Peste des Petits Ruminants (PPR) is a disease of major socioeconomic impact. It is an acute and highly contagious viral disease of small ruminants caused by the agent Peste des Petits Ruminants Virus (PPRV), a Morbillivirus closely related to Rinderpest virus (RPV) which was declared eradicated from the world in 2011. PPR has a high morbidity and mortality rate and is characterised by high fever, nasal and ocular discharge, pneumonia, necrosis and ulceration of the mucous membranes and inflammation of the gastrointestinal tract causing severe diarrhoea. The role of wildlife in the epidemiology of the disease is still unclear. The disease is currently affecting sheep and goat in 70 countries worldwide and this year (2014) FAO has announced a program to eradicate the virus by 2030. In Tanzania, the disease was first reported in 2008 and has since then spread to different parts of the country.

Patienter som läggs in på intensivvårdsavdelningar blir ofta sängliggande en längre period. Invasivt ventilatorbehandlade patienter blir inte alltid mobiliserade som de borde. Immobiliseringen hos patienterna har en rad negativa effekter på kroppen, men att låta mobiliseringen bli en prioriterad åtgärd kan vara utmanande för intensivvårdssjuksköterskan och teamet kring patienten. Syftet med denna studie är att beskriva effekter av tidig mobilisering för invasivt ventilatorbehandlade intensivvårdspatienter. Metoden som valts för att genomföra studien är litteraturstudie.

Luftvägssjukdomar är ett av de största hälsoproblemen bland dagens slaktgrisar. Problemet har ökat i takt med att besättningsstorlekarna och därmed smittrycket har ökat. Spolmask i närvaro av en ett annat smittämne som till exempel Mycoplasma hypneumoniae kan orsaka luftvägssjukdomar. Spolmask är en av de vanligast förekommande parasiterna hos gris och orsakar bland annat skador på grisens lungor. Det är ett problem bland såväl konventionella som ekologiska slaktgrisar.

Syfte: Syftet med studien var att undersöka svenska sjuksköterskors upplevelser av att arbeta inom den norska sjukvården.Metod: Kvalitativ design med deskriptiv ansats. Tio svenska sjuksköterskor med erfarenhet av att arbeta inom den norska sjukvården intervjuades. En intervjuguide med bakgrundsfrågor samt intervjufrågor med relevans för studiens syfte användes som underlag under intervjuerna. Intervjumaterialet bearbetades och analyserades utifrån Graneheim & Lundmans innehållsanalys (2003).Resultat: Upplevelsen av att arbeta som svensk sjuksköterska i Norge var individuell och erfarenheterna varierade beroende på anställningsform och sjuksköterskans personliga inställning till arbetet. En generell upplevelse bland de medverkande sjuksköterskorna var att arbetsbelastningen i Norge var relativt låg och att antalet patienter per sjuksköterska var lägre än vad de var vana vid.

Background Atelectasis is a commun respiratory complication related to general anesthesia and may contribute to pneumonia and acute respiratory failure. Atelectasis apear within 10 minutes after anesthetization and occur in 90% or more anesthezied patients regardless of age and gender. The aim of this study was to indentify if there are any evidence for which methods are ultimate or are most efficacious to reduce and prevent the formation of atelectasis.                                                                                                          Methods This study is a descriptive litterature study where 28 scientific studies have been indentified for review and analysis.                                                                                                               ResultsThe use of 100% oxygen during the induction of anesthesia favors the developement of atelectasis. This can be prevented by preoxygenation with oxygen content of 100% combined with a PEEP of 6-10 cmH2O. When free airway is secured, oxygenation with 100% was found to be unnecessary.

Noise in schools can have negative effect on the teaching environment and speech perception. The national Child Environmental Health Surveys (BMHE) conducted in 2003 and 2011 studied how 12-year olds experience their sound environment in school. Results showed that the number of pupils that experience annoyance from noise increased from 2003 to 2011.Aim: The aim of this study was to study how 12-year olds perceive their sound environment in school.Methodology and material: A quantitative questionnaire survey was conducted in the sixth grade at two schools. The questionnaire used included questions from BMHE and self-produced questions. Sixtynine students answered the questionnaire.Results: Over 50 % of the respondents experience annoyance from noise in school several times a week.

Långtidsbehandling med ventilator utan tillräcklig befuktning kan torka ut en patients luftvägarmed olika komplikationer som följd. Målet för detta examensarbete var att utveckla en ny teknikför att befukta och värma inandningsgasen. Ett fungerande koncept och en prototyp som styrkerkonceptet skulle tas fram.Marknaden för befuktare studerades och de vanligast använda befuktningsmetoderna granskadesför att hitta svagheter som behövde åtgärdas. De två vanligaste befuktartyperna är HeatedHumidifier och Heat and Moisture Exchanger. Den främsta nackdelen med Heated Humidifiervar dess tendens att övermätta luften med kondensutfällning som följd, och med Heat andMoisture Exhanger att inte tillräckliga fukt- och temperaturnivåer nåddes.Därför togs en ny design fram med målet att kunna styra fukt och temperatur oberoende avvarandra.

