Background: Infection with Human Papillomavirus, HPV, is one of the world's most common sexual transmitted infections. The virus causes genital warts (condyloma) but certain virus types can cause cancer. The most common cancer type caused by the virus is cancer of the cervix. Nowadays there is a screening program for women between 23 and 60 years of age where Pap smears of the cervix is taken to discover abnormalities at an early stage. Cervical cancer is very common all over the world and this screening program saves many lives, but not in the less developed countries since the screening program is too expensive.

Feline infectious peritonitis (FIP) is a feline viral disease with high mortality. There is no cure or any effective Vaccine available today. Many questions are yet to be answered about this disease and the immune response in affected cats. The aim of the study is to evaluate two different techniques for the study of cytokine profiles in cats vaccinated with a Vaccine concept against FIPV. More information about the immune response in these cats could give valuable information to better understand the pathogenesis of the disease and the development of an effective Vaccine.

Vaccinology is an ever expanding field. As a member of the veterinary staff it is important to stay up to date with the continuous new scientific data and recommendations that affect the care that our companion animals receive at the veterinary clinic. This paper presents adverse vaccination reactions, their cause, risk factors and suggestions how we can minimize the risk of adverse Vaccine events in dogs. Dog owners in Sweden were allowed to answer a questionnaire about adverse events following vaccination. Lethargy, edema and pruritus were among the most frequently seen adverse effects.

The WT1 gene is a complex gene originally known to suppress cancer in kidneys. Studies of WT1 knockout mice have confirmed the important role of WT1 in the pathogenesis of Wilms? tumour, a tumour which counts for 95% of all childhood renal tumours. In that case the WT1 gene acts as a tumour suppressor gene. Subsequent research has shown that the WT1 gene in many other cases acts as an oncogene, e g in leukemia or lung cancer (even though these cancer forms can emerge as a result of many other aetiological factors).

Purpose: To assess awareness and attitudes regarding HPV, HPV-Vaccines, use of condom and participation in pap-smear screening among high-school students in Uppsala County. The intention was also to investigate if there were any differences between students at theoretical programmes and vocational programmes.Methods: 608 students from seven high-schools in Uppsala County answered a questionnaire covering demographics, awareness and attitudes regarding HPV, HPV-Vaccine, use of condoms and pap-smear tests.Results: A majority of the students had never heard of HPV (86 %, n=521), HPV-Vaccine (94 %, n=537) or the link between HPV and cervical cancer (88 %, n=563). Most respondents had a positive attitude towards HPV-Vaccine (84 %, n=508), but the biggest obstacle was the high cost (37 %, n=227). The students believed that it was less likely that they would use a condom with a new partner if vaccinated (mean=78, SD=26, p<0.001), or if they or their partner used contraceptive pills (mean=62, SD=32, p<0.001) compared to how likely it was that they would use a condom in general with a new partner. The girls rated the probability that they would participate in a pap-smear screening as relatively low if vaccinated (mean=59 SD=27).

Human Papilloma virus (HPV) can lead to cervical cancer, a common form of cancer in Sweden and globally. A Vaccine has been developed for the most carcinogenic strains of HPV. In Sweden it is planned that the Vaccine be included in the public national vaccination program for children. The aim of this study was to illustrate attitudes towards future sexual habits and preventive cervical cancer screening among young women and parents of girls vaccinated against HPV. This study is a part of a larger project where interviews with young women aged 17 to 26 years and parents of girls aged 13 to 17 years compose the foundation.

There's a good adherence to the vaccination of children, about 98% of all two year olds are vaccinated. Despite this, there are cases of whooping cough and measles in Sweden. The purpose of the study was to describe what motivates parents to not vaccinate and reflections and attiudes about vaccinations. The study had a descriptive design with qualitative approach. Eight parents who had chosen not to follow the National Board of Health?s vaccination program or whom had decided to completely abandon, participated in the study.

There's a good adherence to the vaccination of children, about 98% of all two year olds are vaccinated. Despite this, there are cases of whooping cough and measles in Sweden. The purpose of the study was to describe what motivates parents to not vaccinate and reflections and attiudes about vaccinations. The study had a descriptive design with qualitative approach. Eight parents who had chosen not to follow the National Board of Health?s vaccination program or whom had decided to completely abandon, participated in the study.

