Celiac disease (CD) is an autoimmune disease, induced by an immune mediated reaction in the small intestine after ingestion of gluten and related prolamines. There is a strong genetic linkage and most important are the genes that encodes for HLA-DQ2 and HLA-DQ8. The European Society for Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN) has developed new guidelines for investigation of CD in children and adolescents, which include genotyping for HLA-DQ2 and HLA-DQ8. Therefore, the clinical microbiological laboratory in Västmanland wants to introduce a method for analysis of these genes. Microarray is a newly developed method for determination of the alleles HLA-DQA1 and HLA-DQB1 that encodes for the ?- and ?-subunits of the HLA-molecules.

Celiac disease (CD) is an autoimmune disease, induced by an immune mediated reaction in the small intestine after ingestion of gluten and related prolamines. There is a strong genetic linkage and most important are the genes that encodes for HLA-DQ2 and HLA-DQ8. The European Society for Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN) has developed new guidelines for investigation of CD in children and adolescents, which include genotyping for HLA-DQ2 and HLA-DQ8. Therefore, the clinical microbiological laboratory in Västmanland wants to introduce a method for analysis of these genes. Microarray is a newly developed method for determination of the alleles HLA-DQA1 and HLA-DQB1 that encodes for the ?- and ?-subunits of the HLA-molecules.

This research overview examines what research says about upper secondary school students' difficulties with complex numbers. The three main areas covered are general difficulties with complex numbers, how to teach the subject, and whether the history of complex numbers can be beneficial in this teaching. A historical deep dive into the history of complex numbers is also included to further investigate this idea. The results show that upper secondary school students struggle with complex numbers in various ways. The name of the subject creates a negative connotation, as it is initially perceived by students as fictional and complicated. Furthermore, a consequence of the inherently abstract nature of complex numbers is that gaining a comprehensive understanding of them is challenging.

Under dräktigheten modulerar embryot stoets immunförsvar på flera sätt för att undvika att stötas bort. Embryots invasiva trofoblaster är de enda trofoblaster som uttrycker så kallade major histocompatibility complex class I (MHC I). Invasiva trofoblaster bildar endometrial cups och därefter nedregleras MHC I, vilket bedöms vara viktigt för embryots fortlevnad. Endometrial cups utsöndrar även immunsupprimerande faktorer och kan påverka de maternella cellernas cytokinuttryck på flera sätt. Delade meningar råder om huruvida stoets immunförsvar går mot ett cellmedierat eller antikroppsmedierat svar under dräktighet.

Virulent strains of Staphylococcus hyicus produce exfoliative toxins and cause a potentially fatal skin disease in piglets known as exudative epidermitis. Vaccines and antimicrobials are used to control the disease. Antimicrobial resistance and the prevalence of several different toxin genes and toxigenic strains make it problematic. The aim of this literature study was to identify potential differences between countries and between healthy and diseased pigs regarding antimicrobial resistance and toxin-producing strains. Great differences could influence vaccine production, treatment strategies and surveillance programs.

Virulent strains of Staphylococcus hyicus produce exfoliative toxins and cause a potentially fatal skin disease in piglets known as exudative epidermitis. Vaccines and antimicrobials are used to control the disease. Antimicrobial resistance and the prevalence of several different toxin genes and toxigenic strains make it problematic. The aim of this literature study was to identify potential differences between countries and between healthy and diseased pigs regarding antimicrobial resistance and toxin-producing strains. Great differences could influence vaccine production, treatment strategies and surveillance programs.

The Swedish Red Polled breed is threatened by extinction and there are only around 1100 animals left. The breed was popular in the early twentieth century, but since then the numbers have steadily decreased. The overall objective of this study was to find out whether there may be economic incentives for preserving the breed. The milk quality properties are of major importance in the production of dairy products. Therefore we would like to establish if the Swedish Red Polled breed carries favourable alleles at loci of relevance for milk quality, to potentially make the breed more interesting for milk production.

