The Bovine respiratory syncytial virus (BRSV) causes bronchiolitis and interstitial pneumonia, predominantly in calves, and is a major cause of bovine respiratory disease worldwide. In humans, BRSV is paralleled by the closely related Human respiratory syncytial virus (HRSV), an important cause of respiratory disease, most severe in infants.The clinical signs and pathology during RSV infection is caused, not only by the direct effects of viral replication, but also by the response of the host immune system. The immunopathology of RSV has long obfuscated our understanding of the disease, and development of effective treatment and vaccines will be very difficult until greater knowledge is gained.One of the components of the immune system that has come into focus in RSV research the last few years, is the Toll-like receptor 4 (TLR4). The TLR4 receptor is well known as the receptor that binds lipopolysaccaride (LPS), and initiates the host response to bacterial infection. Recently, it has been shown that the fusion protein of RSV also interacts with, and up-regulates the expression of, the TLR4 receptor.

Personer som drabbas av kronisk njursjukdom och startar behandling med hemodialys får en förändrad livssituation. Kärlaccess är en förutsättning för behandling och är personens framtida livlina. Sjuksköterskans uppgift är att ge stöd och stärka personens förmåga att uppleva hälsa trots sjukdom. Möjlighet att nå delaktighet och ökad egenvård är olika för varje enskild person och sjuksköterskan behöver bred kunskap för att möta detta behov. Syftet med studien, som utfördes som en litteraturöversikt, var att utifrån patientperspektivet belysa erfarenheter av hur kärlaccess kan påverka hälsan hos personer i hemodialys.

ABSTRACT Epilepsy describes a neurologically caused condition which involves seizures. Epilepsy can be classified according to different types of causes and the nature of seizures can vary. Medication for epilepsy in dogs is limited in comparison with human medicine. Idiopathic epilepsy is the most common neurological disease and one of the most common genetic diseases in dogs. Because epilepsy has a higher prevalence in certain breeds, there is reason to suspect that it is a hereditary disease. The inheritance of idiopathic epilepsy is for most breeds not determined, except for a few variants of the disease.

Chronic valvular disease (CVD) is the most common cardiac disease in dogs, which account for 75% of all the cardiac cases. Cavalier King Charles spaniel (CKCS) is the most affected breed and it´s 13th times more likely that a CKCS, between the age of 7-10 years, will die or be euthanized for cardiac disease, compared with other breeds. The prevalence has been proven to bee independent of coat color and weight but highly dependent on age and gender in CKCS. In 2001 the Swedish Kennelclub and the Special club for cavalier King Charles spaniel created a breeding program against CVD in CKCS. In this program dogs are not allowed to breed until 4 years of age and have to have a heart auscultation without murmurs.

Haptoglobin is an acute phase protein with important biological role because of its capacity to bind to haemoglobin. Haptoglobin exists in three major genetic polymorphism types: Hp1-1, Hp2-1 and Hp2-2, the distribution of which has been associated with abdominal aortic aneurysm (AAA), an asymptomatic aortic disease common among men older than 65 years.    Five different electrophoretic methods were tested according to their ability to separate the haptoglobin phenotypes. The detection was based on a produced hemolysate of blood in which haemoglobin binds to haptoglobin thereby forming a complex that can be detected by specific haemoglobin staining using TMB-dihydrochloride and hydro peroxide as substrate resulting in an azure-green color of the bands. Samples from 15 patients who had suffered surgery for not broken AAA, that is more than5.0 cmaortic diameter, and 15 samples from matched controls were analyzed.    Among the five tested electrophoretic methods best migration and separation was seen on the pre-cast agarosgel Hydragel HR on the instrument Hydrasys. The other four methods gave less successful results.

Perifer vaskulär insufficiens innebär arteriell och/eller venös cirkulationssvikt i nedre extremiteter, vilket kan förorsaka bensår. Vaskulär insufficiens i benen är ett ökande hälsoproblem som ofta är ett mycket smärtsamt tillstånd och kan ha stora konsekvenser för den drabbade i dennes dagliga liv. Litteraturöversikt valdes som metod för att besvara syftet; att beskriva forskning om patienters upplevelser av hur perifer vaskulär insufficiens i de nedre extremiteterna påverkar det dagliga livet. Detta utifrån Carnevalis omvårdnadsteori om dagligt liv funktionellt hälsotillstånd. Stora inskränkningar i dagligt liv på grund av sjukdomen identifierades i litteraturen.

The prime aim of this thesis was to investigate whether high or low iodine intake during certain periods of life was, or was not a strong risk factor for the development of canine lymphocytic thyroiditis (CLT). And secondly, if a high or low selenium intake in a combination with high or low iodine intake also may have an influence on that risk factor. To investigate this, a dietary questionnaire was sent out to dog owners. The dogs were selected from an ongoing genetic study of CLT. The questions investigated brand and type of feed during different life stages (puppy, junior and adult) and also if there were any use of dietary supplements.

