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68 Uppsatser om Somatic hypermutation - Sida 1 av 5

Immunoglobulin VH gen analys in human B-cell

Malt lymphoma is a malignant disease that can arise in a variety of extra nodal sites. Previous studies indicate that tumour arise from more mature B-cells.Our purpose was to examine the presence of clonality and Somatic hypermutation of immunoglobulin (IgV?) of MALT lymphomas.Paraffin-embedded tumour samples from13 MALT lymphoma were subjected to rearrangement analysis, by using PCR, heteroduplex gels and sequence analysis.Successful amplification was seen in 10/13 cases and sequences of IgV? genes were obtained in 6/13, all of them were mutated. The percentage of mutation compared to germline sequences was 1,1% to 8,6% monoclonal rearrangemang. It was demonstrated that 5 of 7 clones were derived from the V?3 family, 2 from V?1 and 1 from the V? 4 family..

Sjuksköterskors erfarenheter av patienter med psykisk sjukdom inom somatisk vård

Background: Studies showed differences in attitudes towards patients with mental illness in nurses who worked in somatic care compared to nurses who worked in psychiatric care. The nurses in somatic care stated more negative attitudes to mental illness in relation to the nurses in psychiatric care. Studies also showed that work experience affected attitudes towards mental illness. Nurses who often came in contact with people with mental illness had less negative attitudes and prejudices against mental illness. Aim: The aim was to examine the experiences from nurses in somatic care, caring for patients who also have a psychiatric diagnosis.

Sjuksköterskors erfarenheter av att uppmärksamma, bedöma och hantera somatiska symtom och problem i det psykiatriska omvårdnadsarbetet

Background:Patients with mental disabilities are more prone to somatic illnesses than the general public. Unhealthier lifestyles and side effects of medication might be causes of conditions that lead to diabetes, cardiovascular diseases and premature death. According to the Social Board patients with mental disabilities receive poorer treatment than patients with only somatic diagnosis.Aim:The aim of the study was to describe nurses' experiences to identify, assess and manage somatic symptoms and problems within the psychiatric care.Method:The study is based on interviews with 12 nurses working in psychiatric outpatient and inpatient care. A qualitative content analysis was chosen.Result:The nurses performed nursing through talking, blood sampling and measuring for example blood pressure. They followed up side effects of medication.

The effect of arginine on root system development in Norway spruce (Picea abies L. Karst) somatic embryos

The demands for higher production yields and better quality materials from the forests are increasing globally. Tree breeding programs are directed to meet the future demands on forests. In order to capture the full benefits from the breeding programs, clonal propagation is necessary. For most conifer species, somatic embryogenesis (SE) is the only available option for large scale clonal propagation of Elite clonal material. For Norway spruce (Picea abies L.

Underhållsarbete på krafttransformator : En studie på genomförande av underhållsarbete i transformatoranläggningen med optimeringsförslag.

This report is the result of a project in the course Independent Projekt in Molecular Biotechnology at Uppsala University during the spring of 2014. The foremost purpose of the course is to give students the opportunity to carry through exstensive work in a project environment. This project was formed based on a comission from the biotechnology company SweTree Technologies, and the goal has been to compose a summary of the different techniques and methods that exist in the field of mass propagation of trees through the method of somatic embryogenesis.The project group has obtained information about the area mainly throgh reading patents, trying to find key components and bottlenecks in other companies? somatic embryogenesis technologies. This paper is divided into different sections, containing the patents of the automation of different steps in the process.

Automatiserade metoder för somatisk embryogenes ger effektivare trädproduktion : En patentundersökning av befintliga metoder för processens flaskhalsar

This report is the result of a project in the course Independent Projekt in Molecular Biotechnology at Uppsala University during the spring of 2014. The foremost purpose of the course is to give students the opportunity to carry through exstensive work in a project environment. This project was formed based on a comission from the biotechnology company SweTree Technologies, and the goal has been to compose a summary of the different techniques and methods that exist in the field of mass propagation of trees through the method of somatic embryogenesis.The project group has obtained information about the area mainly throgh reading patents, trying to find key components and bottlenecks in other companies? somatic embryogenesis technologies. This paper is divided into different sections, containing the patents of the automation of different steps in the process.

Analys av juverhälsodata från kärnbesättningen Viken :

Nötcenter Viken is a Swedish nucleus herd for dairy cattle. The goal for the farm is to select suitable mothers for the next top generation of bulls. Today the selection for udder health is based on a pedigree index and phenotype data. The pedigree index is based on the cow?s father and grandfathers breeding values.

