Pyodermi är en hudsjukdom hos hundar som orsakas av Staphylococcus Pseudintermedius (S. Pseudintermedius), tidigare benämdes den S. intermedius. Pyodermi kan ge många olika symptom såsom klåda, håravfall, rodnad, varigt och blodigt exsudat, papler, pustler, sårskorpor och nekrotiserad hud. Ofta finns det bakomliggande orsaker och sjukdomar hos hunden som tillåter stafylokockerna att kolonisera huden. Staphylococcus Pseudintermedius är en Grampositiv kock, den är koagulas-, DNas-, katalas- och ureaspositiv och ger dubbelhemolys på blodagar. Patogenesen vid pyodermi är ännu inte helt kartlagd.

Staphylococcus Pseudintermedius (S. Pseudintermedius) är en opportunist som ingår i hundars normalflora och den bakterie som oftast orsakar pyodermi hos hund. En alltför frikostig användning av antibiotika inom veterinärmedicinen har selekterat fram nya resistenta bakterier som meticillinresistenta S. Pseudintermedius (MRSP). Det är en bakterie som i vissa fall visat sig vara resistent mot alla större antibiotikagrupper som används inom veterinärmedicinen.

The increased frequency of reported Methicillin-resistant Staphylococcus Pseudintermedius (MRSP) is of great concern to small animal healthcare due to limited options of antimicrobial therapy. The aim of this literature study is to investigate 1) characteristics and classification of S. Pseudintermedius, 2) resistance mechanisms and emergence of MRSP, 3) risk factors for selection of MRSP, and 4) clonal distribution around the world. S. Pseudintermedius is a skin and mucosal commensal in healthy dogs and cats, but can cause infections, including pyoderma. Beta-lactam antibiotics inhibit bacterial growth by binding to the penicillin binding protein (PBP), a vital enzyme in the synthesis of the bacterial cell wall.

During the last years, meticillin resistant Staphylococcus Pseudintermedius (MRSP) have caused an increasing number of infections in Swedish dogs. MRSP is resistant against a majority of the antimicrobials available for dogs in Sweden, making it difficult to treat the infection. Our knowledge of the bacterium is limited, making it hard to handle infected dogs in a proper way. The aim of this study was to investigate for how long time dogs, who have an infection caused by MRSP, become carriers of the bacterium. Other factors like treatment with antimicrobials, the correlation between clinical symptoms and carriage, common diagnoses and institutionalization where also looked upon.

Surgical site infections are a recurrent problem in veterinary medicine. A 2-5 % infection rate in clean surgery has been reported. During the last years the increase in methicillin resistant staphylococci has also taken its toll on veterinary medicine, demanding a stricter hygiene and antibiotic regime. The 2008 outbreak of methicillin resistant Staphylococcus aureus (MRSA) at the University animal hospital, Swedish University of Agriculture indicated that that the MRSA problem was now a real, possibly zoonotic problem.Since the first dog, in Sweden, was diagnosed as a carrier of methicillin resistant Staphylococcus Pseudintermedius (MRSP) in a study in 2006, the infection rate by this bacterium has increased. In 2009 (January 1st - December 2nd) the National Veterinary Institute (SVA) has identified 58 samples as MRSP positive.

Chemotherapy is one of the most important methods of treatment available today for the treatment of neoplastic diseases and gives many patients an increased quality of life and a prolonged survival time (McKnight, 2003). The object of this study was to find out more about owners? views on and experiences of chemotherapy of dogs when it comes to for example quality of life, side effects and if they would make the same decision and treats their dog again in the future. A questionnaire was in the spring of 2009 sent out to the owners of 100 dogs that had been treated with chemotherapy for neoplastic diseases at Universitetsdjursjukhuset, Sveriges Lantbruksuniversitet (SLU) in Uppsala between 2002 and 2008. The response rate was 67 %.