Background: Breast cancer is one of the most common types of cancer in the world and it usually affects elderly women. However, there are between 600-700 cases per year in Sweden where women under the age of 45 are diagnosed. Removal of the breast or part of the breast, hair loss, fatigue and nausea as a result of the breast cancer treatment has an emotional and physical impact on the women?s lifeworld. The nurse should build a relationship with the women to identify and meet their needs. Aim: To describe younger women?s experiences of getting a breast cancer diagnosis and life afterwards.Method: Four biographical books were analyzed to match the aim of the study.Result: The findings were that the women experience similar thoughts and feelings when it comes to living with a cancer diagnosis.

The aim of this study was to describe the importance of diet and physical activity related to Diabetes Mellitus (diabetes). Method used was a descriptive literature study based on empirical studies. The study shows that diet, physical activity and lifestyle-changes are very important factors when it comes to preventing and treating of diabetes. By the right diet and physical activity the treatment with medications in some cases can be superfluous and people with the disease could live longer and be healthier during their lifetime. Nurses have the responsibility to educate, inform and make sure that the diabetic patient gets the best care as possible specially suited for this individual patient.

Sahlgrenska Academyat University of GothenburgDepartment of internal medicine and clinical nutritionAbstractTitle: Can exclusive enteral nutrition replace steroid treatment in pediatric Morbus Crohn?Author: Hanna Rymark Lehnér and Josephine PetterssonSupervisor: Mette AxelsenExaminer: Anna WinkvistProgramme: Dietician study programme, 180/240 ECTSType of paper: Examination paper, 15 hpDate: May 23, 2012Background: Morbus Crohn is a chronic inflammatory bowel disease which periodically causes great suffering for the patient. There is solid scientific evidence that treatment with steroids effectively induces and preserves remission. However, side effects are many and a great risk for stunted growth and skeletal development exists in children. A widespread view is that exclusive enteral nutrition is as effective as steroids in pediatric Crohn´s.

Hjärt-kärlsjukdom är idag en av de största folksjukdomarna i Sverige med högst mortalitet till följd. Flera studier visar att uppföljning av patienter, informationsbehov och stöd till patienter efter utskrivning från sjukhusen till primärvården är otillfredsställande. Det finns endast ett fåtal studier som visar på patienternas egna upplevelser av att leva med hjärtinfarkt. För att kunna förbättra vården till dessa patienter är det viktigt att ta del av patienternas egna upplevelser av att leva med en hjärtsjukdom. Syftet med studien är att beskriva patienters upplevelser av att leva med hjärtsjukdom ur ett patient- och livsvärldsperspektiv. Metoden i studien är kvalitativ intervju.

Hypertrophic cardiomyopathy (HCM) is the most commonly diagnosed cardiac disease in cats. The phenotype varies from mild focal thickening to severe concentric hypertrophy at the left ventricle. Two separate myosin binding protein C (MYBPC3) mutations have been identified in Maine coon cats (A31P and A74T) and one in Ragdoll cats. All three of them seem to cause familial HCM in an autosomal dominant pattern. The purpose of this study was to investigate the presence of these three mutations in population cats of different breeds with HCM in Sweden. The results may show if HCM is present in the absence of these mutations.

Background: Contracting asexually transmitted disease is strongly associated with stigmaand shame. Stigma associated with these diseases has a significant impact on self-image andpropensityto seek care. Despitehigh incidencethere is a generallack of awareness about therisks and theeffectsthatthese diseases have on both mental and physical health. Health carepersonnel are experiencing difficulties to meet and care for these patients. Aim: The aim ofthis studyisto describe patients'experiences of health care after they were diagnosed with asexually transmitted disease.

Secondary deciduous forests, which have their origin in earlier pasture- and meadow-land in slopes along the lower reaches of the Ume river, are thought to contain high nature conservation values, in spite of a relatively low age. The aim of this study was to clarify how factors as historical use, exposition, disturbance dynamics and successional age influences the conservation values in these types of riparian forests and how this can be implicated in the practical work with conservation and management at Umeå municipality. Sample plots were placed in seven stands with a variation of their historical use, exposition, disturbance dynamics and age of succession. Conservation values as structure, tree-regeneration, abundance and composition of vascular plants, amount of dead wood and the abundance of signal-species were measured and registered. The species composition and especially the composition of tree species, differed between forests with different exposition and different historical use.

Different forms of relaxing methods can be used in rehabilitation for individuals with tinnitus and Ménièré?s disease. Research continues to find convincing proof of effects from the different methods. This study presents methods of relaxing, massage and Mindfulness, as possible complementary rehabilitation tools.The purpose of this study was to investigate opinions about relaxing from professionals working with hearing care. A qualitative approach with phenomenological influence was chosen for the study.