Haemophilia is an inherited disease which causes increased bleeding due to defect clotting factors VIII and/or IX. There are two forms of haemophilia, A and B, which both are X-linked and due to mutations of the genes of factor VIII and factor IX respectively. This study focuses on Haemophilia A and thereby factor VIII.The drugs that are available on the Swedish market today for patients with haemophilia A include Factor VIII(FVIII), which has been purified from human plasma and recombinant factor VIII(rFVIII). The main goal of this study is to gain a better understanding of the effects of treatment of haemophilia A with either purified plasma factor VIII or recombinant factor VIII on reducing or preventing bleeding and on side effects.  The study was designed as a literature review and searches were carried out in PubMed at the Linnaeus University library.  The criteria for selection of articles were: patients with haemophilia, treatment with plasma derived and/or recombinant factor VIII as well as clinical studies.

This theory consuming thesis is concerned with why Iran's uranium enrichment has become a security issue, and will focus on the five most important and involved actors: China, Russia, Iran, the US and the UN. I will do this by using instruments of analysis such as securitization and strategic analysis. With these instruments I will examine different factors, such as deterrence, the action-reaction model and armament. Since, according to my opinion, security matters include more sectors than military I will also examine the political, societal and economic sectors. China and Russia have acted differently compared to the US in this matter and this thesis will highlight the factors that can explain the different actions made by these countries.

Fusobacterium necrophorum är en gramnegativ anaerob bakterie som grupperas i ss. necrophorum och ss. funduliforme. Fusobacterium necrophorum ss. funduliforme har på senare tid misstänkts kunna spela en roll vid vanligare svalginfektioner såsom halsfluss.

In the beginning of the nineties there was a change in how the voluntary sector was perceived, and the significance of their work became reevaluated and more acknowledged. As a result, this sector gained a new and higher interest. The changes and downsizing in the welfare state with economic crises, due to political cutback, made the politicians look fore new solutions. One solution is to encourage cooperation between the public sector and the voluntary sector in order to handle the different needs of individuals.Uppsala community and the voluntary sector are working closely together within a project called ?God Livsmiljö?.

Bakgrund: Övervikt och fetma bland barn är en av de största folkhälosutmaningarna på 2000-talet och sprider sig som en epidemi i värlfärdsländer. Preventivt hälsoarbete ger en möjlighet att identifiera tidig övervikt och kunna sätta in åtgärder som hälsosamtal och rådgivande samtal i tid. Skolsköterskan har en viktig roll i att upptäcka övervikt och fetma hos barn i lågstadiet. Tidigare forskning har visat att föräldrarnas inställning och familjens livsstil har en stor inverkan på barnets övervikt. Syfte: Styftet med studien var att belysa skolsköterskors erfarenheter av föräldrars reaktioner vid samtal om barnets övervikt eller fetma i lågstadiet.

Syftet med denna studie var att undersöka om träning av exekutiva funktioner kan påverka den intra-individuella variabiliteten (IIV) i reaktionstid hos unga vuxna och äldre. De 29 yngre och 30 äldre deltagarna i studien delades upp i två grupper, en träningsgrupp som gick igenom 15 sessioner av träning i exekutiv funktion och en kontrollgrupp som endast deltog vid pre- och posttestning. I träningsbatteriet tränades de exekutiva funktionerna uppdatering, skiftning och inhibering i enlighet med det teoretiska ramverk om exekutiv funktion som skapats av Miyake (2000). I studiens pre- och postmätningar användes reaktionstidsdata från tre tester: Serial Reaction Time (SRT), Flanker och Alternating Runs. Dessa tester skiljde sig från de som användes i träningsbatteriet.

Agile as an idea was created in 2001 through the Agile Manifesto with focus on social relationships, communication and flexibility. This was a reaction to the traditional, hierarchical organization with the goal of restoring balance within organizations in the IT business. Today we can see a transit of Agile from the IT-industry to other industries and areas, such as HRM.There is a challenge in attempting to traditionally control a social idea such as Agile, and there is a lack of empirical studies of the organizational context and its effect on the interpretation of Agile in practice. This study is an attempt to connect Agile to the science of business administration.The purpose with this study is therefore to research the organizational contexts effects on the interpretation of Agile in practice, within IT and HRM. Where Agile is established or well known.To fulfill our purpose we chose social constructivism as our scientifically approach, and conducted 12 in-depth interviews.

Neuroleptikamedicinering är förenat med en stark biverkningsprofil där sexuella biverkningar hör till de vanligt förekommande. Sexuella biverkningar uppmärksammas inte i forskning i samma utsträckning som andra biverkningar, än mindre för kvinnor i jämförelse med män. Fokus ligger på viktuppgång och dess effekter. Forskning kring sexuella biverkningar vid neuroleptikabehandling och dess påverkan på personers adherence är bristfällig. Syftet: Syftet är att i en pilotstudie undersöka hur biverkningsprofilen på depåneuroleptika med fokus på sexuella biverkningar inverkar på kvinnors inställning till medicinering.Metod: Datainsamlingen gjordes i form av en enkätundersökning på personer som erhåller depå-neuroleptika vid en psykosmottagning i Västra Götaland.

