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1597 Uppsatser om Active Pharmaceutical Ingredient - Sida 17 av 107

The screening for novel proteasome inhibitors as a treatment of cancer using IncuCyte FLR and fluorometric microculture cytotoxicity assay.

The problem of finding targeted medicine is a central problem in chemotherapy. From this point of view the ubiquitin-proteasome system is a highly promising object in the pharmaceutical approach. Proteasome plays a critical role in cellular protein degradation, cell cycle and apoptosis regulation.Proteasome inhibitors are substances blocking the actions of proteasome. Cancer cells are more sensitive to inhibition of the ubiquitin-proteasome system than normal cells. Therefore proteasome inhibitors have the potential to be successfully used in the cancer treatment.The study aimed to test various substances to identify possible proteasome inhibitors with the IncuCyteTM FLR image system and fluorometric microculture cytotoxicity assay.

En Djupdykning i Kommunikationsstrategi : om konsten att locka folk till svenska dykvatten

Purpose/Aim: To create a communication strategy for PADI Nordic with the intention of getting Swedish divers, who have been certified abroad, to Swedish dive centers.Material/Method: The study is based on a number of personal interviews conducted with a) divers who are active in Sweden, b) divers who are not active in Sweden and c) representatives from PADI and PADI affiliated dive centers.Main results: The main reason that people who have been certified abroad do not dive in Sweden is that they regard it as being too complicated, too cold, too expensive and with nothing interesting to see. These might partly be misconceptions that can be corrected through a communication strategic effort. The best way to change this perception is by two different forms of communication. One will go from PADI Nordic straight to the divers through an email. This will have the purpose of getting their attention, making diving sound interesting and raise their awareness in preparation for the other part of the process.

Verksamhetsstyrning med fokus på intressenters och medarbetares betydelse : ett fundament för företagens varaktiga framgång?

We would like to gain a more in depth knowledge of whether the modern orientations both within corporate governance and control philosophy lay the foundation for enterprises? more sustainable success. These both modern orientations are increasingly focusing on the importance of enterprises? setting of goals and visions on the basis of stake holders? interests and the employees? more active engagement in and motivation for the goal achievement. Despite these common inherent characteristics, it is not evident from current scientific debate how such integration actually emerges in the control philosophies of the enterprises.

?Man kan inte läsa bara för att man kan tala? : En studie om årskurs ett-elevers föreställningar om läsning och bokval

The aim of the study is to investigate what pupils in grade 1 think about reading aloud, reading alone, the selection of books, and the significance of reading. A subsidiary aimwas to examine the relation between the pupils? experiences of reading in the home andtheir ability to discuss a text they have read. A sidetrack in the study aimed to see whether the pupils? experiences of reading in the home affected their outlook on readingin general.

Miljön kring Dalarnas damfotbollsspelare : Vad påverkar deras möjligheter till utveckling?

2011 Praktik med examensarbete i idrottspedagogik inom Idrottsvetenskapliga programmet, 15 hpSofia Pettersson (2011). Miljön kring Dalarnas damfotbollsspelare ? Vad påverkar deras möjligheter till utveckling? (The environment surrounding female football players in Dalarna, Sweden ? What factors affect their opportunities to develop?) Bachelor Essay in Swedish. Umeå: Umeå university, Department of EducationThe following study investigated the environment in which female football players in the district of Dalarna in Sweden operate. The aim was to identify the elements that affect the players? ability to develop according to their own potential, values and differences.

Skönhetsvård : -En tjänst som hamnar utanför konsumenttjänstlagen ?

AbstractThis essay is about what rights that a consumer has, after it?s been to a beauty-shop getting a treatment somewhere on her body. We were interested to see what kind of regulations that could be useful if a problem occurred after or during treatment. There are several risks with these treatments.The last decade these kinds of treatments have increased, due to people being vain and so aware about there looks. We started to investigate what type of rights the consumer generally has when it?s about a service.

Initial behandling med kortikosteroid vid inandning av retande gaser : en litteraturstudie

AbstractAim: The aim of this study was to investigate if treatment with ?dry needling? in myofascial triggerpoints (MTrPs) in the rotatorcuff muscles may affect impingement symptoms such as pain during provocative tests, shoulder mobility, and function. The research questions were: Does the value of pain change on the Visual Analog Pain Scale (VAS) between before and after treatment? Do the positive provocative tests for impingement change between before and after treatment? Does the active shoulder mobility change between before and after treatment? Does the self-rated function change between before and after treatment?Method: The study was a prospective randomized intervention study and 19 persons with impingement symptoms (mean ± standard deviation; 58 ± 18 years, and shoulder pain duration 3.9 ± 1.6 months) were randomized into two groups. The groups were tested before, directly after and 3 weeks after treatment.

