The aim of this study was to compare the effect between the drugs rituximab and infliximab in rheumatoid arthritis (RA). RA is an autoimmune disease that affects the peripheral joints and is associated with exacerbations. Various immune reactions in the body cause inflammation of the joints which further results in cartilage and bone damage. The diagnosis is made by the classification system "The 2010 American College of Rheumatology (ACR) / European league against rheumatism (EULAR) classification criteria for rheumatoid arthritis", which is an update of the older system called "The 1987 American College of Rheumatology classification criteria for RA". Approximately 0.5-1% of the population is developing the disease, but it varies slightly between different parts of the world.

A common perception is that fungicide treatments increases yield, but that the nitrogen of the particular grain is diluted so that the overall removal of grain nitrogen from the field remains unchanged. The aim of this paper is to demonstrate that a healthy crop reduces the risk of nutrient loss from agricultural land. The results from genotype and plant protection trials often show constant nitrogen content in the grain, although the yield has been increased. Results from such experiments are therefore processed in order to confirm this and show that it is no statistically significant difference between the protein content (and also nitrogen content) in crops which have undergone fungicide treatment compared to crops which remained untreated. The trials processed have been carried out in the southernmost part of Sweden and are distinguished to concern winter wheat production.The explanation to the results is that a healthy crop is able to maintain the biological functions of the plant in a more efficient way than a crop damaged by a fungal infection.

Syftet med studien är att få ökad insikt i hur sånglärare med utgångspunkt i kursplanens mål om genrebreddning hanterar genreområdet jazzsång i sångundervisningen på gymnasieskolans estetiska program. Genom att intervjua fyra sångpedagoger verksamma på gymnasiets estetiska program har jag tagit reda på vad som enligt dem kan betecknas som ett genreenligt sound eller genrespecifika egenskaper speciellt viktiga för jazzsång, hur dessa kunskaper kan förmedlas till eleverna samt hur sångpedagoger använder sig av jazzsångens genrespecifika element i sångundervisningen. Studien har som sin teoretiska utgångspunkt ett sociokulturellt perspektiv med fokus på hur pedagoger använder olika redskap för att kommunicera och lära ut.För att få svar på mina frågor har använt mig av en halvstrukturerad intervjuform. Informanterna är alla yrkesaktiva sångpedagoger, två med en mer klassisk inriktning och två med afroinfriktning. Resultatet visar att jazz som genreområde är svårt för pedagogerna att definiera och ingår i undervisningen i den mån pedagogen styr det därhän.

The purpose of this study was to describe the possibility of implementing a lacto-ovo-vegetarian and organic diet in Eskilstuna municipality?s public preschool. Furthermore the purpose was to identify and describe the most important components involved in the implementation and their influence in the process.  The methods used were a survey based on a literature study. This study includes general information about meat production and consumption and also the use of pesticides in farming. It also brings up the environmental and health effects caused by the previously mentioned areas.

Distributed, renewable generation-units and more efficient use of electric power,demands a developed electric grid. This grid is often referred to as the ?Smart Grid?.This future electric system rise expectations among actors in the existing electricmarket. International organizations share visions of opportunities for electricityconsumers and new actors, ready to enter the market. At the same time, electricutility companies may question the need for some of these upcoming changes, as theyare sometimes expected to lead the development.This paper therefore seeks to investigate the business opportunities related to SmartGrids.

This thesis aims to increase understanding and knowledge of issues affecting the redevelopment of older office buildings to housing. The rising demand for housing in recent years has resulted in a need and an increase in cost housing projects. The need has led property owners wanting to build old office buildings to apartments. The case study is carried out in Lycksele town and in close contact with consultancy TM (Technician Mercantile) ? consulting, which has operations in the area.

Studier har visat att höga bullernivåer kan vara skadliga för såväl röst, hörsel och språkliginlärning som andra kognitiva förmågor. Höga ljudnivåer kan bidra till ett hyperfunktionelltröstbeteende som kan ge kroniska besvär. Barns röstorgan kan vara särskilt sårbara då de ännuinte är fullt utvecklade. På många förskolor är bullernivån hög och ogynnsam för både barn ochpersonal och därmed utgör de båda en riskgrupp för att utveckla röstbesvär och hörselskador.Föreliggande studie består av ljudnivåmätningar av två förskolors lokaler samtfokusgruppsintervjuer av 16 femåriga barn. Syftet var att kartlägga hur barnen upplever bulleroch kommunikation på förskola samt relatera det till uppmätta ljudnivåer.

Laminitis has crippled horses through times and many cures have been used to treat it. Since the mechanism of the disease is yet not fully understood, treatments are only ways to alleviate the pain and at best, slow down the pathological process enough to make time for improvement. This paper is a retrospective study of 71 horses treated by a protocol at Hästsjukhuset Strömsholm. The protocol implies three visits at zero, five and fifteen weeks. At each the horse is evaluated and treated by a veterinarian.

