Bakgrund: Läkemedelsbranschen är idag en av de mest reglerade branscherna på marknaden. Forskning och utveckling har en stor betydelse för läkemedelsföretagen. För att lansera ett läkemedel krävs det att företagen genomför kliniska prövningar, deras utfall kan mycket väl avgöra företagens framtid.Problemformulering: hur stor inverkan har de olika faserna inom produktutvecklingen på aktiekurserna för företag i läkemedelsbranschen.Syfte: Syftet med uppsatsen är att undersöka hur marknaden reagerar när läkemedel som är under utveckling går in i de tre olika kliniska faserna.Metod: Studien baseras på kvantitativ data där ett bekvämlighetsval gjorts på sju stycken läkemedelsföretag. PR meddelanden där läkemedel i utveckling går in i fas-1, fas-2 och fas-3 kliniska prövningar har valts ut som enskilda händelsen i eventstudien som genomförts. Vi har studerat vad som händer 5 dagar före och 5 dagar efter att händelsen utspelar sig.

This master?s thesis aims to study the practice of separating popular genres of fiction from the rest of the fiction stock, often seen at public libraries. The method being used is critical discourse analysis according to Norman Fairclough?s three-dimensional conception of discourse. The textual dimension of this analysis is the book shelf itself and the sociocultural practice is the everyday practice at a public library of supplying and mediating books to the visitors.

Background: Companies with a high level of research, such as biotech companies, rarely generates any profit in the begining. Mostly their history is short and their pipelines usually consists of one or a few products only. Significant for the line of business is also a future very uncertain, where relevant objects of comparison are few. Altogether the facts above makes valuation of Biotech companies difficult. Swedish Biotech companies, compared to their american competitors, seem to be of relatively low value.

SAMMANDRAGHistorisk Simulation, Delta-Normal och RiskMetrics prestation utvärderas med hjälp av Kupiecs Backtest. Value at Risk (VaR) beräknas med tre olika konfidensnivåer utifrån Affärsvärldens Generalindex och HSBC kopparindex. Utifrån överträdelser från verkligt utfall undersöks vilken VaR-modell som estimerar marknadsrisken bäst. VaR-modellernas prestation jämförs, och i analysen utreds hur konfidensnivå och tillgångars egenskaper påverkar VaR-modellernas prestation. Resultaten visar att Historisk Simulation presterar bättre än Delta-Normal och RiskMetrics på den högsta konfidensnivån vilket troligtvis beror på att RiskMetrics och Delta-Normal antar normalfördelning.

The purpose on this study is to determine the extent of possible connections between tendencies to increased violent behavior and increased alcohol consumption among a total cohort of girls in the 9th grade compulsory school and 2nd grade upper secondary school in a Swedish county. In 2004 the Epidemiological Department carried out a health-status survey, using a self-report questionnaire, with students from both private and public schools in a specific county in Sweden. All respondents (N= ca 4000), attending all compulsory (at 9th grade) and upper secondary schools (second tier) on the survey date completed the questionnaire. For this particular study, 9 questions from the questionnaire, all concerning self-reported violent behavior and alcohol consumption habits were used either individually or combined in index variables. The result showed that while violence experience is low among these 4000 girls, it increased in relation to a corresponding increase in alcohol consumption.

En fallstudie tillämpades för att undersöka de inbyggda apparna, Internet Explorer 10, den nya utforskaren File Explorer och reparationsverktyget ?Återställ datorn utan att ta bort filer? i Windows 8. Analysen visade att apparna E-post, Kontakter och Meddelanden sparade större delar av användarens Facebook-profil lokalt på datorns hårddisk. När bildfiler öppnades upp med appen Foton sparades miniatyrbilder av originalet på hårddisken. När videofiler spelades upp med appen Video sparades filnamnet i filer.

I detta examensarbete evalueras brandsäkerheten på gruppboendena Maskrosen och Ventilen samt äldreboendena Smedsberget och Skytten i Lycksele stad. Arbetet är utfört på uppdrag av räddningstjänsten i Lycksele kommun. För att få en tillförlitlig bedömning av de fyra boendena har projektgruppen valt att använda sig av programmet ?Brandskyddsvärdering av vårdavdelningar? (BSV-vård). Detta program är baserat på olika komponenter vilka viktas med en viktningsgrad och sedan slås samman för att ge ett slutgiltigt Brandskyddsindex.

