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359 Uppsatser om Tumor initiating cell - Sida 8 av 24
Early immune responses to an adjuvant (AbISCO-100) tested in porcine peripheral blood mononuclear cell
Immune stimulating complex (iscom) matrix is a formulation that is used as anadjuvant within research. The capability of the iscom matrix to elicit an immuneresponse when not present together with an antigen has not been extensivelyinvestigated. One way to evaluate the status of the immune system is to measure theamount of cytokines that usually are produced by various cell types during an immuneresponse. The aim of the present study was to evaluate the early immune responses inporcine peripheral blood mononuclear cells (PBMC) after stimulation in vitro with theiscom matrix, AbISCO®-100. The immune response was evaluated by measuring themRNA expression for various cytokines, a chemokine receptor (CXCR4) andregulator of G-protein signaling (RGS16) in porcine PBMC after stimulation withAbISCO®-100 or other inducers like a lipopolysaccharide (LPS) and a CpGoligodeoxynucleotide (ODN 2216) used as controls.
Improvement of positive strand assay used in detecting positive and negative RNA of hepatitis E virus
Background: Hepatitis E (HEV) is a small, non-enveloped virus that belongs to the viral genus Hepevirus. HEV is a positive sense single-stranded RNA virus and there is insufficient information regarding its replication. This is mainly because the virus has low capacity to grow in normally used cell cultures. Many specific strand assay detection studies have been done in order to understand more about HEV replication. Unfortunately, these assays have the disadvantage of giving false positive results.Aim: The aim of this project was to improve the positive strand assay to increase specificity and eliminate false positivity which is due to high sensitivity of the polymerase chain reaction (PCR).
Gradering av kutana mastcelltumörer hos hund
Nedbrytningshastigheten för organiskt material i marken kan komma att förändras vid varmare klimat. I dagsläget råder dock oenighet om hur nedbrytningen av organiskt material kommer att reagera på förändrade temperaturer; forskningsrapporter pekar åt olika håll. För att kunna förutsäga framtida scenarier är det viktigt att vi får kunskap om hur organiskt material kan komma att påverkas. Om koncentrationen av koldioxid i atmosfären ökar och den globala medeltemperaturen stiger kan nedbrytningshastigheten för organiskt material öka. Detta kan leda till en positiv feedback loop där mer koldioxid avgår från marken till atmosfären.
Identifiering av gallringsbehov med hjälp av flygburen laserskanning :
Thinning is one of the most important silvicultural activities in middle aged forests, partly to minimize damages and partly because it leads to earlier harvesting revenues and increases the value of the remaining trees. There are many different indices used to describe stand density and thereby the need of thinning in forests today. Studies have shown that forest variables can be estimated with high accuracy using airborne laser scanning and it is likely that the method could also be used to estimate forest density indices. In this study, the possibility of using the forest density index ?H² to determine and map priorities for thinning operations for a forest area was examined.
Överviktens gåta : en intervjustudie om framgångsfaktorer för initiering och vidmakthållande av en livsstilsförändring
Övervikt och fetma anses vara ett globalt folkhälsoproblem, vars omfattning tycks ha ökat de senaste årtiondena. Förklaringen till det anses ofta vara en västerländsk livsstil bestående av kaloririk kost och bristande fysisk aktivitet. Att lyckas med en livsstilsförändring tycks därmed viktigt, men svårt. Syftet med studien var att identifiera framgångsfaktorer som bidragit till initierande och vidmakthållande av en livsstilsförändring. Enskilda intervjuer, med tre kvinnor och tre män, genomfördes därför med individer som vidmakthållit en livsstilsförändring i minst två år.
Mastcellens roll vid atopisk dermatit hos hund
SAMMANFATTNINGDenna litteraturstudie har gjorts med syfte att utöka kunskapen om atopisk dermatit hos hund med fokus på mastcellens roll i immunopatogenesen. Atopisk dermatit är en relativt vanlig sjukdom som kan drabba alla hundar oavsett ras; den är oftast livslång och kräver visst arbete för att diagnosticera och behandla med gott resultat. Förutom att det är ett problem hos hundar, finns även ett nära samband med atopiska sjukdomar hos människa, och hundar fungerar som en bra modell för forskning på humansidan.Trots omfattande forskning, vet man fortfarande inte varför sjukdomen uppkommer. Många teorier finns kring den immunologiska bakgrunden, men stora delar är fortfarande okända. Att mastcellen spelar en nyckelroll är dock allmänt vedertaget.
Solenergi : en lönsam investering för ett lantbruk?
A possible way to reduce pollution and slow down the process of global warming is to increase the usage of renewable energy sources. One of these renewable energy sources is solar power. With the aid of solar panels and solar cells the energy from the sun can be transformed into both heating and electricity. The requirement to use the sun in this fashion is a suitable surface, for example a big roof, an angle between 40-60 degrees and that the surface should be exposed to the south. Almost every farm meets these requirements.
