Diabetes mellitus is a rising epidemic throughout the world and there is currently great interest in quantifying the beta-cell mass (BCM) in vivo non-invasively. In the present experiment, the feasibility of in vivo imaging of the glucagon-like peptide-1 receptor (GLP-1R) in beta-cells was examined, using the positron emission tomography (PET) tracer [68Ga]Ga-DO3A-VS-Cys40-exendin-4 as a marker, in native pancreatic beta-cells of a porcine diabetic animal model and healthy controls. Eight Swedish high-health domestic pigs were randomly assigned to be either controls or made diabetic using streptozotocin (STZ). The experiment proceeded during eight weeks, starting with an acclimatisation period. Once the pigs had been socialised they underwent surgery for the insertion of a jugular vein catheter, allowing induction of diabetes with STZ, intravenous (i.v.) injections and stress-free blood sampling. Development of diabetes was confirmed by clinical examinations, blood glucose values and insulin-staining of pancreatic sections post mortem. The diabetic pigs were insulin treated and responded well.

This work is about the rights of children, how students use social media and how effective teachers are using social media in their work against abusive treatment. The purpose of this work is to examine what students have rights in school, what and how students use social media and how schools and teachers are working to prevent the abuse that takes place over the internet and via mobile phones. The method used to investigate this is partly a survey of students in grades five and six at four different schools and interviews with four practicing teachers, working as a teacher in each class who made survey. My conclusion is that children have a variety of rights in school, and all schools and teachers are working on this through rules, values ??clarification and collaborative exercises. More and more younger children use out of social media, the survey shows that many of the students in grades five and six uses much social media.

Introduction The genetic skin disease epidermolytic ichtyosis is caused by mutations in either keratin gene 1 or 10 and leads to blisters and hyperkeratosis of the epidermis. At cellular level the disease is seen as aggregates in the keratin filaments. Since medicines are hard to investigate and produce mainly due to lack of reproducible model systems, there is no good treatment available for this disease today. In this article we describe how an in vitro model consisting of cells from a stable cell line transfected with expression plasmids to mimic patient cells, may be a possible alternative for screening compounds for therapies. The first step was to generate an expression plasmid required to complete the in vitro model.

The aims of the study were to investigate the prevalence and antibiotic resistance of Campylobacter jejuni and Campylobacter coli in chicken and chicken products, and to investigate farmer awareness of antibiotic resistance development. The study was conducted in the Can Tho province in Vietnam during six weeks in October to November 2008. Ninety-six samples from raw chickens were collected from twelve market places and analysed for the presence of Campylobacter. A total of 96 cloacal swabs from 20 farms were obtained and analysed for the presence of Campylobacter. Farmers were asked to answer eight questions concerning the housing of the chickens, modes of handling sick animals as well as use and knowledge of antibiotics and resistance development to antibiotics.

Chemical substances are spread diffusely and uncontrollably as a result of the increased consumption of goods. REVAQ is a certification system that works to reduce the flow of hazardous substances to Swedish treatment plants and to create a sustainable nutrient recycling. According to REVAQ, the yearly accumulating rate of metals should not exceed 0.2% in soil per year. Silver and bismuth are two metals that do not fulfill this requirement. The silver concentration in sludge decreased during the last decade, however the last few years, it has leveled off.

ABSTRACTIn this study, five people were interviewed who are involved in a drug-assisted program for opiate addiction, also called substitution program. The meaning of substitution is that these clients' drug addiction is replaced with substitute preparations, either methadone or Subutex in an orderly manner. The clients of the researcher decided to study the substitution program have all been a heavy opiate addiction for years. Their participation in the replacement program is more than two years, and those who have been around the longest have been in the program for six years, so long as the substitution program has existed in Visby.This is a qualitative study in which interviews are conducted face to face with each individual client, and the interview was unstructured in the sense that no specific issues made in advance. The interviews have been themed, and the researcher has gone through various areas of life around the respondent.

The purpose of this work was to research how baby nurses define the concept child maltreatment and how they conduct themselves to mandatory reporting.The central questions were; How do the baby nurses interpret the concept child maltreatment and which children do they consider comprehending the concept?What are the reasons that children are maltreated according to the baby nurses opinions?Do the baby nurses apprehend that they meet children that are maltreated in their work?How do the baby nurses interpret the mandatory reporting and what course of action do they use when they suspect child maltreatment?Nine baby nurses were interviewed. The material was analyzed with the help of a phenomenological method.The participators idea of the concept child maltreatment was focused on observing signs from the child and concrete actions from the parents. The outcome of this concept is that the participators categorization is neither or nor. The participators knew about the mandatory reporting and they did a further interpretation because they focused on the risk of the child.

Sverige har en lagstadgad anmälningsplikt som är obligatorisk för alla som i sitt arbete kommer i kontakt med barn. Lagen är tydlig med att alla misstänka missförhållanden skall anmälas. Forskning visar att anmälningsplikten inte alltid fungerar och att det bara är en liten del av de barn som riskerar att fara illa som kommer till socialtjänstens kännedom. Vidare forskning visar att få anmälningar kommer från hälso- och sjukvården. Syftet var att beskriva sjuksköterskans erfarenheter i mötet med barn som far illa eller riskerar att fara illa.