The objective of this thesis is to map the resources and methods used at the department OPPC, at AstraZeneca, and derived from that give suggestions on possible solutions that will increase their productivity.Mapping of the product flow, as well as gathering of process data, has mainly been done using observations, but consultation with the process technicians has also played a great role. Further have theoretical methods been used, based on literature studies, within the areas of Lean production and statistics.The work has incrementally gone forward since the steps taken has been restricted by the irregularity of production which led to the need of creating a fictive production flow. This has affected the lead-time calculations in the way that they are meant to give an indication, rather than an absolute truth, on how different methods described shall be used.The current state analysis showed multiple areas of improvement when defining capacity as value adding time in relation to total throughput time. Using the "standard scenario" as a basis showed that the actual production flow only constituted 50% of the total project time. Further it showed that the workflow contained more non-value adding activities than value adding activities, which is a result of how the work is distributed within the department as well as in the different projects.

Introduktion: Skolios som drabbar barn och ungdomar ger en krökning av ryggraden i sidled. Upprepade undersökningar med joniserad strålning av främst flickor i puberteten innebär risk för bröstcancer. Genom att på olika sätt optimera undersöknings metoderna och använda skydd till patienter kan biverkningarna minskas. Syfte: Syftet med studien var att genom en systematisk litteraturöversikt sammanställa vilka metoder och röntgenparametrar som kan användas för dosreducering i samband med radiologisk skoliosundersökning av barn och ungdomar. Metod: Studien utfördes som en allmän litteraturöversikt.

Background: Mass customization has been identified as a competitive business strategy by both companies and academics because of its ability to incorporate the voice of the customer into companies? products and services. Although mass customization may sound appealing, the strategic concept is still developing and firms adopting this business strategy face several challenges. Production concerns are of high relevance since mass customization implies a high level of customer involvement in the product design. Since the areas are closely linked it is reasonable to ask how a mass customization strategy affects production concerns.

There is little knowledge about abuse of anabolic androgenic steroids (AAS) in Sweden. Thispaper aims to explore, from a discourse psychological angle, how persons with experience ofanabolic androgenic steroids (AAS) construct there identities.The theory and method used as a frame for the paper is discursive psychology, depending on thefocus in the paper of human beings use of language in the construction of identities. Forcollection of data interviews were made. The six respondents al had experience of use of AAS.The interviews illustrated how users of AAS speak about AAS, and create there identity, inrelation to AAS. In the interpretation of data we used two different tools, used by discursivepsychologists, interpretative repertoires and subject positions.

Many jobs in rural areas have historically been linked to the agricultural sector. The restructuring that has been implemented in agriculture has resulted in a significant reduction in the number of jobs in rural areas. A consequence of this is that many people have moved to cities to earn a living. To maintain a living countryside in Sweden, it is therefore essential to create alternative livehoods in rural areas. An industry that can have a major impact in the future is rural tourism.

Det här arbetet syftar till att genom design av en telefonapplikation undersöka hur ljud kan förstärkas av den omgivande miljön. Arbetet visar på hur miljöförstärkt ljud skiljer sig från ljudförstärkt miljö samt vilka begränsningar det innebär att använda en vanlig smartphone som plattform. Ett långsiktigt mål är att genom en produkt som låter oetablerade ljudproducenter distribuera sina alster i den offentliga miljön främja fri kultur och kreativitet.Arbetet har följt principen för RtD (research through design), där designprocessen utgör det fall som studeras och dokumentationen av den utgör den bas av data som analyseras och leder till slutsatser kring ämnet.Designprocessen i detta arbete innebär en mindre omfattande användarstudie i enkätform för att identifiera målgrupp, krav och mål. Följd av en andra studie där en prototyp framtagen med grund i resultaten från användarstudien utvärderas av deltagare genom observation, intervju och reaktionskort. De största utmaningarna för designen grundar sig i att ta fram en applikation som inte stör upplevelsen, men samtidigt kan instruera användaren i hur man använder applikationen. Utifrån arbetet dras slutsatsen att användarinstruktioner, såväl visuella som auditiva, löper större risk att störa upplevelsen i miljöförstärkt ljud än i ljudförstärkt miljö. Vidare konstateras att den största bristen i en lösning som bygger på standardutrustning i jämförelse med en lösning som nyttjar dedikerad utrustning utgörs av begränsningar när det kommer till att ange riktning med hjälp av ljudets rumslighet..

The climate changes that are occuring in the world have resulted in that the EU callingfor a 20 % reduction in energy consumption to the year 2020, to reach that goal theEU want the public sector to go forth as a good example. Västfastigheter owns andmanage the hospital buildings in the Västra Götaland region. To be able to reducetheir energy usage Västfastigheter has hired several consulting firms to chart out theenergy consumption on each hospital building. The biggest energy savings potentialhave been calculated and what the cost will be to perform each action. The energyaudit have been completed and stand as the decision basis for Västfastigheter?s choiceon which action packages that should be implemented.