Clopidogrel is an antiplatelet substance that prevents blood coagulation in the arteries. It is an inactive pro drug that becomes activated after first-pass metabolism by the liver. The active metabolite of clopidogrel is 2-oxoclopidogrel, which is unstable therefore pharmacokinetic data is obtained by measuring the inactive metabolite clopidogrel acid in plasma. Clopidogrel is taken orally in tablet form. The aim of this project was to develop a LC-MS/MS method for quantification of clopidogrel and its metabolite in plasma. The method has been developed by optimizing the sample preparation.

AbstractThe purpose of this theses is to compare three different political groups, The IRA, The Baader-Meinhof group and the Al Qaida, who have all used terroristic methods to achieve their separate goals.By finding out about their history, goals, structures and methods I have made a comparison to see what joins them, what separates them, what originated the birth of their movements and how they can or could proceed with their violent actions to the point that they had actual impact on international politics.It has all been done through a litteraturebased study.My focuse has been on Al Qaida since it's is the only one of the three who is still active today and who, through its cellstructure, represents a new form of global terrorism that may have great influence on the structural patterns of other political groups and criminal organizations in the future.Key words:Al QaidaBaader-MeinhofIRATerrorismCellstructure.

Musculoskeletal disorders (MSD) are common in individuals with computer based work. Thecurrently known risk factors for these disorders is in the literature derived to physical,organizational and individual factors. A recent survey of three working groups at a companyin Stockholm explored that more than 50% of the employees had neck and shoulder problems.Aim: The study aims to create a better understanding for the current musculoskeletalproblems at the company. Such an understanding is created by examining the physical,organizational and individual risk factors in the workplace and the result can provide a goodbasis for intervention proposals.Method: In order to answer the aim of the study the authors chosed to use both qualitativeand quantitative methods of data collection through interviews and questionnaire survey. Theinterview and questionnaire was designed to create both a specific and comprehensive pictureof the physical, organizational and individual risk factors having a bearing effect on theexisting MSD problem.Result: Seven categories were compiled from interviews, which largely deals with the factthat high demands can lead to behaviors that may pose a significant risk for the occurrence ofMSD.

The purpose of this study has been to maintain a deeper understanding of how unestablished, professional musicians can get discovered by the music industry by communication, branding and positioning of their brand at social media.We found that fans have a greater impact on unestablished musicians than we previously thought. They have to create an identity for their brand, keep active on social media and engage their fans. Musical artists must maintain an ongoing dialogue to keep their fanbase, preferably with emotions involved. No fans equals minimum attention from the industry. Uniformity and professionalism is also important, because it evokes seriousness.

The purpose of this study is to analyze which communication strategies andinformation- and communication channels that Gällivare municipality should useunder the urban transformation to communicate with the citizens. The studyconcentrates on the age-groups 16 ? 24, 25 ? 44, 45 ? 64 and people that are 65 yearsand older. This selection has been made as a segmentation of the citizens and is oneof the essay questions which refers to study the channels that each age-groups prefer.The study is a quantitative one and is based on a questionnaire survey directed to thecitizens and it?s 85 people who participated.

Purpose: Our purpose is to examine how ExTe works with values and attitudes and if it has any connection to their success.Research questions: Does attitudes and values have anything to with ExTes success? Does ExTes management see their staff as a resource for development and do they deliberately work with it. Does ExTe follow their written Value book and do they continuously and active work with it?Approach: We have used a deductive way of reasoning and a qualitative study to gather the information needed. We have interviewed four staff members at ExTe.Conclusions: ExTes continuously and deliberately work with values and attitudes do have a meaning for their success.

No matter what subject or which grade you are active in, the teachers in Sweden have incommon that they are provided with governing documents that states the guidelines and goalsregarding each subject. Along with these governing documents every teacher has to findmaterial that will be used as the foundation of the teaching. This thesis is a study of howSwedish history teachers define what material they are going to use in their teaching, andwhich the factors are that is affecting these choices. The question whether a child?s ethnicaland cultural background is a factor that affects this choice of material is concerned, as well aswhat is current in Sweden and the world.