Designing temporary cities is a study of the design and physical planning of five temporary cities. The purpose was to discuss and note the important questions to be considered, when designing the outdoor environment in temporary cities to create as good an environment for the visitor as possible. The five cities I have chosen are among the most famous ones in Scandinavia, and they represent different kinds of temporary cities. This was a deliberate choice to achieve diverse research material, and with that a broad view of what the planning stage generally looks like. Study of the cities has been done through interviews with the people responsible for the design and/or physical planning of each city.

Bakgrund: Tidigare forskning visade på att sjuksköterskor tenderade att ha en negativ bild av missbrukare, samtidigt som de uttryckte att de ändå gav god omvårdnad. Missbrukspatienterna ansågs ha ett stort eget ansvar för sin sjukdom. De negativa attityderna sågs ofta som direkt orsakade av kunskapsbrist. Syfte: Syftet med denna studie var att beskriva hur några sjuksköterskor uppfattade mötet med missbrukare på en akutmottagning i en svensk storstad. Metod: Intervjustudie med kvalitativ ansats, där det manifesta innehållet analyserades.

Föreliggande studie har för avsikt att ta reda på hur samarbetet mellan de inblandade instanserna ser ut, vid brott gällande sexuellt utnyttjande av barn under femton år. Studien fokuserar på rättsprocessen och informanternas upplevelser i samband med samarbetet mellan myndigheter, resurser och barnkonventionen. Samarbetet analyseras med hjälp av Max Webers sociala handlingar, aktör och struktur, makt och maktresurs, institutionalisering, kyrkan och kristendomen som institution och nya testamentet.Frågeställningen är: Hur upplever intervjupersonerna utredningsprocessen? Hur upplever intervjupersonerna samarbetet mellan de inblandade instanserna? Vilka svårigheter identifieras utav respondenterna i processen? Hur beskrivs arbetet med barnkonventionen utifrån respektive intervjuperson? Hur anser intervjupersonerna att sexuella övergrepp mot barn prioriteras i samhället?En av slutsatserna är att samarbetet mellan instanserna inte är till belåtenhet och att samarbetet påverkas av vad respektive myndighet har för handlingsförmåga. Handlingsförmågan möjliggörs av organisationens handlingsstruktur som också är den som sätter ramarna utifrån de ekonomiska resurserna som finns att tillgå för arbetet..

Previous research and patient complaints to the Swedish Patient Support Committee shows that there is a lack of substance in the patient-nurse relationship. This may suggest that it can be difficult for health care to live up to health-care law which requires it to be of good quality, based on dignity and respect and designed so that the patient is an active participant and can make their own decisions when it comes to their health care. For a better understanding of what a dignified patient-nurse relationship is, this study aims to clarify what the patient values as good patient-nurse relationship and describe how they have experienced the patient-nurse relationship during their stay at an emergency care department. The study is a descriptive cross-sectional study with a quantitative approach, where the population consisted of patients who were cared for at an emergency care department in the County of Västmanland, Sweden during 2007. The sample consisted of 93 patients which were asked to answer a questionnaire.

Bakgrund: Substansberoende är ett växande folkhälsoproblem som kräver allt större resurser i dagens hälso- och sjukvård. Detta leder till att dagens sjuksköterskor möter personer med substansberoende i större utsträckning än tidigare. Sjuksköterskeutbildningen omfattar oftast inte kunskap om substansberoende och studier visar att bristande kunskap kan påverka personalens attityder till olika patientgrupper vilket i sin tur kan påverka både den givna vården och vårdmötet. Syfte: Syftet med studien var att belysa vilka attityder sjuksköterskor kan ha till att vårda personer med substansberoende inom somatiska vårdmiljöer. Metod: Studien är en litteraturöversikt, som utifrån tidigare forskning, belyser sjuksköterskors attityder till att vårda personer med substansberoende.

The purpose of the study is to examine what effects the law has on principals? approaches to mandatory reporting of child maltreatment (Social Services Act 14:1§). Moreover, the aim is to study if the regulation gets the impact intended. To respond to the purpose, legal science methods in the form of sociology of law were employed aided by qualitative semi-structured research interviews. The interviews comprised six principals in six different schools in the Stockholm area.

Purpose/Aim: This essay seeks to describe in what way different newspapers framed Uppsala Reggaefestival, which is a music festival in Uppsala, Sweden. Not only the local press, but also the framing by national press will be analyzed. Furthermore, it seeks to discuss what causes different frames.Material/Method: The material consist of 96 articles from 4 different newspapers which are being analyzed through a quantitative content analysis method inspired by Melin and Lange, and their ideas of identifying the main message of a text. The media framing of Uppsala Reggaefestival are compared to another similar music festival in Sweden, Arvikafestivalen. By using theories about media framing and media logic the results can, if not explained, at least be discussed.Main results: The study shows that Uppsala Reggaefestival is framed in a way that is focused on the problems within the festival, for example drug abuse.