The aim: was to describe and compare a group of experts and critical care nurses' agreement in detecting delirium in intubated, ventilator treated patients with sedation / analgesia, before and after an in house training intervention with the instrument Confusion Assessment Method for the Intensive Care Unit (CAM-ICU).Method: A quasi-experimental study, one group pretest - posttest design. A convenience sample of 17 critical care nurses in a general intensive care unit included. To detect delirium the instrument CAM-ICU was used, 21 paired tests before and 22 after an educational intervention.Main Results: The results showed that after an in house training intervention sensitivity and kappa coefficient improved of the characteristic 1 "acute onset and fluctuating course," an improvement that was significant. In other features, and overall values were signs of numerical improvement and deterioration in sensitivity, specificity and kappa coefficient but no significant change.Conclusion: Implementing a new instrument for detecting delirium in clinical practice requires education and follow-up. A small sample of critical care nurses with varying ability to use the new instrument and the fact that patients' status may change rapidly making it difficult to draw any conclusions from this study.

In studies of serum, in the early 1930s, from patients with pneumonia, a factor was found. It could agglutinate certain pneumococcal species. This factor, which later became known as C-reactive protein (CRP), increased sharply during the early and middle stages of the disease. CRP was identified as an acute phase protein and found especially in bacterial infections. CRP is synthesized in the liver by stimulation of interleukin 6 (IL-6), which is produced by the monocytes, and consists of five non-covalently bound subunits.The aim of this study was to compare two different analytical instruments (Vitros 5.1 FS Ortho-Clinical Diagnostics and QuikRead CRP Orion Diagnostica) for CRP analysis.

The Bovine respiratory syncytial virus (BRSV) causes bronchiolitis and interstitial pneumonia, predominantly in calves, and is a major cause of bovine respiratory disease worldwide. In humans, BRSV is paralleled by the closely related Human respiratory syncytial virus (HRSV), an important cause of respiratory disease, most severe in infants.The clinical signs and pathology during RSV infection is caused, not only by the direct effects of viral replication, but also by the response of the host immune system. The immunopathology of RSV has long obfuscated our understanding of the disease, and development of effective treatment and vaccines will be very difficult until greater knowledge is gained.One of the components of the immune system that has come into focus in RSV research the last few years, is the Toll-like receptor 4 (TLR4). The TLR4 receptor is well known as the receptor that binds lipopolysaccaride (LPS), and initiates the host response to bacterial infection. Recently, it has been shown that the fusion protein of RSV also interacts with, and up-regulates the expression of, the TLR4 receptor.

The Bovine respiratory syncytial virus (BRSV) causes bronchiolitis and interstitial pneumonia, predominantly in calves, and is a major cause of bovine respiratory disease worldwide. In humans, BRSV is paralleled by the closely related Human respiratory syncytial virus (HRSV), an important cause of respiratory disease, most severe in infants.The clinical signs and pathology during RSV infection is caused, not only by the direct effects of viral replication, but also by the response of the host immune system. The immunopathology of RSV has long obfuscated our understanding of the disease, and development of effective treatment and vaccines will be very difficult until greater knowledge is gained.One of the components of the immune system that has come into focus in RSV research the last few years, is the Toll-like receptor 4 (TLR4). The TLR4 receptor is well known as the receptor that binds lipopolysaccaride (LPS), and initiates the host response to bacterial infection. Recently, it has been shown that the fusion protein of RSV also interacts with, and up-regulates the expression of, the TLR4 receptor.

Staphylococcus aureus is the most clinically important Staphylococcus species and is associated with high mortality in patients with positive blood cultures. S. aureus bacteria may cause a variety of disease manifestations ranging from minor skin infections to life-threatening conditions such as pneumonia, meningitis, osteomyelitis, endocarditis, toxic shock syndrome (TSS) and sepsis. This microorganism belonging to the gram positive cocci may also be part of the normal flora. In Sweden, penicillinase-stable penicillins are the primary alternatives to treat S.

The aim: was to describe and compare a group of experts and critical care nurses' agreement in detecting delirium in intubated, ventilator treated patients with sedation / analgesia, before and after an in house training intervention with the instrument Confusion Assessment Method for the Intensive Care Unit (CAM-ICU).Method: A quasi-experimental study, one group pretest - posttest design. A convenience sample of 17 critical care nurses in a general intensive care unit included. To detect delirium the instrument CAM-ICU was used, 21 paired tests before and 22 after an educational intervention.Main Results: The results showed that after an in house training intervention sensitivity and kappa coefficient improved of the characteristic 1 "acute onset and fluctuating course," an improvement that was significant. In other features, and overall values were signs of numerical improvement and deterioration in sensitivity, specificity and kappa coefficient but no significant change.Conclusion: Implementing a new instrument for detecting delirium in clinical practice requires education and follow-up. A small sample of critical care nurses with varying ability to use the new instrument and the fact that patients' status may change rapidly making it difficult to draw any conclusions from this study.

Staphylococcus aureus is the most clinically important Staphylococcus species and is associated with high mortality in patients with positive blood cultures. S. aureus bacteria may cause a variety of disease manifestations ranging from minor skin infections to life-threatening conditions such as pneumonia, meningitis, osteomyelitis, endocarditis, toxic shock syndrome (TSS) and sepsis. This microorganism belonging to the gram positive cocci may also be part of the normal flora. In Sweden, penicillinase-stable penicillins are the primary alternatives to treat S.

Staphylococcus aureus is the most clinically important Staphylococcus species and is associated with high mortality in patients with positive blood cultures. S. aureus bacteria may cause a variety of disease manifestations ranging from minor skin infections to life-threatening conditions such as pneumonia, meningitis, osteomyelitis, endocarditis, toxic shock syndrome (TSS) and sepsis. This microorganism belonging to the gram positive cocci may also be part of the normal flora. In Sweden, penicillinase-stable penicillins are the primary alternatives to treat S.