This study concerns art education, and the importance of creativity in learning. The objective is to examine the use of art education in practice, and the school teacher?s position on this practice.The theoretical basis of the study is rooted in a socio-cultural perspective, and concerns the relationships between theoretical concepts as learning, knowledge and art education.The investigation is qualitative and the main research methods are participant observations and structured interviews.The group studied in this investigation consisted of five active educators, who work at different schools and make use of art-based methods in their daily work.My results show that teachers believe that art education can be used by schools as a gateway to the other subjects. Art is regarded as a form of understanding through which pupils explore their surroundings, challenge their ideas and build skills through interaction with others..

Landscape architects has many ways of transforming our cities and landscapes. Traditionally, most attention has been put to visual qualities. Pen and paper are well established as the way to present proposals and to analyse in the landscape architects profession and training. But are we perhaps missing out on other ways of seeing the landscape? The purpose of this paper is to present sound as a tool of transformation. Sound in public spaces has long been treated just as noise and therefore unwanted.

To be able to provide the growing human population with food, the productivity of the animals as well as land use needs to be improved and intensified. Hence, understanding the behavior of animals is crucial both for animal welfare and productivity as well as the management of the cattle. There are many factors affecting the grazing behavior of cattle in tropical conditions, such as human-animal interactions, herd management, breed, season and temperature. The purpose of this study was to investigate the grazing behavior of two tropical cattle breeds, Ankole and Boran cattle. Kenyan Boran belongs to a zebu type of cattle and is preferred to many other breeds due to the higher productive and reproductive capacity and adaptability to tropical conditions.

This qualitative review concerns motivation out of a teacher?s perspective. The aim of this study is to illuminate how a few teachers work with motivational work in school and elucidate which traits and competences the teachers consider important for them as motivatiors to possess. The result is based on semi-structured interviews with four active teachers with junior school qualifications. The objective was to learn more about the teacher?s own experiences and opinions regarding the construct of motivation, motivational work and their own role as motivators.

This is a qualitative case study of young womens? experiences of blogging about One Direction on the social media/microblogging platform Tumblr. The aim of this study was to find out what fan blogging is and why fans blog. We did this by creating an account on Tumblr where we invited young women between the ages of 16?29, who had active fan blogs dedicated to One Direction, to answer an open-ended questionnaire.

Event is a phenomenon that lately has become more common, especially within the tourism industry. This essay is a study within human geography and with focus on the meaning and the design of events. The purpose with this essay is to examine and describe the concept of event and to show how events can influence a region. Falkenberg is situated in the county of Halland by the west coast and the sea and because of that a natural tourist destination. The city is a known seaside resort since the end of the nineteenth century.

Abstrakt Barnen med alkoholmissbrukande föräldrar lever i svåra förhållanden och de är noggranna med att bevara hemligheten om alkoholmissbruket. Barnets liv påverkas mycket negativt och det orsakar destruktiva konsekvenser i barnets framtid. Syftet med studien är att ta reda på hur förälderns alkoholmissbruk påverkar kommunikationen med barnet och hur barnets utveckling påverkas. Syftet besvarades genom öppna frågor till barn till föräldrar med alkoholmissbruk. Deltagarna i studien är fyra barn mellan 14 och 15 år gamla och en mamma till två barn på 11 och 14 år.

Det går att kartlägga små skillnader som finns i ledarskapsutövandet mellan en chef i ett tjänsteintensivt- och kunskapsintensivt företag, men samtidigt tenderar ledarskapet att gå mot en och samma utveckling, det vill säga, ett coachande ledarskap. Skillnaderna i första linjens chefskap i de två olika organisationerna, anser vi bero mer på företagsstrukturerna än att de är verksamma i skilda branscher. It is possible to survey small differences in how to practice leadership between a service intensive and a knowledge intensive company. The leadership tends on the other hand to go towards the same development, towards a coaching leadership. We do believe that the differences in the first line managers, in the two separate companies, depend more on the business structures than that they are active in different branches of trade..