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412 Uppsatser om Stem cell - Sida 9 av 28

Robotiserad produktionsanpassad magnetmontering för vågkraftverk

This thesis work includes studies and simulation how magnetization of the translator in a linear generator for wave power can be automated. The translator is the moving component in the generator that is "dressed" with permanent magnets. The translator is magnetized with rectangle-shaped permanent magnets that are today's strongest permanent magnet type of neodymium-iron-boron (NdFeB).Eight equivalent metal sheets are mounted around the translator. The plates have milled tracks where 106 permanent magnets per sheet are mounted. Today the assembling of the magnets is done by hand, which is a very tedious and time-consuming work.  This project presents investigations about the automation of the translator magnetization theoretically and simulation results are preformed in ABB's robot simulation software RobotStudio. Even robot-held tool was designed that enables the robot to be able to magnetize the translator in a simple manner.  The investment cost is roughly 1.5 million SEK. With an economic life-time of five years, the investment costs are estimated to 24000 SEK / month.  According to the calculations, this project is very motivated to implement, as it provides savings up to 17 000 SEK per translator which is 10.2 million SEK assuming that the robot cell is operating at full speed the whole year.According to this thesis work the result is a 4x9 meter cell with two industrial robots of the type ABB IRB6650S.The cycle time to magnetize one translator was calculated to about 10 hours.This prototype of project can possibly be implemented in a full-scale production line and performed according to the calculations and simulations presented in the report. Further work is suggested to improve the tool.Lyssna .

Resultat från tre klonförsök med fågelbär, Prunus avium L, i södra Sverige :

This study was based on measurements of growth and shape of 50 clones of wild cherry, Prunus avium L, in south Sweden and aimed at finding out wether or not any of these clones are useful for commercial propagation. Initially, a short assembly of documented knowledge concerning wild cherry as a timber producing tree species was put together. The study of the 50 clones includes information gathered during the fall of 2006 from four trials located in the counties of Blekinge, Småland and Västergöland. The oldest trial, founded in Tranemåla, Blekinge, in 1992, was focused on offspring and aimed at discerning differences between provenances and at developing an adapted plant material. The other experiments were both clone trials and founded in 2002. These are based on 50 individuals selected from the offspring trial in Tranemåla.

Site preparation, planting position and planting stock effects on long-term survival, growth and stem form properties of Pinus contorta on southern Iceland

In order to evaluate different afforestation methods for exposed heath lands a field experiment was established in Mosfell on southern Iceland in 1989. The trial comprised six different site preparation methods (control, herbicide application, tree shelters, patch scarification, TTS trenching and mounding). In total 960 container seedlings (1+0) and 960 Nisula roll transplants (2+1) of lodgepole pine were planted. Various planting positions (furrow, hinge, no site preparation (control) and on top of mounds) were tested within the site preparation treatments. This study involves renewed measurements and analyses of the trial.After 19 years the overall survival was 51,7 %.

Recreation in the urban countryside

Barley is one of the most important cereals cultivated in the Nordic countries. Climate change brings warmer and moisture climate which favors fungal diseases. In the cropland barley can be seriously infested with hard fungus attack. Since it is important that the yield bears a high quality it is of great importance to find varieties more resistant to attacks.Pathogenesis-related (PR) proteins are stress proteins induced in the plant in response to infection and abiotic stress (van Loon, 1997). PRs are shown to have antimicrobial activity differing between bacteria, fungi and oomycetes (Tandrup Poulsen, 2001).

Karaktärisering av hund TK1 för användning som tumörmarkör :

Thymidine kinase 1 (TK1) is an intracellular enzyme involved in ?the salvage pathway? where the uncomplete parts of DNA are transformed into DNA precursors. The expression of TK1 is cell cykle specific, with the highest level during S-phase when DNA-synthesis is most active. One kind of TK1 is present in serum and an increase in TK1 activity in serum is due to either the level of DNA synthesis in the body or the number of cells dying in a state of replication. This can be used and is used as a marker for prognosis and evaluation of treatment in human patients with leukemia and lymphoma.

Identifiering av röjningsbestånd med hjälp av flygburen laserskanning

Bergvik Skog is one of the leading forest companies in Sweden who use airborne laser scanning for forestry information. They utilize laser data retrieved by the Swedish National Land Survey to describe the forest holdings and facilitate planning for thinning and final felling operations. However, the possibility to identify stands with clearing needs by using laser scanning data has not been tested in a large scale. The data used in the current study are field data from The Swedish National Forest Inventory in combination with laser data from the Swedish National Land Survey acquired in 2009. The collected data is used to find one or several laser variables that best describe the relationship of the field measured samples with clearing needs.

Höggallring i praktiskt skogsbruk : beskrivning av en gallringsmodell för granskog som tillämpas på Trolleholms Gods

When Norway spruce is planted with large initial spacing and grows on highly productive sites in southern Sweden, a high proportion of the stems gets broad annual rings. The thinning programme carried out at the estate of Trolleholm aims to extract stems with too broad ring width. The 3-4 first thinnings are carried out as thinning from above, where only the thickest trees are removed. The internal distance may not fall below 5-7 meters depending on the number of thinning (short distance in young stands). The aim of this study was to examine the thinning model that is carried out at the estate of Trolleholm. A volume table is calculated to describe the model, and data is collected on temporary plots.

