Introduction The genetic skin disease epidermolytic ichtyosis is caused by mutations in either keratin gene 1 or 10 and leads to blisters and hyperkeratosis of the epidermis. At cellular level the disease is seen as aggregates in the keratin filaments. Since medicines are hard to investigate and produce mainly due to lack of reproducible model systems, there is no good treatment available for this disease today. In this article we describe how an in vitro model consisting of cells from a stable cell line transfected with expression plasmids to mimic patient cells, may be a possible alternative for screening compounds for therapies. The first step was to generate an expression plasmid required to complete the in vitro model.

The aims of the study were to investigate the prevalence and antibiotic resistance of Campylobacter jejuni and Campylobacter coli in chicken and chicken products, and to investigate farmer awareness of antibiotic resistance development. The study was conducted in the Can Tho province in Vietnam during six weeks in October to November 2008. Ninety-six samples from raw chickens were collected from twelve market places and analysed for the presence of Campylobacter. A total of 96 cloacal swabs from 20 farms were obtained and analysed for the presence of Campylobacter. Farmers were asked to answer eight questions concerning the housing of the chickens, modes of handling sick animals as well as use and knowledge of antibiotics and resistance development to antibiotics.

Chemical Substances are spread diffusely and uncontrollably as a result of the increased consumption of goods. REVAQ is a certification system that works to reduce the flow of hazardous Substances to Swedish treatment plants and to create a sustainable nutrient recycling. According to REVAQ, the yearly accumulating rate of metals should not exceed 0.2% in soil per year. Silver and bismuth are two metals that do not fulfill this requirement. The silver concentration in sludge decreased during the last decade, however the last few years, it has leveled off.

SammanfattningSyftet med denna kvalitativa studie är att undersöka klienters erfarenheter av två former av missbruksvård. De undersökta verksamheterna är Alkohol- och narkotikagruppen, vilket är en öppenvårdsverksamhet i Lindesberg, samt Stiftelsen Bergslagsgårdar i Örebro, som bland annat arbetar med familjehemsvård för vuxna.Intervjuer har utförts med åtta klienter mellan 25 till 58 år, varav fyra berördes från varje verksamhet. Den kontextuella missbruksbakgrunden var varierad.Den semistrukturerade intervjuguiden har utformats utifrån studiens syfte, frågeställningar och tolkningsram. De teoretiska utgångspunkter som tillämpats är identitet, social värld samt copingstrategier. Tidigare forskning har studerats inom missbruksvård, motivation, tvång och frivillighet samt vilka nyckelingredienserna är för en lyckad missbruksvård. Resultat och analys har uppdelats i tre teman: 1)      Synpunkter på vården,2)      Upprätthållande av missbruksfrihet3)      Social tillhörighet och förändring. Resultatet indikerar en genomgående positiv inställning hos klienterna till vårdformerna och att motivationen är viktig för resultatet av vården.

Designing temporary cities is a study of the design and physical planning of five temporary cities. The purpose was to discuss and note the important questions to be considered, when designing the outdoor environment in temporary cities to create as good an environment for the visitor as possible. The five cities I have chosen are among the most famous ones in Scandinavia, and they represent different kinds of temporary cities. This was a deliberate choice to achieve diverse research material, and with that a broad view of what the planning stage generally looks like. Study of the cities has been done through interviews with the people responsible for the design and/or physical planning of each city.

Bakgrund: Tidigare forskning visade på att sjuksköterskor tenderade att ha en negativ bild av missbrukare, samtidigt som de uttryckte att de ändå gav god omvårdnad. Missbrukspatienterna ansågs ha ett stort eget ansvar för sin sjukdom. De negativa attityderna sågs ofta som direkt orsakade av kunskapsbrist. Syfte: Syftet med denna studie var att beskriva hur några sjuksköterskor uppfattade mötet med missbrukare på en akutmottagning i en svensk storstad. Metod: Intervjustudie med kvalitativ ansats, där det manifesta innehållet analyserades.

Previous research and patient complaints to the Swedish Patient Support Committee shows that there is a lack of Substance in the patient-nurse relationship. This may suggest that it can be difficult for health care to live up to health-care law which requires it to be of good quality, based on dignity and respect and designed so that the patient is an active participant and can make their own decisions when it comes to their health care. For a better understanding of what a dignified patient-nurse relationship is, this study aims to clarify what the patient values as good patient-nurse relationship and describe how they have experienced the patient-nurse relationship during their stay at an emergency care department. The study is a descriptive cross-sectional study with a quantitative approach, where the population consisted of patients who were cared for at an emergency care department in the County of Västmanland, Sweden during 2007. The sample consisted of 93 patients which were asked to answer a questionnaire.

