Vilometabolism hos barn och ungdomar med Cerebral Pares
En deskriptiv korrelationsstudie
Cerebral PalsyBasal Metabolic Rate (BMR)Resting Metabolic Rate (RMR)Indirect respiratory calorimetry.Cerebral ParesBasalmetabolism (BMR)Vilometabolism (RMR)Indirekt respiratorisk kalorimetri.
Background: Cerebral Palsy is usually divided into three subgroups: ataxic, spastic and dyskinetic, where children and adolescents can, because of misestimation in nutrition and energy intake, suffer from weight problems.Aim: To compare calculations with equations with the individual's measured RMR in the subgroups, to see if any equation is more suitable. This could be used as a tool to calculate the resting metabolism at times when it is not possible to perform clinical measurements.Method: The RMR has been measured in 37 children and adolescents aged 3-15 years through indirect respiratory calorimetry. Those values have been compared with calculations from five equations. The results were then analyzed in order to find if any equation is better to apply for calculating resting metabolism for each subgroup.Results: The ataxic group was overestimated by 56.5% of the calculated values. WHO/FAO/UNU?s equation indicates a significantly strong correlation between the measured and calculated values (r=0.85, p<0.05). The spastic group was underestimated by 53.3%. There is significance for all equations, however it is a relatively low correlation (r=0.63?0.66, p=0.02?0.03). The dyskinetic group was underestimated by 95%. There was no significant association between clinically measured values and the calculated resting metabolism (r=0.21?0.45, p=0.26?0.61).Conclusion: The equations are not reliable for calculation of energy need for all subgroups. There is a substantial risk of over- and underestimation, therefore awareness of the equations insufficiency is needed. Studies should be performed with additional basic data, and with more equations. Especially equations including further variables that involves the body composition.