Ålfiskeförbudet : en undersökning av olika aktörer och olika aktörers åsikter på förvaltning, kommunikation och framtiden inom svenskt ålfiske

The first of May 2007, a decision from the Swedish Board of Fisheries about a Swedish prohibition of eel fishery got legal force. This prohibition is one of the most challenged decisions that the Swedish Board of Fisheries has taken. In the town Karlskrona in the southeastern part of Sweden the prohibition has got a lot of attention in local media. Early in the debate, it was clear that the actors active in the archipelago of Karlskrona were against the prohibition. The aim with the master thesis is to investigate different actors' opinions and view of the prohibition of eel fishery, today's management of the resource and how the actors' think that the communication between the actors involved in the management of eel and eel fishery works and what need to be changed to be able to develop a sustainable management of the eel in the future.

Verksamhetsstyrning med fokus på intressenters och medarbetares betydelse - ett fundament för företagens varaktiga framgång?

We would like to gain a more in depth knowledge of whether the modern orientations both within corporate governance and control philosophy lay the foundation for enterprises? more sustainable success. These both modern orientations are increasingly focusing on the importance of enterprises? setting of goals and visions on the basis of stake holders? interests and the employees? more active engagement in and motivation for the goal achievement. Despite these common inherent characteristics, it is not evident from current scientific debate how such integration actually emerges in the control philosophies of the enterprises.

Ny historia? : Lärares uppfattningar och tolkningar om ämnesplanen i historia

This essay aims to examine how three active history teachers in the upper secondary school interprets the new course plan for history in gy11. The essay shows how they discuss and express opinions regarding three main keywords - historical awerness, use of history and source criticism, and finally, how they think they need to change the way they teach..

Fyra forskares informationsförsörjning och bibliotekets roll i denna process : en fallstudie på AstraZeneca R&D i Lund

Information is essential in order for pharmaceutical companies to be successful. This essay focuses on the information provision of pre-clinical scientists at AstraZeneca R&D Lund, and the role of the company library in this process. In semi-structured interviews, four pre-clinical scientists were asked to describe their information provision regarding what type of information they need, how they find it and what sources of information they use. Four librarians from the company library were also interviewed to give their perspective on the information provision of pre-clinical scientist. The study also aimed at comparing the image of the process as described by the scientists themselves and the librarians.

Analys av hur byggnadens höjd påverkar energiförbrukningen i flerbostads- och kontorshus

This diploma work has been carried out in collaboration with the building contractor Sh Bygg Fastighetsutveckling AB in Uppsala with the intention to investigate how the height of a building affects various energy aspects such as transmission losses, infiltration, and the specific energy usage. Three different reference objects have been studied. The reference objects have been simulated for four different heights in the calculation program VIP-Energy.The results show that an increase in floor number can lead to both advantages and disadvantages. As the number of floors increases, transmission losses per square meter floor area decreases. However, as the height of the building increases, the reduction rate decreases.

Träning av motorisk/postural kontroll

Humans and dogs are both mammals. One of the differences between the two species is that man walk on two legs and dogs on four legs. There are also differences in the nerve system between the two species. The human nerve system is supposed to provide opportunity for fine motor tasks- while the nerve system of the dog is more focused on the ability to perform locomotor tasks. Humans need to increase their motor control and postural control when affected by various conditions and diseases.

Energiberäkningar för passivhus

AbstractClimate and environmental issues are of paramount importance. Researchers agreethat we must all contribute to a reduction of gases that contribute to climatechange. Energy consumption must decrease within all sectors and the promotionof renewable sources of energy must be introduced.Each sector should aspire to decrease its energy consumption. Energyconsumption is strongly linked to waste gases that contribute to climate change.Passive houses are a part of the construction industry's methods to attain energyconservation.Passive houses are derived from low energy houses and super insulated houses. Apassive house is intended to obtain heat from the inhabitants and through theiractivities.

Vilka egenskaper anses viktiga vid valet av kandidater till fullmäktige?

The aim of this work is to understand the recruitment of candidates to the local representative assembly in the municipality of Täby. The method used is qualitative interviewing, of a total of eight local politicians in Täby. The theory in which this work rest upon is based on a new-institutionalist perspective. Of great importance is the thoughts of the politicians involved in the recrution process, what do they think were the reasons that controlled the order of priority in the party list among the pool of candidates? Were there any obstacles for minorities in the politics like for example foreigners, women or young people? The study is taking it?s departure from the politicians who candidated in the election of 2002-2006 and the ones which are candidating to the election this coming autumn.In conclusion the aim is to understand the reasons that gives some of the candidates electable places to the assembly, and what the actors themselves think are the conclusive qualities that matters the most.

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