In this work we have compiled results from various studies concerning medical conditions that may possibly be avoided by castration and the effects that may occur after castration of the healthy bitch. The work is a literature review but it also includes a summary on the age recommendations for castration of the healthy bitch, castration before or after the first heat and the castration method most commonly used of Ovariohysterectomy and ovariectomy. The summary is based on a questionnaire answered by personnel from 20 veterinary clinics and animal hospitals evenly distributed throughout Sweden.The summary showed that Ovariohysterectomy was the most common method of castration and the recommendation in age ranged from 6-12 months. Regarding castration before or after the first heat 75% of the veterinary clinics and animal hospitals answered that they recommended castration after the first heat. Literature study shows that there are both advantages and disadvantages of castration of the healthy bitch and that it therefore is important that each bitch get a personal and individual evaluation before a decision is taken concerning a castration..

In Sweden, the most common way to castrate a bitch is by midline approach. In this study, flank and midline approaches are compared in order to evaluate incision by the flank as an alternative technique for Ovariohysterectomy in the bitch. The study was performed on straydogs in the central part of Thailand under field conditions. 32 bitches were included in the study. The castration technique was by flank and midline approach, alternating with every other bitch.

The aim of this study was to investigate the intraoperative surgical stress response in dogs undergoing Ovariohysterectomy and to compare acepromazine and medetomidine as premedications. 15 dogs diagnosed with pyometra were used in this study. Blood pressure and heart rate were used as parameters to measure surgical stress response. The surgery was divided into four phases. Phase 0 was the period 10 minutes before the skin incision, phase 1 was skin incision and opening of abdomen, phase 2 was manipulation of uterine horns, ligation and transection of mesovarium and phase 3 was ligation of cervix, removal of organs and closing the abdomen. The results showed that phase 2 was the most intense phase of surgical stress, regardless of which premedication the dogs received. When acepromazine and medetomidine were compared the results showed that within phase 3, all dogs that were given medetomidine had higher blood pressure compared to dogs that were given acepromazine. The dogs that were given acepromazine had higher heart rate than the dogs that were given medetomidine in phase 0, phase 2 and phase 3. .

This student report is about neutering male and female cats and compares early ageneutering to neutering at the traditional age of 6 months.The main focus in this report is early age neutering, which means that neutering isperformed when the kittens are between 6 and 16 weeks of age. This technique has beenused by shelters in the United States for a long time, to prevent the adopted cats fromreproduce and contribute to the problem of overpopulation.Two different surgical methods are also addressed; the ventral midline incision and thelateral flank approach. Ovariohysterectomy and ovariectomy are also compared.I also address which drugs are preferable when kittens are neutered and some importantguidelines where you have to be extra careful when dealing with kittens.These guidelines are the preanesthetic evaluation, calculating drug dosages and preventinghypothermia, hypoglycaemia and stress.The report also has a summary of the concerns regarding early age neutering such asanaesthetic risks, growth disorders and growth plate fractures, urologic diseases andimmune system dysfunction, obesity, altered metabolism and behavioural changes.The sex hormones and how they change after neutering is also included.At the end of the report there is a compilation of a questionnaire that consists of eightquestions that I sent out to various animal hospitals and veterinary clinics in Sweden..

Pyometra, chronic purulent metritis in metoestrus, is a common disease in intact bitches. About 25% of all bitches in Sweden have contracted the disease before ten years of age. Clinical signs of the disease are varied, and the course may be either slow or acute. The diagnosis is most commonly made by radiographical or ultrasonographical examination of the abdomen in combination with blood biochemical and hematological analyses. The safest and most efficient treatment of pyometra is surgical Ovariohysterectomy.There is room for improvement of both diagnostic tools and possible prognostic indicators for pyometra.Mast cells are large leucocytes, with granule that contain inflammatory mediators.

Rabbits carry a high risk of anesthesia related death. This study was part of a project to develop a form of total intravenous anesthesia (TIVA) with minimal effects on cardiac, respiratory and metabolic parameters. In the study, TIVA with sufentanil and midazolam (group TIVA, n=9) was compared with inhalation anesthesia with sevoflurane (group SEVO, n=9) in female rabbits undergoing surgery (ovariehysterectomi). All rabbits were pre-medicated with medetomidin and carprofen before anesthesia induction. Anesthesia was induced with TIVA (2.3 ?g/ ml sufentanil, 0.45 mg/ ml midazolam) at a rate of 4 ml/ kg/ h and the mean induction dose was 0.4 ?g/ kg of sufentanil and 0.1mg/ kg of midazolam.

The purpose of the present study was to explore if blood lactate levels are increased in bitches with pyometra, and if the lactate measurement could be used as a prognostic indicator and to determine outcome. The present study included 16 bitches with pyometra that were admitted to the University Animal Hospital, Swedish University of Agricultural Sciences, Uppsala, Sweden. For comparison, a control group consisting of 14 healthy staffowned bitches was also evaluated. In all bitches, a physical examination was performed and blood samples for analysis of haematological and biochemical parameters were obtained. In all bitches with pyometra, surgical Ovariohysterectomy was performed and a uterine sample for bacteriological culture and identification was collected.

Pyometra is a common and life threatening disease of intact bitches. The disease is caused by a hormonal influence on the uterus in combination with a bacterial infection. The most common treatment is Ovariohysterectomy, but several medical options are available to maintain fertility or avoid surgery and anaesthesia. Drugs that can be used for medical treatment are for example progesterone-receptor antagonists, prostaglandins and dopamine agonist. The present study focused on treatment with the progesterone-receptor antagonistaglepristone in combination with antimicrobial therapy.