Fertilization in Eucalyptus urophylla plantations in Guangxi, southern China

StoraEnso decided in year 2002 to build a pulp mill in the province of Guangxi, southernChina, and also establish eucalyptus plantations to provide it with raw material. By 2010StoraEnso controls about 90 000 of planned 120 000 ha, out of 75 000 ha is already plantedwith Eucalyptus.By using better genetic material, improve the tending, selecting the sites more careful and byusing a proper fertilization regime StoraEnso hopes to increase the mean annual incrementfrom today?s 25 m3/ha, on bark, to 35 m3/ha. This study is one part in this work to increase themean annual increment in the plantation.This master thesis is the forth in a series, that has followed up a fertilization trial that startedin spring 2006 when the trial was laid out and treatments decided. The aim with the trial is toexamine the production potential of Eucalyptus urophylla in Guangxi, southern China.

Early immune responses to an adjuvant (AbISCO-100) tested in porcine peripheral blood mononuclear cell

Immune stimulating complex (iscom) matrix is a formulation that is used as anadjuvant within research. The capability of the iscom matrix to elicit an immuneresponse when not present together with an antigen has not been extensivelyinvestigated. One way to evaluate the status of the immune system is to measure theamount of cytokines that usually are produced by various cell types during an immuneresponse. The aim of the present study was to evaluate the early immune responses inporcine peripheral blood mononuclear cells (PBMC) after stimulation in vitro with theiscom matrix, AbISCO®-100. The immune response was evaluated by measuring themRNA expression for various cytokines, a chemokine receptor (CXCR4) andregulator of G-protein signaling (RGS16) in porcine PBMC after stimulation withAbISCO®-100 or other inducers like a lipopolysaccharide (LPS) and a CpGoligodeoxynucleotide (ODN 2216) used as controls.

Improvement of positive strand assay used in detecting positive and negative RNA of hepatitis E virus

Background: Hepatitis E (HEV) is a small, non-enveloped virus that belongs to the viral genus Hepevirus. HEV is a positive sense single-stranded RNA virus and there is insufficient information regarding its replication. This is mainly because the virus has low capacity to grow in normally used cell cultures. Many specific strand assay detection studies have been done in order to understand more about HEV replication. Unfortunately, these assays have the disadvantage of giving false positive results.Aim: The aim of this project was to improve the positive strand assay to increase specificity and eliminate false positivity which is due to high sensitivity of the polymerase chain reaction (PCR).

Identifiering av gallringsbehov med hjälp av flygburen laserskanning :

Thinning is one of the most important silvicultural activities in middle aged forests, partly to minimize damages and partly because it leads to earlier harvesting revenues and increases the value of the remaining trees. There are many different indices used to describe stand density and thereby the need of thinning in forests today. Studies have shown that forest variables can be estimated with high accuracy using airborne laser scanning and it is likely that the method could also be used to estimate forest density indices. In this study, the possibility of using the forest density index ?H² to determine and map priorities for thinning operations for a forest area was examined.

The screening for novel proteasome inhibitors as a treatment of cancer using IncuCyte FLR and fluorometric microculture cytotoxicity assay.

The problem of finding targeted medicine is a central problem in chemotherapy. From this point of view the ubiquitin-proteasome system is a highly promising object in the pharmaceutical approach. Proteasome plays a critical role in cellular protein degradation, cell cycle and apoptosis regulation.Proteasome inhibitors are substances blocking the actions of proteasome. Cancer cells are more sensitive to inhibition of the ubiquitin-proteasome system than normal cells. Therefore proteasome inhibitors have the potential to be successfully used in the cancer treatment.The study aimed to test various substances to identify possible proteasome inhibitors with the IncuCyteTM FLR image system and fluorometric microculture cytotoxicity assay.

Strålbehandling på hund och katt :

Jönköping Small Animal Hospital is today the only clinic in Sweden to offer radiation therapy as a treatment of tumours. The body contains of billions of cells that all have to obey the regulations that are established. If a cell is exposed to a harmful substance, for example a chemical, it can be transformed into a tumourcell. Normally the body has a good defence but the tumourcell can survive and start to divide unrestrained. A tumour is starting to develop.

Mastcellens roll vid atopisk dermatit hos hund

SAMMANFATTNINGDenna litteraturstudie har gjorts med syfte att utöka kunskapen om atopisk dermatit hos hund med fokus på mastcellens roll i immunopatogenesen. Atopisk dermatit är en relativt vanlig sjukdom som kan drabba alla hundar oavsett ras; den är oftast livslång och kräver visst arbete för att diagnosticera och behandla med gott resultat. Förutom att det är ett problem hos hundar, finns även ett nära samband med atopiska sjukdomar hos människa, och hundar fungerar som en bra modell för forskning på humansidan.Trots omfattande forskning, vet man fortfarande inte varför sjukdomen uppkommer. Många teorier finns kring den immunologiska bakgrunden, men stora delar är fortfarande okända. Att mastcellen spelar en nyckelroll är dock allmänt vedertaget.

Immunohistochemical detection of thymidine kinase 1 in canine mammary tumors and lymphomas

The dog has often served as a model animal for humans in scientific studies. This is due to the fact that dogs are susceptible to a wide range of diseases which also affect humans. One example is cancer, a condition that affects dogs as well as owners. Neoplastic diseases account for 18-23 % of all deaths in dogs (Bonnet et al., 2005 and Jagielski et al., 2002). Mammary tumor, or tumor of the breast, is the most common tumor form in intact dogs and women (Im et al., 2013). Mammary tumors originate in the udder, and are classified according to their histological characteristics.

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