The occurrence and degree of osteochondrosis was studied in 64 pigs raised in conventional systems (45) or organically according to KRAVs principles (19). In this blind study the growth plates of distal radius and ulna were examined macroscopically and radiologically searching for pathological lesions. One significant difference was shown in this study. Conventionally raised pigs diagnosed with osteochondrosis had more severe lesions in the distal growth plate of radius and ulna than the corresponding group of pigs raised organically. No significant difference was shown between the groups when all pigs were included. .

Several bulls in Sweden are culled because of lameness. Studies of beef bulls have shown that osteochondrosis is an important underlying cause of hind limb problems (Persson, 2003; Dutra, 1998). Osteochondrosis in horses, dogs, swine, poultry and man are well documentated in the literature, but there are few studies in cattle. The prevalence of osteochondrosis in dairy bulls in Sweden is unknown. The aim of this study was to investigate the presence and localisation of osteochondrosis in the hindlimbs of dairy bulls. This study consists of 48 one-year-old bulls divided into four groups related to which farm they came from.

Osteokondros är en vanlig multifaktoriell sjukdom hos stora och snabbt växande hundraser och kan drabba flera leder så som exempelvis armbågs- och bogleder. En lokal störning i den endokondrala benbildningen i epifysen eller metafysens tillväxtbrosk leder till ojämnheter i brosket, som i sin tur orsakar smärta och hälta. Osteokondros påverkar hundens välfärd såväl som människans användning av hunden. Kunskap om sjukdomsförloppet och faktorer som påverkar sjukdomsutveckling krävs för att förhindra uppkomst av osteokondros. Den här litteraturgenomgången syftar till att klargöra huruvida utfodring påverkar utvecklingen av osteokondros hos hund och i så fall på vilket sätt. Litteraturstudien har avgränsats till betydelsen av överutfodring med energi och protein samt över- eller underutfodring med kalcium och fosfor. För att en normal ledyta ska bildas krävs ett intrikat samspel mellan mekanismerna för skelettillväxt, endokondral benbildning samt benremodulering.

The main purpose of this study was to study the heredity of osteochondrosis (OC) in fetlock-, hock- or stifle joints within the Swedish half-bred population, using data from the regional animal hospital in Helsingborg. A large number of horses with clinical symptoms, for example lameness, are radiographed every year at the regional animal hospital in Helsingborg. In addition, many clinically healthy horses are radiographed in order to be sold (inspection radiographed / export radiographed). This study is based on electronically stored data from horses in both of these groups of patients that underwent joint radiography at the regional hospital in Helsingborg during the years 1992-1999. The first file (inspection file) contained 1035 observations from 983 horses that had their fetlock-, hock - or stifle joints radiographed for inspection or export. The other file (clinical file) contained 6121 observations from 3800 horses that were radiographed due to clinical symptoms in the fetlock-, stifle or hock joints.

Genetic parameters for four leg conformation traits in dogs (Canis lupus familiaris) are in this literature review summarized to investigate whether selective breeding could be useful to improve purebred dogs´ health and welfare. The four traits are leg length, leg weakness, hip joint and elbow joint conformation. When summarized, the genetic parameters are compared with genetic parameters affecting in pigs (Sus scrofa). Of the four traits, hip and elbow conformations were mostly studied in dogs. However, these traits were not widely studied in pigs.

On average half of the sows in Swedish piglet producing herds are culledannually. A significant portion of the sows are euthanized because of lameness orparalysis. Young sows and gilts are overrepresented in the category of animals,culled due to injuries in the musculoskeletal system. These injuries cause pain tothe animals. Early culling of sows/gilts also have economical consequences forthe producers.

This project investigated how elevation and vegetation type influences variation in plant litter phenolic content and protein precipitation capacity among and within common plant species for two different vegetation types, heath and meadow, in a subarctic ecosystem in the Abisko region of northern Sweden. As nutrient availability generally decreases with increasing elevation as a result of decreasing temperature, I hypothesised that phenolic content would increase with elevation and be higher on the heath than the meadow. To test this, the total phenolic content and protein precipitation capacity was estimated in leaf litter from 13 species in both heath and meadow vegetation across an elevational gradient ranging from 500 to 1000 meters above sea level (m.a.s.l.) in the study region. The results showed that elevation and vegetation type both had a strong impact on both variables. Total phenolic concentrations decreased with elevation for the meadow, and were greater for the heath than the meadow.

Osteochondros (OC) och osteochondrosis dissekans (OCD) är en störning i den indirekta, endochondrala bentillväxten hos unga snabbt växande hästar. När prestationskraven på hästen ökar vid en högre ålder kan det leda till att den utvecklar hälta. Flera studier har visat att ostechondros har en genetisk komponent. Syftet med föreliggande litteraturstudie är att ta reda på hur osteochondros nedärvs, hur olika selektionsstrategier påverkar prevalensen samt hur problemet kontrolleras inom aveln. Arvbarheten för OC och OCD i femorpatella leden var 0,07 respektive 0,02.

The aetiology of osteochondrosis (OC) is known to be complex and multifactorial. The occurrence of bone fragments in joints and their connection to osteochondral disease are no exception. In the hock and stifle joint of the horse this type of lesion has generally been considered to be of osteochondral origin, while the process behind these fragments in the fetlock joint has been up for discussion. The objective of this study was to determine the frequency and the localisation of OC in Swedish warmblooded horses. In order to do so all radiographs of stifle, hock and fetlock joints performed on Swedish warmblooded horses during the period of 1992-1999 at Regiondjursjukhuset in Helsingborg were examined and the material was divided into two groups.

Promoters are genetic elements that facilitate the transcription of a gene and they have been found in front of non-coding RNA (ncRNA) genes in different organ-isms, e.g. the model plant Arabidopsis thaliana. A similar element, DUSE, has been found in front of ncRNAs in the social amoeba Dictyostelium discoideum and a part of this project has been to analyze the function of this putative promoter element through cloning and expression studies. A construct to analyze the func-tion of DUSE was successfully designed and introduced into D. discoideum but full expression studies were not finished because of shortage of time.

The top selection of Swedish beef bulls are evaluated yearly by Svensk Köttrasprövning AB at Gismestad. The bulls are selected from six different breeds; Angus, Blonde d´Aquitaine, Charolais, Hereford, Limousin and Simmental, and are kept on straw bedding apart from a concrete alley in front of the feeding area during the six months of evaluation period. The bulls are evaluated according to their fertility scores, growth, exterior and temperament and the exterior, body posture and claw conformation reflect important qualities for their longevity. In spite of good values for fertility, it has been noticed in the last years that the fertility results and longevity have been unsatisfactory and claw and/or bone disorders have been suspected as a contributory cause. Persson et al. (2007) studied breeding bulls from Gismestad and other places, which had been slaughtered due to poor fertility (no pregnancies in the herd during their last year in service).

Trots mångåriga ansträngningar och även om relativt många hundar röntgas i Sverige idag, så orsakar armbågsleds- och höftledsdysplasi fortfarande stora problem inom många hundraser, t ex labrador retriever. Armbågsledsdysplasi (AD) och höftledsdysplasi (HD) klassificeras som utvecklingsrubbningar. Armbågsledsdysplasi (AD) är ett samlingsbegrepp för sådana förändringar i leden som redan hos den unga individen kan leda till osteoartros (OA). Armbågsledsartros innebär en onormal förslitning av ledbrosket i armbågsleden vilket ger upphov till benpålagringar. Olika typer av tillväxtrubbningar i och runt leden är orsak till förslitningen av ledbrosket och de senare uppkomna pålagringarna.