The purpose of this study is to examine how the identity of teenagers is affected by the loss of a parent as well as what coping strategies support identity development. The reactions the teenagers exhibit, in such circumstances, will also be examined. To accomplish this,  a theory package was created, comprising theories in developmental psychology, identity work, coping and theory of grief reactions of children and teenagers. This package provided a broad perspective, which facilitated the analysis. Furthermore, it made it easier to address the purpose and the issue of the analysis.

Obesity and overweight are today classified as one of the largest epidemics in the Western world and is threaten a large part of the population. As a reaction to this a major health trend has emerged in recent decades. Every day consumers are exposed to information from the media about what is healthy or unhealthy to eat and the recommendations change frequently.There is great interest in healthy food on the Swedish food market, but still healthy foods only represents a small proportion of the total food sales. The essay examines the gap between the current and potential demand for healthy food and if it can be explained by any of the following factors: lack of information, price, taste or cognitive behavioral.To study these questions a quantitative method have been used and 213 questionnaires were collected. The intention is to draw general conclusions about the entire population.

Blood samples from 44 clinically healthy cats were analysed for the presence of antibodies to Chlamydophila felis. As we wanted to investigate if the antibody titre of clinically healthy cats correlates to shedding of chlamydia, conjunctival and vaginal or preputial swabs respectively, were taken and analysed with rtPCR (real-time polymerase chain reaction) for the presence of chlamydia DNA. Furthermore, to investigate possible epidemiological factors connected with asymptomatic cats infected with chlamydia and to see if there were any indications that chlamydiosis can cause reproductive problems, the owners of the cats were asked questions regarding this. Sixty-one per cent (27 of 44) of the cats were seropositive. Three of these (11 %) had the highest antibody titre (1:1600).

The world is in a stage of climate crisis where the average temperature is rising, with consequences such as, melting ice sheets, increasing sea levels, and floods. The climate panel of the UN, IPCC, has stated that this is a reaction of anthropogenic emissions of greenhouse gases. The most important gas is carbon dioxide, which contributes with 80 per cent to the on going climate crisis.The increasing emissions of carbon dioxide are connected to human consumption patterns. This puts pressure on the earth, as humans demand more and more resources. Today the earth needs one and a half year to regenerate the resources humans? demand of it, by the year 2030 we will need two planets in order to cope with this increasing demand of resources.At a global level it is established that richer countries have a stronger consumption pattern than poorer, and thus generate higher levels of carbon dioxide emissions.

Powder Metal (PM) gears are machine element components which operate under the same principle as conventional gears, but, due to their intrinsic material characteristic need to be designed slightly different, and its manufacturing process offers advantages previously unobtainable by conventional steel gear manufacturing methods. The use of PM in similar applications, such as synchronous hubs, makes them a suitable candidate for production in such material. The current master thesis work focuses on gear design using PM by utilizing finite element method (FEM) to reduce weight and inertia taking into account root bending strength and tooth deflection.First a topological optimization is used to determine feasible candidates for different web designs which have as objective to reduce volume, similar topologies were shown during different loading conditions; and hence, this topology was chosen as a suitable candidate. A shape optimization of the topological candidate was performed having as state variables root bending strength, independent for compressive and tensile side of the tooth loading; and tooth deflection, which in concept can be correlated to static transmission error (TE).Another aspect in this thesis analysed is the possibility to incorporate non-trochoid root geometry, a trochoid root is always present when machining with a hob, into the gear root and hence reduce the stress concentration here. Due to the use of PM, a non-symmetric optimized root can be achieved and hence be optimizing compression and tension.Results showed significantly lower inertia, for example certain results showed 40% reduced when compared to solid gear, with adverse effects as increase in tooth deformation and increase in maximum principal stress.

In this paper the authors examine three questions: 1) Is stealth marketing messages posing as status updates on Facebook a more effective way of advertising than traditional web banners? 2) What impact has learning about stealth marketing practices in social media on consumer attitude and post purchase behaviour? And finally 3) Will different generations respond differently to these questions?Our findings show that stealth marketing in social media is not more effective than traditional web banners. Furthermore, the result indicates that when consumers find out about stealth marketing practices it will have a negative impact on future purchase intensions and brand image. Most consumers will also have strong feelings of being deceived, which could instigate harmful post purchase behaviour such as negative word-of-mouth and possibly, based on some earlier cases, boycotts.The result of our research shows that the brand perceptions and future purchase intentions of Generation Y, persons between 18 and 30 years of age, are affected in a less negative way than the brand perceptions and future purchase intentions of older generations when finding out about stealth marketing practices in social media. However Generation Y:s reaction is still negative and they do consider traditional web banners to be more credible than status updates on Facebook.

In today?s computerized society more and more companies choose to utilize new applications that can ease the way of handling the information. For many of us is imperative that the process as efficient as possible if one takes in consideration the size of savings that this new application can bring.The developer of the evaluated system is SYSteam AB Huskvarna and they are the ones that gave us this assignment. The application that we evaluate is SCM (Secure Connection Manager). It is already used today by big companies such as Telia and Ericsson to search for errors in telephone servers placed all over the country.