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359 Uppsatser om Tumor initiating cell - Sida 6 av 24

Återvinning av skönlitteratur - Återvinningsverktygens anpassning efter användares sökbeteenden : En fallstudie på Trelleborgs bibliotek

Traditionally the content of fiction has not been described, analyzed, classified and/or indexed to the same extent as non-fiction. As a consequence, this lack of content analysis has resulted in unsatisfactory fiction retrieval in relation to users seeking and search behaviour. This fact is why this Master s thesis is written. The total of library users' seeking and search behaviour is investigated in order to suggest methods to improve user adapted fiction retrieval tools. Suggesting relevant fiction retrieval tools corresponding to users' seeking/search behaviour is another aim of the study.

The role of mast cells and mast cell mediators in the development of atopic dermatitis in a mouse model

Atopic dermatitis (AD) is a complex, often lifelong allergic disease affecting around 10 % of both dogs and humans. The hallmark symptom is severe pruritus, causing a lowered quality of life. Mast cells (MCs) are known to play an important part of the immunopathogenesis, promoting a faulty T helper cell type 2 (Th-2) response which follows by a production of specific immunoglobulin E (IgE) antibodies towards environmental allergens (Ag). To further investigate the role of MCs and its mediators in the progression of AD, a low-calcemic vitamin D3 analog (MC903) was used to induce AD-like symptoms locally on the ears of two different knock-out (KO) mouse strains. The first strain was Wsh-/- mice deficient in MCs.

Demonstratortest av gassensor baserad på tryckt organisk elektronik och jonledande papper

Researchers at Karlstad University have developed a method for making paper ion conducting. The reasearchers want to test this technique in various applications and produce products that make use of the ion-conducting paper. Hopefully this will drive the development forward and result in new applications for the ion-conducting paper.This study was to test the possibility of manufacturing a gas sensor of conducting paper along with electrodes of conductive polymers printed on the paper. By comparing the paper sensor with an electrochemical cell in which the electrodes of conductive polymer replaces electrodes of metal and ion-conductive paper replaces the liquid electrolyte in the electrochemical cell, it was hoped that it would be possible to measure the oxidation and reduction reactions that a gas could introduce at the electrodes.It was shown that it is possible to measure a potential difference in the range of 0.3 V to 0.5 V between the electrodes when exposing an electrode to 100% oxygen. The reaction that takes place is relatively slow and the reaction rate is partly due to the distance between the electrodes.Since the sensor can measure oxidation and reduction reactions it is possible that, in further development of a sensor, the sensor can be made ??into a versatile sensor with more applications than gas measurement as there are many more ways to oxidize or reduce the electrodes than by exposure to oxygen.During the study there have been discussions and meetings held with various companies in the sensor industry to be able to specify what the market demands of a sensor made ??of paper and the requirements that must be placed on the sensor for it to be interesting for the companies..

Cytologiska bedömningens påverkan på analysen av bronkoalveolärt lavage (BAL) samt förhållandet mellan andelen mastceller och proinflammatoriska cytokinmediatorer i BAL hos häst :

Inflammatory airway disease (IAD) is a respiratory disorder that most commonly affects young horses performing at a high level. The clinical signs are often mild but the disorder can cause a marked decrease in performance to a point where the horse has to be taken of training and competing. The aetiology underlying IAD is not yet fully understood. One current theory is that a type I-hypersensitivity reaction due to allergens in the environment is the cause in some horses. The most reliable diagnostic method is a bronchoalveolar lavage (BAL) since it reflects the inflammatory status in the most distal parts of the lungs, which are affected in IAD.

Cellulär automat simulerar utbredning av Taraxacum

I detta arbete undersöks vilken grad av inomartskonkurrens som ger upphov till ett observerat utbredningsmönster av maskrosor (Taraxacum sect. Ruderalia). Maskrosor har både fröspridning och vegetativ förökning. Studien hypotiserar att utbredningen kan beskrivas utifrån enkla regler för spridning och konkurrens. Dessa används i simuleringar med en binär cellulär automat där utveckling sker i deterministiska tidssteg.

Det självförsörjande passivhuset

The housing sector uses 40 % of the energy in Sweden and half of the electricity usage. Theuse of energy is the main reason to the increasing rate of carbon dioxide in the atmosphere.This is the main motive but also a wish of higher safety, that is a higher rate of selfsufficientenergy production in Sweden, we want to decrease the need of using fossil fuel. Now whenthe energy price rise, the interest in energy issues increase and more people discuss thepossibility of reducing the usage of fossil fuel. A change to renewable energy such as sun,wind and water is the only solution where we can get a sustainable development.One way to contribute to a better use of energy is to build in the principle of passive house.The house is being built with a thick and tight insulation. If you use a heat-exchanger withhigh degree of efficiency and a final heating battery on the ventilation system, the heat fromlamps, devices and the ones living in the house should be enough to fulfil the criteria ofliving.

Hundens parvovirus : patologi och riskfaktorer

Canine parvovirus is associated with two disorders: enteritis, which is common, and myocarditis, which is rare. Prominent clinical signs of parvovirus enteritis are vomiting, diarrhea and rapid dehydration. Canine parvovirus type 2 (CPV-2) is very contagious. When CPV-2 first emerged it had high rates of mortality, but later studies have shown that most infections are self-limiting and do not require veterinary care. Mortality rates vary greatly, and therefore it is important to determine risk factors for developing severe canine parvovirus enteritis.

