jumps. Every horse owner has his or her own opinion on how to manage their horses? hooves, and whether the horse should be shod or unshod. The knowledge, commitment and attention of the owner determine the quality of the hoof care, but also the time between the arising of symptoms of abnormalities of the hoof until care is sought with a farrier or veterinarian. New laws will be applied at the beginning of 2015 which bring on changes in authorization for farriers.

Children with cleft lip and palate (CLP) and children with specific language impairment (SLI) may be affected emotionally and psychosocially by their disorders. Thus, it is important to investigate the psychosocial risk factors that these children are exposed to. The aim of this study was to examine how parents assess the emotional and psychosocial well-being of children with CLP and children with SLI, and if the two parental groups differ in their assessments using the standardized instrument Child Behaviour Checklist (CBCL). Participants in the study were the parents of ten children with unilateral and bilateral CLP between ages 6;7-9;0 (mean age 7;5) and the parents of 13 children between ages 6;4-8;8 (mean age 7;3) who are attending preschools and schools for children with SLI. These parents were asked to complete the questionnaires CBCL and Child Health Questionnaire (CHQ). The children with CLP had lower scores than the children with SLI in all domains of the CBCL, indicating that these children with CLP had better emotional and psychosocial well-being.

This diploma work has been carried out in collaboration with the building contractor Sh Bygg Fastighetsutveckling AB in Uppsala with the intention to investigate how the height of a building affects various energy aspects such as transmission losses, infiltration, and the specific energy usage. Three different reference objects have been studied. The reference objects have been simulated for four different heights in the calculation program VIP-Energy.The results show that an increase in floor number can lead to both advantages and disadvantages. As the number of floors increases, transmission losses per square meter floor area decreases. However, as the height of the building increases, the reduction rate decreases.

In the present study, the institutional discourse in health care was examined, focusing onspeech therapists and occupational therapists in interaction with a common patient withaphasia. The purpose of the present study was to identify common communication strategiesused in the professional conversation between a speech therapist and a patient and between anoccupational therapist and the same patient. Specific research questions were: Whatcommunicative strategies are used in interaction between a speech therapist and a patient withaphasia and between the occupational therapist and the same patient? Are theredifferences/similarities between how speech therapists and occupational therapists interactwith patients with aphasia?Six people in total, two patients in interaction with a speech therapist and an occupationaltherapist respectively, were recorded during treatment sessions of each profession. Generaland specific aspects of the institutional interaction were then analysed according to principlesof conversation analysis.Similarities in the use of closed questions as a strategy to increase the effectiveness ininteraction could be seen between the two different professions studied.

In order to convince, one must know which arguments are most suitable for the specific situation. But even if you think you know how others will react to your arguments, you may be wrong. Therefore, the purpose of this paper is to find out a way of examining to what extent informative text take account to the subjective views of their addressees. The theoretical framework is Blitzer's theory of the rhetorical situation, pragmatic theory of speech acts and their presuppositions, Burk´s theory of consubstantiality and phenomenographic theory of subjective perceptions. Methodologically, phenomenography has also been used as a guideline for selecting informants, collecting data and processing the interviews.

Culture is seen as an abstract phenomenon, not easily defined. It is cathegorized as something that affects every person, though it is seldom described how. This study adress how culture, in the form of basic assumptions and accepted behaviors and ways to think affected how young coaches formed their leadership under the influence of their organization. The possible implications for the importance of knowing about ones culture in an organization affect both the recruitment process in organizations and what the organization stands for and what is conveyed through values and ways to act in the organization. The purpose of this study was, through the use of semi-structured interviews with young coaches and organizational leaders and a review of policys, to get the perspective and experiences of young coaches regarding cultural influence on their leadership.

This paper aims to apply a specific architectural theory onto Lund City Library in order to achieve a better understanding of how the physical concept of the library is affecting our knowledge and our production of meaning; and furthermore how it suggests a certain form of usage. This paper discusses the ways in which architecture is affecting us when we use the library. The paper attempts to answer the following question: ? Which one of Koch?s spatial structures could apply to Lund City Library, and in which ways could this spatial structure be a producer of meaning? The specific architectonical theory used is developed by Daniel Koch in his paper Spatial Systems as Producers of Meaning: the Idea of Knowledge in Three Public Libraries. This theory is the method of the paper as well.

The aim of this study is to examine how preschools contribute to the forming of identity in children, with a specific focus on the quiet and socially withdrawn child. How do the teachers describe the quiet child and the socially withdrawn child? Are there any opportunities for children to be quiet/withdrawn in preschools? These questions have also been analysed from a gender perspective. The method chosen is qualitative method. Nine preschool teachers from two Swedish preschools have been interviewed.