The castle Vivesholm is located about two miles north of Klintehamn on the west side of Gotland. The castle was built around year 1395 and burned down in the end of the 14thcentury. Around the 17th and the 18th century the castle was re-used. However, the emphasis on its use is during the middle ages.This paper aims at getting an insight in the animal husbandry at Vivesholm by analyzing the osteological material. The analysis revealed that bones from sheep/goat were more common than bones from cattle.

Voltage sag indices are a way of quantifying the performance of the power supply, as far as voltage sags are concerned. Indices can be defined for individual events, for individual sites, and for a whole system. A standard method for single-event methods is part of IEC standard 61000-4-30.This thesis emphasizes the importance of voltage sag indices and different methods for calculating three-phase voltage sag characteristics. Three-phase events measured in a medium network voltage over period of one month were analyzed, results examined and statistically evaluated. An algorithm for calculating voltage sag characteristics and indices was created in Matlab.

The purpose of this study was to investigate patients self-rated ADL-function after a periprosthetic fracture, to view the demographics of the patient group and investigate any gender differences in ADL-function. Whether patients managed to return to previous housing after the fracture and reasons for this was also studied.This is a register-based retrospective and prospective cohort study with a quantitative approach. Demographic and anamnestic patient data was collected from the electronic health records. The participants were called for an interview where Katz ADL-index and EQ5D was used to describe the participants´ ADL functioning together with physical and mental functioning.The result shows that the majority of the participants rated themselves as independent in their ADL-function. No gender differences were noted in ADL-functioning.

Äldre patienter som har risk för undernäring eller är undernärda är vanligt förekommande på svenska sjukhus. Syftet med denna litteraturstudie var att beskriva vad sjuksköterskan kan göra för att förebygga undernäring hos äldre patienter (65+) på sjukhus. En beskrivande litteraturstudie genomfördes där författarna granskade elva vetenskapliga artiklar. Artiklarna söktes i databaserna PubMed och Mosby´s index. Resultatet i studien visade att det finns flera olika mätmetoder för att upptäcka undernäring eller risk för undernäring hos äldre patienter inneliggande på sjukhus.

The waste of material is a big expense for manufacture companies caused by lack of quality. The cost by lack of quality often totaled to a big percentage share of the turnover when all cost related to lack of quality is included. New manufacturing systems like Lean production or Just In Time demands better internal quality for the manufacturer. To make those manufacturing system with small and none buffer stock successful the quality improvement continuously have to be developed.Measuring of waste of material in Bubs Candy?s factory where not simple due to the products does not have a permanent weight during the manufacturing process.

Sweden is considered to have one of the world's highest animal welfare standards in agriculture. Despite this, there are shortcomings in animal husbandry. One example is overcrowding, which is a way to increase stock size without making costly investments in the buildings. It can be carried out systematically to increase profitability or due to, for example uneven calving during the year. The European Commission criticizes the fact that stocking density is not controlled under Swedish welfare inspections.

The purpose of this study is to examine the accessibility with public transportation in the case of the Umeå Region in northern Sweden. This is done by GIS network analysis where both access to transit stops, as well as access by public transport from stops to destinations is examined. An accessibility index is created from transit frequency and travel times to destinations. The results is compared with population register data to calculate what shares of the population has which levels of accessibility with public transportation. In the Umeå Region there are different levels of accessibility by public transport for different parts of the region, where transit stops in the most densely populated areas has the highest levels of accessibility, as well as stations along the railroads.

Uppsalahem AB is a municipally owned real estate concern that owns and administrates housing for nearly 30 000 people. The company puts a lot of effort into reducing the energy use of their housing stock. This project is a master?s thesis in the energy systems programme at Uppsala University, carried out in collaboration with Uppsalahem. The aim of this thesis is to provide energy saving measures for fourteen student housing buildings in Uppsala, Sweden.