Projektering av robotcell
Syftet med examensarbetet var att projektera en fysisk robotcell till Haldex i Landskrona, tillverkare av bromshävarmar, då det finns ett behov hos dem att effektivisera sin produktion för att kunna bibehålla konkurrenskraften och tillverkningen i Sverige. Bromshävarmen är en mogen produkt vilket medför att det inte skulle bli lönsamt att omforma den utan istället fokusera på tillverkningen. Därför vore lösningen att automatisera den del av monteringslinan som inte tillför något värde till slutprodukten. Robotcellen kommer att placeras på bromshävarmarnas monteringslina som en automatiserad station vilken ska utföra kvalitetskontroll av bromshävarmarna. Examensarbetet ingår i ett pågående forskningsprojekt på Mälardalens högskola inom Lean Automation, med Robotdalen och Haldex.
Hur en övergång till ett automatiskt mjölkningssystem påverkar juverhälsan :
Automatic milking systems (AMS) have been in commercial use since 1992 and have since 1998 increased a lot. The objective of this study has been to examine the development of udder health on farms converting to AMS. The study also included a comparison of how udder health developed depending on how farms handled cows with mastitis. This was because farms choose to either milk cows with mastitis in a separate barn or in the milking robot.
Other studies on udder health on commercial farms have shown that somatic cell count increases both among individual cows and in the bulk milk when converting to an AMS. No differences between before and after converting to AMS in the proportion of cows treated for mastitis can be found in the literature.
Use of oxytocin to improve diagnosis of subclinical mastitis caused by Staphylococcus aureus
Mastitis, inflammation in the udder tissue, caused by S. aureus is a big problem in dairy cattle production. It causes suffering for the cow and curing or replacing the infected cow is costly for the farmer. It is known that beef cattle also suffer from mastitis caused by S. aureus.
Prevalence of subclinical mastitis and udder pathogens in small holder dairy farms in Mapepe, Batoka and Choma areas in Zambia
Subclinical mastitis (SCM) is a well-known problem in the dairy sector, where it causes severe economic losses mainly due to reduced milk production. This is a problem not only in the western world but also in developing countries. Surveys from different developing countries have shown a SCM prevalence of 52.4 ? 88.6 % at cow level and 26.7 ? 63.2 % at quarter-level. To combat mastitis is important to optimize the milk production of the cow.
Derivativ talan och Corporate Governance. En komparativ studie ur ett rättsekonomiskt perspektiv
The world is getting smaller. Global markets, political processes and communication technology bring people together. Even though many of these processes are dynamic and constructive, they have also resulted in a need for better and more effective ways of international conflict resolution. This thesis investigates central issues connected to the concept of humanitarian interventions in relation to current and future legislation of the European Union. The overall question is whether the rapid globalization process has resulted in a change of international law towards more liberal view where authorization of the security council is not always needed? And, if there has actually been such a liberalization, how does that affect the legal possibilities for the European Union to carry out armed operations without the consent of the global community?The conclusion of the thesis is that international law has been modified mainly in two aspects: First, the concept of sovereignty is no longer seen merely as a right of the nation, but also as a responsibility.
Vision Malmö - En analys av Malmö stads visioner kring stadens utveckling
This thesis is a critical discourse analysis of the vision of Malmös contemporary urban development. By analysing official documents produced by Malmö municipality our aim is to make discursive and sociolcultural practices in the constitution and construction of the city visible and problematicize them. To do so we use critical discourse analysis and theories on Urban Studies. Malmö is a city historically labeld as a ?labour- city?, with heavy industry as its main labourmarket.
Föräldrars uppfattningar om förändringar gällande aptit och måltidssituationer hos barn som medicineras mot ADHD vid Habiliteringen vid Uppsala läns landsting
The aim of this study was to examine if parents, of children diagnosed with ADHD, exprerienced any changes regarding their childrens appetite after starting psycostimulant treatment. Further more the aim was to examine what kind of changes concerning the appetite that were found and if they affected the meal situation as a whole.Method: A questionnaire study was conducted in the spring of 2011. The study included 81 parent?s to children who were enrolled at the Habilitation in Uppsala and medicated with psychostimulants for ADHD. The children's ages ranged between six and 18 years.
Humanitära interventioner. Europeiskt handlingsutrymme i förhållande till ett modernt interventionsbegrepp
The world is getting smaller. Global markets, political processes and communication technology bring people together. Even though many of these processes are dynamic and constructive, they have also resulted in a need for better and more effective ways of international conflict resolution.
This thesis investigates central issues connected to the concept of humanitarian interventions in relation to current and future legislation of the European Union. The overall question is whether the rapid globalization process has resulted in a change of international law towards more liberal view where authorization of the security council is not always needed? And, if there has actually been such a liberalization, how does that affect the legal possibilities for the European Union to carry out armed operations without the consent of the global community?
The conclusion of the thesis is that international law has been modified mainly in two aspects: First, the concept of sovereignty is no longer seen merely as a right of the nation, but also as a responsibility.