Sökresultat:
1 Uppsatser om Metyleringsstatus - Sida 1 av 1
Undersökning av global epigenetisk metyleringsstatus hos juvertumörer på hund :
Mammary tumors are the most frequent type of tumors in bitches in Sweden. Many
studies have been published concerning mammary tumors, but there is still much to
be learned about this disease.
One has, since some time ago, had the knowledge that addition to or removal of
methyl groups to genes can inhibit or activate gene-expression. Methylation and
demethylation is a normal phenomenon in the body and it is essential for the
development and survival of the individual. The risk of developing a tumor disease is
increased if the global methylationstatus is changed; if oncogenes demethylates
(activates) or if tumor suppressor genes methylates (inactivates). In the human
medicine one has seen that there are differences in methylationstatus between
different tumors.
In this study tumor and normal tissue from ten dogs were examined with regard to
methylationstatus.