The process of drug discovery is very slow and expensive. There is a need for reliable in silico methods; however the performance of these methods differs.This work presents a targeted study on how the drug discovery methods used in OpenEye?s tools ROCS, EON and FRED perform on targets with small ligands. It was examined if 12 compounds (markers) somewhat similar to AMP could be detected by ROCS in a random data set comprised of 1000 compounds. It was also examined if EON could find any electrostatic similarities between the queries and the markers.

Informationssäkerhet har idag en viktig roll inom organisationer. Det finns undersökningar som visar på att attacker ökar för varje år. För säkerhetskritiska organisationer som kommuner är det därför viktigt att man har uppdaterad säkerhetsteknik, då man lätt kan falla efter i det snabbt utvecklande ämnet informationsteknik. Uppgiften som gavs av Nexus AB var att kartlägga och utvärdera en kommuns informationssäkerhet. De ville få reda på hur det egentligen låg till med informationssäkerheten i en Stockholmskommun.

Keywords: ID-method, internet, security, digitzing, bank Background: The digitizing of our society continues to grow and more parts of our lives is spent on the internet. The banks are one of the institutions that is at the forefront of this development since they established themselves on a early basis. The banks meeting points have since this establishment moved from the regular bank office out on the internet. A problem that has occurred during this transfer is the possibility to positive ID a customer in a virtual world. It is essential to offer the customer methods to identify themselves that are both safe and easy to use.

The CASA-paradigm, Computers Are Social Actors, was introduced in the book "TheMedia Equation" by Reeves and Nass. One of their experiments concluded that we tend to be polite to computers in the same way as we are to people. In this study I have replicated Reeves and Nass experiment but instead of a text-based interface I have used a virtual agentin order to find out if we are polite to the agents, or still to the computer. Two experimental setups was conducted. The two setups had a common first part that was carried out on onecomputer with one agent.

More and more people today manage their social relationships through social networking sites. A social networking site is a virtual place where people can meet and interact with each other. On such sites, one can use the various features and attributes to present ourselves to the friends we have online. The central question of this report is what characteristics of relationships show on social networking sites. With the features and attributes that are represented and whether the architect for a social networking site affects the relationship between friends.

I en värld där kraven på flexibilitet, säkerhet och hårdvaruoptimering är nyckelfaktorer när det kommer till att välja IT-miljöer för företag blir virtuella skrivbord mer och mer poulära. Med dessa miljöer finns det också problem när det kommer till användarupplevelsen om nätverket ifråga inte kan uppfylla de krav som ett sådant system ställer. I detta arbete undersöks implikationerna vissa nätverksvariabler kan ha för en Virtual Desktop-infrastruktur, VDI. För att belysa dessa problem har två tester utförts på en VDI miljö. Det första testet gick ut på att mäta latensen då skrivbordsmiljön renderades för klienten från virtualiseringsservern vid olika nätverksdiamterar.

Incident response plans are faced with new challenges as organisations expands to the cloud, this thesis aims to highlight these challenges and their potential solutions. Our work has focused on managing the incident response in contrast to earlier work that has been focusing on preventing them.As with any development, security is seldom prioritized. Instead the focus are often aimed towards usability and functionality, which means incident response plans are written, implemented, forgotten and finally becomes obsolete. This could result in an organization losing their ability to produce acceptable forensic images, avoid severe downtime, or prevent similar incidents in the future, which are all important parts of incident response.Traditional incident response plans does not address incidents in the cloud. Thus, an absence of guidelines for managing incidents in the cloud becomes apparent.

The purpose of this study was to describe senior nurses? expectations concerning how a digital information and communication technology systems (ICT) can contribute to the improvement of care leadership and how it can strengthen ties between the school's theoretical world and the practical clinical work-based training (WP) in nursing. The study has a descriptive design with a qualitative approach. The study involved seven leading care nurses. Data were collected through semi-structured interviews.

This examination work is about implementation of Cisco Systems Network Admission Control (NAC) within a leading IT-company in region of Jönköping. NAC is a technique that is used for securing the internal network from the inside. NAC can verify that the client who connects to the network has the latest antivirus updates and latest operative system hotfixes. Clients who don?t meet the criteria can be placed in quarantine VLAN where they only have access to the update servers.