Purpose: To analyze and clarify differences between indie and major labels in the use of and attitude towards the Internet as a marketing and distribution channel.Method: In this study, we use mostly qualitative but also quantitative methods. Representatives from four record labels, two indie and two major labels have been interviewed, and we have also examined the companies? activities on the Internet.Conclusions: This study points to a number of differences between indie and major labels. Indie labels are generally more open to business development and innovation. As for marketing, indie labels make use of web services such as Myspace and Facebook to a greater extent than major labels.

Mammary tumors are the most frequent type of tumors in bitches in Sweden. Many studies have been published concerning mammary tumors, but there is still much to be learned about this disease. One has, since some time ago, had the knowledge that addition to or removal of methyl groups to genes can inhibit or activate gene-expression. Methylation and demethylation is a normal phenomenon in the body and it is essential for the development and survival of the individual. The risk of developing a tumor disease is increased if the global methylationstatus is changed; if oncogenes demethylates (activates) or if tumor suppressor genes methylates (inactivates). In the human medicine one has seen that there are differences in methylationstatus between different tumors. In this study tumor and normal tissue from ten dogs were examined with regard to methylationstatus.

Purpose The purpose of this study is to evaluate the treatment results and adverse drug effects for 14 dogs receiving a new paclitaxel preparat named Paccal vet. The evaluated dogs are chosen to enter a pharmacogenomical study. Therefore, this paper intends to give an introduction to pharmacogenomics. Finally this study also aims at finding the homologue genesequenses in dogs to seven genes that are important for metabolism of paclitaxel in humans. Materials and metods The dogs went through 2-4 cycles of paclitaxel treatment, they received a new water-soluble formula named Paccal vet, at dosages of 100-150mg/m2. Treatment results and adverse effects are listed for each dog in table 1.

The city is complex, multi-faceted and fascinating. The same can be said about the rooms of the city. The experience of the rooms of the city can be described in as many ways as there are individuals. The question concerned in this essay is How can you describe the rooms of the city as a phenomenon and how can you describe the experience of these rooms in general? The concepts city and room are widely understood and neither of them has a description that can be used in all situations.

An organism that is transferred from one place to another, causing major problems to the native species is termed invasive. Its natural dispersal across barriers may have been prevented but as man has turned able to rapidly travel all over the world organisms are brought to sites where they were never before observed. Adding the increasing global warming organisms may find it necessary to move around even further. This might cause major disturbance to the biological diversity, and hybridization and homogenization is one of many scenarios that could disturb the native diversity. In Sweden more that 2/3 of all alien plant species have been introduced to disturbed areas and the major introduction mechanism is gardening.

Purpose The purpose of this study is to explain what possibilities the new license between Youtube and Stim can have for Swedish artists and what impact this may have for the Swedish major record labels? competitive advantage. Based on this, the aim is also to describe how artists' position of power against major record labels may change due to the license.Method The essay is based on an inductive approach. The authors have used a qualitative research method to gain a deeper understanding of the phenomenon investigated. Primary sources have been collected using a variety of interviews from different parts of the Swedish music industry.Conclusion The Swedish major labels still hold a strong position today both when it comes to power balance and attractiveness.

The response to many on-going or emerging conflicts since the beginning of the 21st century has been different forms of multinational complex peace operations. Civil-military relations are a commonly studied field that traditionally has its focus on nations. This study intends, in the context of organisations, to test the correlation between a civil-military approach and outcome in complex peace operations. A hypothesis has been deduced from researcher Robert Egnell?s theory on complex peace operations, that states that: UN peace operations with an integrated civil-military approach are more successful in achieving their goals than peace operations with a divided approach.

The area of Lycksabäcken northwest of Lycksele is a national interest of natural conservationbecause of its geological values with many unique landforms. Many of these landforms indicatethat the deglaciation process in the area was very complex. However, the deglaciation process inthe area has not previously been fully understood. The aim is to add to the knowledge of theevents that took place during the last deglaciation. To do this, the glaciofluvial landforms in thearea were mapped by studying aerial photographs with a Wild Aviopreter and a five-day fieldinventory of key areas for the interpretation.