Clopidogrel is an antiplatelet substance that prevents blood coagulation in the arteries. It is an inactive pro drug that becomes activated after first-pass metabolism by the liver. The active metabolite of clopidogrel is 2-oxoclopidogrel, which is unstable therefore pharmacokinetic data is obtained by measuring the inactive metabolite clopidogrel acid in plasma. Clopidogrel is taken orally in tablet form. The aim of this project was to develop a LC-MS/MS method for quantification of clopidogrel and its metabolite in plasma. The method has been developed by optimizing the sample preparation.

AbstractThe purpose of this theses is to compare three different political groups, The IRA, The Baader-Meinhof group and the Al Qaida, who have all used terroristic methods to achieve their separate goals.By finding out about their history, goals, structures and methods I have made a comparison to see what joins them, what separates them, what originated the birth of their movements and how they can or could proceed with their violent actions to the point that they had actual impact on international politics.It has all been done through a litteraturebased study.My focuse has been on Al Qaida since it's is the only one of the three who is still active today and who, through its cellstructure, represents a new form of global terrorism that may have great influence on the structural patterns of other political groups and criminal organizations in the future.Key words:Al QaidaBaader-MeinhofIRATerrorismCellstructure.

The purpose of this study has been to maintain a deeper understanding of how unestablished, professional musicians can get discovered by the music industry by communication, branding and positioning of their brand at social media.We found that fans have a greater impact on unestablished musicians than we previously thought. They have to create an identity for their brand, keep active on social media and engage their fans. Musical artists must maintain an ongoing dialogue to keep their fanbase, preferably with emotions involved. No fans equals minimum attention from the industry. Uniformity and professionalism is also important, because it evokes seriousness.

Purpose: Our purpose is to examine how ExTe works with values and attitudes and if it has any connection to their success.Research questions: Does attitudes and values have anything to with ExTes success? Does ExTes management see their staff as a resource for development and do they deliberately work with it. Does ExTe follow their written Value book and do they continuously and active work with it?Approach: We have used a deductive way of reasoning and a qualitative study to gather the information needed. We have interviewed four staff members at ExTe.Conclusions: ExTes continuously and deliberately work with values and attitudes do have a meaning for their success.

This study concerns art education, and the importance of creativity in learning. The objective is to examine the use of art education in practice, and the school teacher?s position on this practice.The theoretical basis of the study is rooted in a socio-cultural perspective, and concerns the relationships between theoretical concepts as learning, knowledge and art education.The investigation is qualitative and the main research methods are participant observations and structured interviews.The group studied in this investigation consisted of five active educators, who work at different schools and make use of art-based methods in their daily work.My results show that teachers believe that art education can be used by schools as a gateway to the other subjects. Art is regarded as a form of understanding through which pupils explore their surroundings, challenge their ideas and build skills through interaction with others..

No matter what subject or which grade you are active in, the teachers in Sweden have incommon that they are provided with governing documents that states the guidelines and goalsregarding each subject. Along with these governing documents every teacher has to findmaterial that will be used as the foundation of the teaching. This thesis is a study of howSwedish history teachers define what material they are going to use in their teaching, andwhich the factors are that is affecting these choices. The question whether a child?s ethnicaland cultural background is a factor that affects this choice of material is concerned, as well aswhat is current in Sweden and the world.

Landscape architects has many ways of transforming our cities and landscapes. Traditionally, most attention has been put to visual qualities. Pen and paper are well established as the way to present proposals and to analyse in the landscape architects profession and training. But are we perhaps missing out on other ways of seeing the landscape? The purpose of this paper is to present sound as a tool of transformation. Sound in public spaces has long been treated just as noise and therefore unwanted.

This qualitative review concerns motivation out of a teacher?s perspective. The aim of this study is to illuminate how a few teachers work with motivational work in school and elucidate which traits and competences the teachers consider important for them as motivatiors to possess. The result is based on semi-structured interviews with four active teachers with junior school qualifications. The objective was to learn more about the teacher?s own experiences and opinions regarding the construct of motivation, motivational work and their own role as motivators.

This is a qualitative case study of young womens? experiences of blogging about One Direction on the social media/microblogging platform Tumblr. The aim of this study was to find out what fan blogging is and why fans blog. We did this by creating an account on Tumblr where we invited young women between the ages of 16?29, who had active fan blogs dedicated to One Direction, to answer an open-ended questionnaire.

Event is a phenomenon that lately has become more common, especially within the tourism industry. This essay is a study within human geography and with focus on the meaning and the design of events. The purpose with this essay is to examine and describe the concept of event and to show how events can influence a region. Falkenberg is situated in the county of Halland by the west coast and the sea and because of that a natural tourist destination. The city is a known seaside resort since the end of the nineteenth century.

Det går att kartlägga små skillnader som finns i ledarskapsutövandet mellan en chef i ett tjänsteintensivt- och kunskapsintensivt företag, men samtidigt tenderar ledarskapet att gå mot en och samma utveckling, det vill säga, ett coachande ledarskap. Skillnaderna i första linjens chefskap i de två olika organisationerna, anser vi bero mer på företagsstrukturerna än att de är verksamma i skilda branscher. It is possible to survey small differences in how to practice leadership between a service intensive and a knowledge intensive company. The leadership tends on the other hand to go towards the same development, towards a coaching leadership. We do believe that the differences in the first line managers, in the two separate companies, depend more on the business structures than that they are active in different branches of trade..

Conqueror for Indigo is production treated with an active chemical to maximize the ink adhesion.ArjoWiggins has found that another chemical, the candidate compound, would improve the propertiesof the paper. ArjoWiggins therefore wish to replace the current compound. To strengthenthe patent requirements for ink adhesion needs to be determined. A theory is developed to whychemicals with certain properties maximize the ink adhesion. Experiments are performed but theresults are inaccurate.

In this thesis we examine the relationship between board composition and firm performance in Swedish companies. The selection of companies includes all Swedish limited liability companies, with the exception of micro enterprises, that have been active between the years of 2009-2010. We develop hypotheses based on resource dependence theory, agency theory, and the resource based view, and test these with regression analysis against collected data. Specifically, we examine the effects of board diversity, outside directorships, and CEO duality. Our findings show that none of the theories provide sufficient explanatory power of the relationship between board composition and firm performance, and that further research is required to better understand the role and effects of company boards..

The goal of this project was to create the music video for swedish pop/rockband Antennas? single Youngbloods, from their album Feeling Feline Tonight(2009). The video was made through animation, collages, photography andillustration. The main focus for the video was to create an independent visualstory and to implement an investigation of how different technics for creatingand documenting images and motion result in different interpretations of thecontent. The work was characterized by an active search for contrasts andcontradictions.My approach to the project was to work with a child?s curiosity, but withthe discipline of an adult.

Sleep is essential for all mammals and they all have different sleep patterns. Wild horses normally spend 2-8.5% of a 24-hour period in recumbent position while stabled horses lie down 11-20%. To fulfil the need of rapid eye movement (REM) sleep the horse must lie down with support against the ground for the head. The lying behavior can be affected by external stimuli such as age, food intake, bedding materials and if the horses feel safe or not. This study investigates the lying behavior of horses on different bedding materials; wood shavings and filled rubber mats (HIT SoftBed®).