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359 Uppsatser om Tumor initiating cell - Sida 4 av 24

Cutaneous Melanoma in the Grey Horse

Equine cutaneous melanomas arise much more often in horses with a grey coat color than in horses of other colors. Some scientists have in different studies come to the conclusion that the melanomas are neoplasms which can be classified by examining their histological and macroscopic features. The more defined and demarcated a tumor is, the more benign it tends to be. Other scientists believe that the skin lesions are the result of a pigmentation disorder that is linked to the greying of the coat color. According to this theory, the lesions are not malignant although they have the ability to metastasize.

Mobiltelefonen som social artefakt inom familjen : en studie med föräldrarna i fokus

Studies of modern communication media such as Cell Phones and so called Instant Messengers are popular today. This study focused on these modern techniques, focused on parents as a target group and on what is important for them in everyday communication.By exploratory using three focus groups it became clear that the children, and the link to them was the absolute most important thing for the parents. It became clear that this link to a great extent today exists through the mobile phone.In a following study a Mobile Instant Messenger called My Friends was introduced. It was used by two families during two weeks to see how it would change the communication within the family. The focus was to see how problems with availability were handled, it turned out that:My friends had a more obvious way of indicating availability than the Cell Phone had.

Hållbar energi : - Ett initiativ till utveckling av bränsleceller i Sverige

In the world we live in today the environmental issues has become increasingly important, and we have begun to realize that we can not continue to use fossil fuels at the rate we do. When it comes to generating electricity we are constantly trying to come up with cleaner and more efficient solutions. The fuel celltechnology is one such alternative and has been around for over 100 years. Yet, it is not until now that the world has started to notice this great technology. The fuel cell has been developed in several areas and can today be used for handheld electronics, vehicles and small settlements.

Mekanismer för inaktivering av lipoproteinlipas i 3T3-L1 celler : En studie av hur aktiviteten regleras med Angiopoietin-likt protein 4, Actinomycin D och Tumor Necrosis Factor alpha

Denna studie undersöker hur stressfaktorer påverkar kroppen vid dykning i gruva. Undersökningen genomfördes under en helgs intensivt dykande, för att bestämma lungkapacitet, pulsnivå samt eventuell vätske- och viktförlust hos dykarna. Testerna bestod av vägning, spirometritester och pulsmätningar. Testpersonerna dök mellan ett till tre dyk under helgen. Två av det totala antalet dyk var på 74 meters djup, resterande dyk genomfördes på 36 meters djup.

Samband på individnivå mellan akuta klövskador och cellhalten i mjölk hos mjölkkor :

The purpose of the present study was to investigate the cow-level association between acute hoof lesions and the somatic milk cell count in dairy cattle. Cows from three loose-housed Swedish dairy herds were enrolled in the study if they had an acute hoof lesion treated by a veterinarian or professional hoof trimmer during the preceding year, according to farmer records. Studied lesions were sole ulcer, dermatitis, interdigital necrobacillosis and hoof abscess, in each case causing lameness. For each hoof-diseased cow, 0 to 3 healthy cows were included, matched with respect to herd, breed, parity and lactation stage. Cell counts were obtained from monthly test recordings from one month before to three months after the hoof-lesion diagnosis, and log-transformed.

Effektivisering och produktivitetsökning i produktionsflödet av Hammarhäftare på Isaberg Rapid AB

AbstractThe market?s demand to purchase more cost effective products is continuously increasing. The producers are forced to become more efficient and flexible with resources to produce high quality products at a low cost in order to maintain or increase market shares. With this in mind Isaberg Rapid AB is requesting a project to increase efficiency in the assembly cell of hammertackers. The company has found in Kaizen-events that there is a potential of efficiency improvements in the assembly group that has not been achieved.The objective with this paper is to identify the major factors that influence the efficiency in the assembly cell for hammertackers.

Utveckling av mobilapplikation

The company System Andersson is developing systems for controlling materials and production in industries. They want to add a new service, where parts of those systems are accessible through cell phones.In this paper we are investigating which technology are best suited for this kind of application. And then we describe how we are developing a prototype fort this application, based upon that technology. After investigating technologies such as Java ME, Microsoft Silverlight, and web applications we settled upon building the system as a web application, customized for a mobile environment.To build a web page which is readable by many different cell phones we use the markup-languages which are developed for cell phones. We put much effort in reading about the standards and recommendations for the mobile web, produced by the organizations W3C and OMA.

Augmented Reality i mobiltelefonen : En kunskapssammanställning med trafikinriktning

This master thesis is about Augmented Reality (AR), a phenomenon that has existed since the mid-fifties but only recently has become available for the general public. This report is a knowledge compilation about AR, focusing on AR in cell phones and the use of the technology in traffic related situations.AR is usually described as adding a digital layer of information onto the real world. There are different technologies to make virtual images; in cell phones sensor-based and camera-based technologies are the most common ones.In this report, the market of AR applications for cell phones has been investigated. Three use cases have also been investigated in order to get more knowledge about the designers' thoughts and visions.In order to analyze the technology and the applications in a broader and more scientific perspective, two theories has been used: Situation Awareness (SA) and the Service Dominant Logic (SDL). These theories seem useful when reflecting on the Swedish road administrations vision, and to investigate what the applications and the AR technology can contribute to the traffic domain.The conclusions of this thesis are that:- AR can be applied on most of the human senses, but augmenting by visualization is most common.- The market for cell phone applications is growing rapidly: AR applications are relatively new but on the rise.