Jämförelse av solhybrider

Research in solar energy is taking big steps in both solar heating and solar electricity. It´s not only the technologies alone, but also the combination of both solar electricity and solar heating which is what is called a solar hybrid. The idea of a solar hybrid is that a solar cells efficiency decrease with increased temperature and can with help from a solar collector be cooled and the heat can be utilized. This thesis report compares heat production and electricity production with respect of, in first hand, a solar hybrids geometry in the cooler. The theory chapter describes solar heating and how different solar cell technologies work and their environmental impact at the production and how compatible these technologies are for the solar hybrid.

Förutsättningar för kunskapsspridning - En fallstudier av affärsområdet Media & Kommunikation inom Cell Network

Sammanfattning Titel Förutsättningar för Kunsskapsspridning- en fallstudie av affärsenheten Media & Kommunikation inom Cell Network Författare Jacob Almstedt, Magnus Nilsson & Anja Trönnberg Handledare Lars Bengtsson & Jan-Inge Lind Seminarium Kandidatseminarium i Tillväxtföretag ? ?hur gick det & hur kan det gå?? Syfte Syftet med denna uppsats är: 1. Att identifiera för fallföretagen relevanta förutsättningar för intern kunskapsspridning och utifrån dessa utveckla en situationsanpassad analysmodell. 2. Att analysera fallföretagen utifrån analysmodellen.

Framtagning av normalt referensintervall för RDW och retikulocyter på hematologiinstrumentet ADVIA 2120

Erythropoiesis is a complex and carefully controlled process which is mainly regulated by erythropoietin. Using flow cytometry cells in a blood sample can be analyzed one by one. ADVIA 2120 using flow cytometry for analysis of red blood cells (RBC) and reticulocytes. Red blood cell distribution width (RDW) is a component of the RBC method. RDW indicates size variation on erythrocytes and is measured as a percentage of the mean cell volume (MCV). By measuring the RDW anemia can be divided into makrocytic, microcytic or normocytic. Reticulocytes refract light more strongly than red blood cells because they contain some cellular debris. The number of reticulocytes in the peripheral blood reflects erythropoiesis in the bone marrow. The purpose of this project was that by approved methods to establish reference ranges for the parameters, RDW and reticulocyte counts.The individuals who participated in the study, n=124, were considered healthy and had varying ethnicity. Reference subjects had not donated blood the last six months and participation in the study was voluntary.The statistic evaluation includes examination of distribution, and reference ranges for both men and women were established using the 2.5:t and 97.5:t percentiles. The calculated reference interval for RDW was between 12.0 ? 14.3% and the calculated reference interval for reticulocytes was between 38.0 ? 112.8 x109 cells/L. The results showed a significant difference between males and females for the parameter reticulocytes was seen. The difference indicates that different reference ranges should be established for men and women (p<0,0001). No significant difference between males and females were seen for RDW (p=0,74) indicating that the same reference ranges can be used for both men and women. .

An image-based method for identification of new inhibitors of Signal Transducer Activator of Transcription 1

Background: Chemotherapy and radiation resistance are major causes of failure in cancer treatment. The response to treatment in cancer cells depends on several mechanisms and pathways such as Janus kinases-signal transducers and activators of transcription JAK/STAT pathway. STAT1 was the first described transcription factor in the STAT family. STAT1 is activated by stimulation of signaling proteins such as type II interferon (IFN- ?) and the activated STAT1 translocates from cytoplasm to nucleus.

Skattning av biverkningar : Sjuksköterske- och patientuppfattning om behandlingsrelaterade biverkningar vid stamcellstransplantation.

A possible treatment for patients with lymphoma and myeloma is stem cell transplantation (SCT). SCT is preceded with cytostatic treatment. There are several side effects related to this treatment, for example fatigue, nausea, constipation/diarrhoea, pain, mucositis and loss of appetite. Aim: Investigate which side effects related to the treatment where most troubling after SCT and if nurse assessment and patient assessment differ. Methods: A quantitative empirical study with repeated measuring.

Avkodning av streckkoder i mobila enheter

The most common method for identifying merchandise in the commerce is by barcodes. Symbian OS is an advanced operating system aimed at cell phones and the most commonly used in smart phones. Opportunities to a full range of new services are given through barcode recognition in a Symbian OS based device. Therefore the purpose of this degree project was to create an application which would contribute to a future solution aimed at shopping where the cell phone constitutes a reader of items? identification numbers.

"Det finns inte en cell i min kropp som vill ha barn!" : En fenomenologisk fallstudie av en kvinnas upplevelser av att vara barnfri

Idag är forskningen kring barnfrihet till skillnad från barnlöshet begränsad och beskrivningar kring upplevelser av fenomenet barnfrihet beskrivs sällan. Vi kan dock hitta litteratur som beskriver en komplexitet i valet av att som kvinna välja barnfrihet, vilket vi i denna studie närmare beskriver utifrån en kvinnas upplevelser samt erfarenheter. Syftet med denna studie är att undersöka en kvinnas upplevelser kring valet av att vara barnfri. Detta syfte har vi kunnat nå genom att göra en fenomenologisk fallstudie där vi genom två intervjutillfällen med en kvinna kunnat få en djupgående berättelse om hennes upplevelser samt erfarenheter av att vara barnfri. Hon har under en lång tid varit säker på att hon inte vill ha barn och att det inte finns en cell i hennes kropp som vill det.

Optimization of Western Blot for detection of cellspecific localization of DNA binding protein fromstarved cells (Dps) in Nostoc punctiforme

Cyanobacteria belong to the oldest organisms of our planet. They use photosynthesis to produce ATP and gain biomass from carbon dioxide. The cyanobacteria Nostoc punctiforme is a filamentous bacterium that consists of two different types of cells, vegetative cells and heterocysts. The type of cell it differentiates into depends on the media they grow in. In an ammonium-rich medium, the N.punctiforme consists of vegetative cells that differentiate into heterocysts when in the medium is changed to a low-concentration ammonium medium.

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