Bakgrund: Substansberoende är ett växande folkhälsoproblem som kräver allt större resurser i dagens hälso- och sjukvård. Detta leder till att dagens sjuksköterskor möter personer med substansberoende i större utsträckning än tidigare. Sjuksköterskeutbildningen omfattar oftast inte kunskap om substansberoende och studier visar att bristande kunskap kan påverka personalens attityder till olika patientgrupper vilket i sin tur kan påverka både den givna vården och vårdmötet. Syfte: Syftet med studien var att belysa vilka attityder sjuksköterskor kan ha till att vårda personer med substansberoende inom somatiska vårdmiljöer. Metod: Studien är en litteraturöversikt, som utifrån tidigare forskning, belyser sjuksköterskors attityder till att vårda personer med substansberoende.

Tva?ngsva?rden av missbrukare a?r ett av samha?llets sista verktyg fo?r att va?rda missbrukare som lever ett va?ldigt destruktivt och farligt liv. Tva?ngsva?rdslagstiftningen har kritiserats fo?r att vara sva?rtolkad, och det finns sto?d fo?r att lagstiftningen tilla?mpas olika i landets socialna?mnder. Genom att intervjua socialtja?nstens enhetschefer om deras tolkning och tilla?mpning av tva?ngsva?rdslagstiftningen syftar uppsatsen till att belysa skillnader och likheter i tolkning och tilla?mpning av lagstiftningen samt att bidra med kunskap om vilka faktorer som kan fo?rsva?ra arbetet.

Public concern about the release of toxic compounds from wood-based products drives legislation towards enforcing industries to find and use more sustainable solutions for wood treatment. Plant oils are good alternatives to treat wood, minimizing or even neutralizing the impact on the environment. Wood modification with epoxidised linseed oil (ELO) and acetic acid as catalyst has proven a suitable method to impregnate and protect wood. However, the mixture presents a serious inconvenience because of the quick polymerization of the ingredients that limits its practical application. Therefore, this study was designed to evaluate an alternative method using a two-step process which bypassed the problem above.

Studiens syfte är att undersöka insatsers utfall för missbruksklienter efter avslutad vistelse på behandlingshem/ familjehem. Ett delsyfte är också att undersöka några variablers inverkan på utfallet samt hur dokumentationen ser ut. Utifrån detta har vi formulerat följande frågeställningar. (1) Hur har insatserna utfallit i stort? (2) Hur har sociala relationer beskrivits i anslutning till detta? (3) Hur har klientens delaktighet och motivation beskrivits? (4) Hur har den samlade dokumentationen av insatserna fungerat? För att besvara dessa har 14 akter studerats, metoden har varit såväl kvalitativ som kvantitativ.

Studiens syfte var att undersöka om naturläkemedlet Ibogain kunde vara en bra behandling för missbruk. För att kunna besvara detta har kvalitativa intervjuer genomförts med fyra personer som genomgått Ibogain-behandling och en psykolog/psykoterapeut på en beroendeklink, Lars Lundell. Utöver dessa intervjuer har en klinik i London besökts som utför Ibogain-behandling. På kliniken gjordes en observationsstudie av behandlingen, samt intervjuer med klinikchefen Dr Brackenridge och en av hans patienter, i uppsatsen kallad Will. Studiens perspektiv utgår från informanterna och våra egna observationer om Ibogain-behandling.

The aim of this paper is to elucidate and analyze history teacher's didactic choices in the conflict between unequal educational materials and the requirements of equality in the curriculum of Swedish secondary school. The empirical data consists of interviews with five secondary school history teachers, observations of their lessons as well as analysis of their tests. The starting point was to investigate teachers' didactic work in the role as a bridge between the non-equal historiography presented in textbooks in history and the curriculum?s demands for equality. Three different approaches have been observed in the teachers' didactic work when considering gender perspective into their teaching: that women become extensions in a male-dominated historiography; that another part of the story is presented when a gender perspective is considered; and that the gender perspective is included in history teaching and becomes an integral part of all the content of the subject.Several of the teachers acknowledged that gender equality is less prioritized than the courses core content and related assessment criteria.

Deep litter is a system for animals kept in separate stalls, loafing and bedding in wind shelters. The litter can consist of different bedding, like straw and peat. The system is allowed to build over and to ensure optimal proportions it is necessary to add new straw regularly and to have good conditions. Important conditions are aerobic state, humidity, amount of organic Substance and acceptable temperatures in the litter. The micro organisms are depending on temperature for their living conditions and to get the bottom layer in the litter to start burning.

The aims of the study were to investigate the prevalence and antibiotic resistance of Campylobacter jejuni and Campylobacter coli in chicken and chicken products, and to investigate farmer awareness of antibiotic resistance development. The study was conducted in the Can Tho province in Vietnam during six weeks in October to November 2008. Ninety-six samples from raw chickens were collected from twelve market places and analysed for the presence of Campylobacter. A total of 96 cloacal swabs from 20 farms were obtained and analysed for the presence of Campylobacter. Farmers were asked to answer eight questions concerning the housing of the chickens, modes of handling sick animals as well as use and knowledge of antibiotics and resistance development to antibiotics.