Impulsmätning medelst gradvis deflektion av alla sprayer från högtrycks common rail spridare

A method for measuring the total impulse from a multi hole diesel injector, introduced inprevious thesis work, ?Development of a method and a device for measuring the momentumrate of fuel sprays?, by Mikael Lindström, has been further developed and tested. The conceptis to simultaneously deflect all sprays from a multi hole diesel injector by using a bell shapeddeflector. The fuel sprays are deflected straight down from their initial umbrella angle, andthe resulting deflection force is measured in a thin strained section of the load cell. The strainis given by three strain gauges, with quarter-bridge circuitry for each gauge.

Prion infection of ovine cell culture with a natural Swedish scrapie isolate from 1986

Scrapie is an infectious neurologic disease in sheep caused by prions, corresponding to transmissible spongiform encephalopathies (TSEs) in other species. The prion is presumably constituted of PrPSc, the misfolded form of the normal endogenous prion protein, PrPC, which is found in practically all cells in the body. PrPSc can induce a conformational change in PrPC and misfold it as an imprint of itself; this is how prions amplify and spread. The process of conformational change is poorly understood and there might exist intermediate forms between PrPC and PrPSc. Bioassay using mice has traditionally been the golden standard in prion studies but is limited by cost and time.

Förstudie för automatisering av gjutgodsrensning

This thesis work has been performed at the Division of Assembly Technology at Linköping University for a period of ten weeks. The work is part of the project ProFlexA, which is a research project in collaboration between Linköping University, Lund University, and industrial partners such as Combi Wear Parts and Smålands Stålgjuteri AB.The casting process creates random incurred burrs and defects, which must be removed during a cleaning process to make sure that the cast can be sold. Automation has long been sought for the cleaning of castings due to, among other things, poor working conditions for staff, but this has proved difficult to implement with today's technology. Automation has for some time been available for more capital strong companies with large annual volumes, but for smaller companies with small-and medium-sized volumes, automation has not been an option.The goal of ProFlexA is to develop an automated cleaning cell aimed at small-and medium-sized volumes.The goal of the thesis is to do a pre study at ProFlexA?s partners on cleaning of castings, and develop concepts for automated cleaning of castings.By recording the process and cycle times, the cleaning of castings has been documented as it works today, and on this basis, information and statistics has been compiled.

Stokastiska processer f?r modellering av cellpopulationer: Simulerad cell?ldrande och f?ryngring p? populationsniv?

I den h?r rapporten till?mpas tv? f?rgreningsprocesser, en diskret tid Galton-Watson och en kontinuerlig tid Markov f?rgreningsprocess, i syfte att studera hur en population av ?ldrande celler utvecklas beroende p? populationens celldelningsf?rm?ga och delningshastighet, d?r ?ldrandet ?r direkt kopplat till ackumulering av defekta proteiner. Vi kollar ?ven p? effekten hos cellens ?ldrande baserat p? hur k?nsliga de ?r f?r defekta proteiner. Populationens delningsf?rm?ga har en avg?rande effekt p? hur v?l populationen v?xer och bibeh?ller ett l?gre antal defekta proteiner hos cellerna, med dessa f?ruts?ttningar ses ytterligare effekt baserat p? delnigshastigheten hos cellerna.

Analysis of CD4+ and CD8+ T-lymphocytes : A comparison between EPICS XL and Celldyn Sapphire

Flowcytometric technology has been widely used for measurement of the absolute numbers of T-lymphocytes subsets in Human Immunodeficiency virus (HIV), defining the disease state, monitoring antiviral treatment, and identifying any risk for opportunistic infections. A manual preparing of the samples is required. More recently an automated and enclosed blood cell counting, Celldyn Sapphire has been introduced. In this study the performance of the Flow cytometer EPICS XL as a reference method for analysis of CD3+, CD4+ and CD8 T-lymphocytes was evaluated with blood from 40 individual?s samples.

Optimization of Lentivirus Production for Cancer Therapy

Vectors based on lentivirus backbones have revolutionized our ability to transfer genesinto many cell types. Lentiviral vectors integrate into the chromatin of target cells and do not transfer any viral genes causing vector replication. Both of these features arecommonly used in gene therapy and have been used clinically in individuals sufferingfrom cancer, infections and genetic diseases. It has been discovered that T-cells can be genetically modified to be used as effective weapons against cancer: therefore virus mustbe produced to deliver the gene of interest into the T-cells. In this project, lentiviralvectors have been produced to transfer the gene coding for a chimeric antigen receptor(CAR) which is directed to CD19 on B-cells.

Small scale dairy farming in Zambia

Milk yield levels in dairy cows are influenced by many factors such as nutrition, breed, health status, management and environment. This study was conducted among small scale farmers in Zambia, where the climate can be dry for up to six months per year and cause a lack of green pasture for livestock and on-farm produced feed. The purpose of this study was to identify management factors that can influence milk yield at small scale dairy farms in Zambia, and present advice that could improve productivity, without the need of expensive investments. The study included semi-structured questionnaires presented to the farmers (n=29) including questions about cattle management and milk production. Testing of somatic cell count (SCC) with DCC (DeLaval Cell Counter) from herd milk samples (n=56) and observation of housing and animal body condition on-farm was also made.

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