Ett nytt multiplext PCR-protokoll för identifiering och detektion av Shigella och enteroinvasiv E. coli (EIEC) från livsmedel

This report is the result of a project in the course Independent Projekt in Molecular Biotechnology at Uppsala University during the spring of 2014. The foremost purpose of the course is to give students the opportunity to carry through exstensive work in a project environment. This project was formed based on a comission from the biotechnology company SweTree Technologies, and the goal has been to compose a summary of the different techniques and methods that exist in the field of mass propagation of trees through the method of somatic embryogenesis.The project group has obtained information about the area mainly throgh reading patents, trying to find key components and bottlenecks in other companies? somatic embryogenesis technologies. This paper is divided into different sections, containing the patents of the automation of different steps in the process.

Riskfaktorer för Staphylococcus aureus i mjölk och på has hos mjölkkor :

Mastitis is the most common disease of dairy cows. Mastitis can be painful for the dairy cow and causes economical losses for the farmer. These losses are due to decreased milk production, more working hours for the farmer, treatment costs and possible costs due to culling of the cow. The udder inflammation, mastitis, is often caused by bacteria infection. One of the most common bacteria found to cause mastitis in Sweden is Staphylococcus aureus (S.

Förändras mjölkens proteinsammansättning i separata juverdelar i samband med höga celltal (SCC)? :

Today the milk production per cow is increasing but the milk delivered by the Swedish farmer contains less amounts of fat and protein than earlier. The contents have decreased since 1993. In average the milk contain 4,2 percent fat and 3,4 percent protein. Earlier the fat content in milk was important. Nowadays the dairy?s attention has turned to the milk?s valuable proteins, principally the caseins, which have a considerable nutritional value and are important for several dairy products like cheese and yoghurt.

Hur en övergång till ett automatiskt mjölkningssystem påverkar juverhälsan :

Automatic milking systems (AMS) have been in commercial use since 1992 and have since 1998 increased a lot. The objective of this study has been to examine the development of udder health on farms converting to AMS. The study also included a comparison of how udder health developed depending on how farms handled cows with mastitis. This was because farms choose to either milk cows with mastitis in a separate barn or in the milking robot. Other studies on udder health on commercial farms have shown that somatic cell count increases both among individual cows and in the bulk milk when converting to an AMS. No differences between before and after converting to AMS in the proportion of cows treated for mastitis can be found in the literature.

Use of oxytocin to improve diagnosis of subclinical mastitis caused by Staphylococcus aureus

Mastitis, inflammation in the udder tissue, caused by S. aureus is a big problem in dairy cattle production. It causes suffering for the cow and curing or replacing the infected cow is costly for the farmer. It is known that beef cattle also suffer from mastitis caused by S. aureus.

Variationer i kostnader för specialiserad sjukvård - En analys av demografi, socioekonomi och hälsans inverkan på kostnaderna för specialistvård i Västra Götalandsregionen

Abstract. Aim: The aim of this study is to determine certain health, demographic and socioeconomic factors that affect the costs for specialized health care between the municipalities within the Västra Götaland region. Method: The method is explorative and analytical. The costs for specialized health care was divided into three different subgroups; independent somatic specialized health care, specialized health care provided by private practices or outside the region and psychiatric specialized health care. The data was age-standardized.

Strålskydd :

This paper describes how radiation affects the body, the somatic and genetic effect that can occure in exposure of ionizing radiation and how to protect yourself against it. How radiation affects the cells and why you can get cancer if you get exposed of a large amount of radiation is mentioned. Research after a threshold is mentioned and what Sweden does today to improve the radiation protection by laws and regulations. Explaining the atom, what radiation is and how the ionizing radation interacts with the atom. How backscatter affect the picture and the workers and how to protect yourself from backscatter is mentioned. Radiation doses, dosimetry and rules for those who practise radiation is shortly described..

The Golden Rule and Bioethics. A Reflection upon the Foundation of Ethics

The object of this thesis is the foundation of ethics. The question is whether there exists a universal core to ethics consisting of a fundamental ethical principle across cultures. This principle could for example be the so-called Golden Rule, which goes as follows: ?You should do to others what you want them to do to you?. The Golden Rule is to be found in many of the world?s religions and is also reflected in secular society.

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