Dooria Sweden AB is one of the main door- and doorframe manufacturers inSweden. They deliver door frames for indoor use for project oriented buildingsites, for these types of building sites the doorpost comes pre-assembled. DooriaAB wants to minimize transport to reduce impact on environment and thetransportation costs of pre-assembled doorframes, this thru simplifying themethod of assembly.The main purpose of this thesis has been to develop a prototype solution thatbrings the three parts of the doorframe together with the same properties regardingstability and tightness of joints as the current method of assembly. A profile ofdemands and wishes were created in collaboration with Mårten Dragstedt, DeputyDirector of Dooria Sverige ABBy following the chosen method the authors have been able to produce a fullyfunctional prototype that meet the demands that were put on the product. Catia V5R20 has been used as an aid during prototype construction and virtual tests.

Användarupplevelser är en gren inom användbarhetsområdet som på senare år kommit att studeras alltmer. Orsaken till detta är att ny teknik medför andra krav på produkter än att produkter som sådana ska vara lätthanterliga. Produkten kan likväl ha som syfte att vara rolig att använda sig av.Studiens syfte var att studera användarupplevelser beträffande Surface-computing teknologi.Företaget Interactive Institutes innovativa Surface-computing produkt Virtual Autopsy Table fick exemplifiera Surface-computing teknologi i publika miljöer. Genom att använda denna uppmärksammade produkt som underlag är syftet att undersöka vilka designmoment som kan anses vara kritiska för upplevelsebaserad design. Studiens frågeställning blev:Vilka riktlinjer kan tas fram för att vägleda en designprocess att bli mer fokuserad påanvändarupplevelser vad gäller Surface-computing system?Med utgångspunkt från studiens datamaterial, så var en del av studiens syfte att ta fram riktlinjer.

This two years master?s thesis is about book circles for children, arranged by the public libraries in Sweden. The purpose is to gain knowledge about how children experience their participation in book circles, and how they experience their own reading. It focuses on children aged 10 to 12 years, and their leisure reading. The research questions are: What are the book circles? function for the participants? How and why do the children read? What kind of literature do they like? Do the children experience that their reading has developed through their participation in the book circles? What parts of the reading process do the book circles influence?The theoretical framework is threefold.

Since the beginning of the 1990s, Swedish society has gone through a great change. Firstly with the personal computer and then with the internet moving in to everyday life, a new arena for interaction with society evolved. Work, education, doing bank errands and reading or discussing the news, just to name a few, now all take place in the virtual world online. Not to mention social media sites such as twitter, instagram or facebook, the last of which has over half of the Swedish population represented as members.   Companies, corporations, interest groups, political parties and politicians must be aware of the massive impact that a post spread through social media can have.    This thesis will, with the text analyzing tool, argumentation analysis, and on the theoretical platform of political communications theory, analyze three of the most viral Swedish political posts spread over 120 000 times each, to see if there are any combined qualities that point to the fact that there is a formula for getting a post to become a viral success on social media.    The main result showed that of the three posts analyzed, all were built up around a factual thesis, argued for with foremost example arguments, not only appealing to the logical branch of argumentation but also to the ethical, and that they tended to be of high relevance and sustainability. The conclusion must therefore be that these are all qualities that tend to be of relevance for making a political post on social media into a viral success..

The aim of this paper is to investigate dominant beliefs and approaches to the "cultural entrepreneur" both within a public context, and also among business owners within the cultural field. What happens when ideas and attitudes in the public sector towards culture driven businesses meets the perspective of individual cultural entrepreneurs?This study is based on analysis of political documents about the cultural and creative industries (CCI) from the European union, national level and regional level. Interviews with six business owners in the field of culture and one representative of the Swedish region with the fictive name ?Alma? has been conducted.

The aim of this master's thesis is to study how the design of the music library space affects how it is used and its role as an arena for culture. This is done in form of a case study of Library 10 in Helsinki, a public library branch that specializes in music and information technology. The backdrop to the study is the changing context for cultural activity in the information society and the role of public libraries as public space and meeting place. By analyzing the distribution of space in the library, the distribution of functions and artefacts and the spatial use of the room, I interpret the ways in which this distributional logic produces a unique place for music and culture. I discuss the music library design in a space and place perspective, utilizing theoretical tools from cultural geography and the space theories of Henri Lefebvre.