The Northern Raccoon (Procyon lotor) belongs to the Carnivore-family and is a species endemic to North America. Every year hundreds of orphaned raccoon cubs are admitted into the Wildlife Rehabilitation Center of Minnesota (WRCM), a non-profit organization where all injured or orphaned wild animals are admitted and receive quality health care with the goal of being released out into the wild. The WRCM routinely vaccinate all of the admitted raccoon cubs with a killed feline panleucopenia Vaccine, but despite this there are outbreaks of parvovirus infection every year where up to 50% of the admitted cubs have been euthanized or died. The objective of this study was to determine whether vaccinating the admitted raccoon kits has any significant protective effect to developing clinical parvoviral disease. A single-blinded cohort study was designed with two parallel, independent groups. One group was given a dose of killed feline parvovirus Vaccine at admission, and the other group was not given any vaccination at all. Assignment to the vaccinated or unvaccinated group was on a per-litter basis and done randomly by drawing lots out of a box.

Rabies kills about 55 000 people every year and more than 90% of infected humans are considered getting the disease from dog-bites. To control the disease and eventually eliminate human rabies, the most efficient and economic method is to keep the dog population vaccinated. The objective of this thesis was to evaluate the situation of canine rabies in two urban areas in Lilongwe, Malawi, where canine rabies is enzootic. In each area 200 household-interviews were conducted in September and October 2013. Focal points were awareness of the disease, human incidence as well as vaccination coverage in the dog population.

Bakgrund: Sedan januari 2010 ingår vaccin mot humant papillomvirus i det svenska barnvaccinationsprogrammet. Beslutet att Vaccinera eller inte Vaccinera sina barn kan vara svårt för föräldrar. Syfte: Var att beskriva föräldrars kunskap om och attityd till vaccin mot humant papillomvirus och hur det inverkar på deras beslut att Vaccinera sina barn. Design: Mixed-methods research integrated design. Metod: Beskrivande litteraturstudie.

Alzheimers sjukdom är en smygande neurodegenerativ demenssjukdom som främst drabbar äldre och som karakteriseras av uppkomsten av amyloidplack och neurofibriller i hjärnan. De vanligaste symptomen är demens, kognitiva problem, inbillningar och aggressivitet. Alzheimer förekommer i två olika former, presenil och senil alzheimer. Den fullständiga mekanismen bakom alzheimer är ännu okänd men två proteiner, beta-amyloid och tau, anses ligga bakom orsaken till alzheimer. Ett tredje inblandat protein som man funnit via genetisk analys är apolipoprotein E.

Det finns många olika typer av bromerade flamskyddsmedel. De är alla stabila i miljön men graden av toxicitet och bioackumulering varierar. Att bromerade flamskyddsmedel är endokrinstörande är känt men min hypotes är att de även är neurotoxiska och att de kan orsaka neurologiska störningar hos människa. Människor exponeras för bromerade flamskyddsmedel via damm och föda. Barn och foster som är känsligare än vuxna kan även exponeras via modersmjölk respektive placenta. Barn har högre serumkoncentrationer av bromerade flamskyddsmedel än vuxna.

Many farms in the counties in the south of Sweden have difficulties with diseases spread by ticks; mainly babesiosis and tick-borne fever (TBF) but there are indications that borreliosis ought to be included. All of the tick-borne diseases radically decrease farm profit if the herd is affected. The production of the Vaccine used against babesiosis since the 1920´s, will be discontinued in the near future and in addition to economical reasons it is therefore important to learn more about the diseases above. During the summer and fall of 2002 and 2003, a farm in the island of Gotland was burdened with unusually many cases of bovine babesiosis. In total 43 animals fell ill and one died.

Vaccination as a part of the preventative public health project has for many years been one of the important tasks of the children's health care. The vaccination program has been adjusted to current research and the health situation in the country. Having their children vaccinated is not something obvious for all parents, though. Especially the vaccination against measles, whooping cough and German measles have been questioned. The purpose of this literature study was to investigate the reasons for the resistance to vaccinate and to illuminate the security creating advice of the nurse at the public health centre.