15 uppsatser
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… Itraconazole is only available in therapheutics approved for human use. Pharmacokinetic studies has been performed in humans, dogs, cats and laboratory animals. Although itraconazole has been used tentatively with good effect against fungal infections in horses, no …
klinisk farmakologi
… an analgesic drug for dogs although there are very few studies describing the pharmacokinetics of methadone in this species. In man methadone has a long half-life and there are considerable differences in pharmacokinetics between individuals. The dose interval is lengthened when …
farmakokinetik samt känslighet hos gramnegativa bakterier från föl med septikemi
… determined by liquid chromatography tandem mass spectrometry (LCMSMS). The pharmacokinetic parameters of TMP and SDZ from the foals were compared to published data for adult horses. The pharmacokinetic properties of sulphadiazine were equal to those of adult horses with the …
… intramuscularly have been found. It is therefore essential to investigate the pharmacokinetics for penicillin G sodium following intramuscular injection in horse. The aim of the present study was to examine the pharmacokinetics of penicillin G following intramuscular …
farmakokinetik efter subkutan injektion
… for use in other species are consequently being used without knowing the pharmacokinetics of these drugs in goats. The purpose of this study was to investigate the pharmacokinetics of the opioid butorphanol when given subcutaneously in goats. Subcutaneous administration might …
grundläggande farmakokinetik och påverkan på beteende
… study the opioid buprenorphine was given to 8 clinically healthy goats. The pharmacokinetics and behavioral effects were studied. Injections of buprenorphine, 0.02 mg/kg body weight was given both intramuscularly (i.m.) and intravenously (i.v.) with a cross over design. The …
… Aging brings physical and psychological changes leading to changes in pharmacokinetic and pharmacodynamic features. Drug treatment is becoming increasingly widespread and contributes to the increasing number of interactions and complications for the elderly. The aim of the study …
… metabolite of clopidogrel is 2-oxoclopidogrel, which is unstable therefore pharmacokinetic data is obtained by measuring the inactive metabolite clopidogrel acid in plasma. Clopidogrel is taken orally in tablet form. The aim of this project was to develop a LC-MS/MS method for …
… Serum concentrations of trimethoprim and sulfadiazine were measured and the pharmacokinetics for the substances were studied. The elimination half time (t½) and clearance (ClB) for trimethoprim and sulfadiazine for the foals did not diverge from adult horses. According to these …
… Serum concentrations of trimethoprim and sulfadiazine were measured and the pharmacokinetics for the substances were studied. The elimination half time (t½) and clearance (ClB) for trimethoprim and sulfadiazine for the foals did not diverge from adult horses. According to these …
… Serum concentrations of trimethoprim and sulfadiazine were measured and the pharmacokinetics for the substances were studied. The elimination half time (t½) and clearance (ClB) for trimethoprim and sulfadiazine for the foals did not diverge from adult horses. According to these …
… in horses. Methadone is used in pain management in horses but the full pharmacokinetic picture of methadone is not yet known. The aim of this pilot study was to develop a behaviour protocol and suggest a reliable recording method for use in a larger research project with an aim …
… to investigate and describe the influence of St. John’s wort extract on the pharmacokinetics of the drugs mentioned above and what this pharmacokinetic interaction has for clinical consequences.Seven studies, with different numbers of participants, performed in different …
Opioidplåster avsedda för humant bruk används idag även för smärtlindring av djur eftersom det inte finns några registrerade veterinärmediciniska opioidplåster. För humant bruk finns plåster innehållande fentanyl och buprenorfin. Syftet med litteraturstudien var att granska …
Tramadol är en centralt verkande opioid vars smärtlindrande effekt främst anses bero av två mekanismer. Dels en svag affinitet för ?-receptorn men även en inhiberande effekt på återupptaget av och en stimulerande effekt på den cellulära frisättningen av serotonin och …
