Alternative splicing is a process that partly rejects the common definition of a gene ? that one gene codes for one specific protein. By variable combination of coding regions (exons) and exclusion of non-coding regions (introns), formation of several different mRNA-transcripts, and consequently several different proteins, can derive from the same gene. Alternative splicing is an important condition for the development of complex life forms, but it is also a highly sensitive process and inaccurate splicing is the cause of approximately 15 % of mutations that cause genetic diseases. This article presents four genes, BRCA1, BRCA2, ER? and ER?, and inaccurate splicing of these genes increases the risk of developing cancer, particularly breast cancer and ovarian cancer.

The focus of this research is to investigate how the client's emotions can affect the social worker and how the social worker manages these feelings in order to make the right decisions. We have used a qualitative approach in our investigation. We have interviewed six social workers at social welfare bureaux in southern Sweden. Our theories are ?Nai?ve Theory? and ?Affect Theory?.

Uppsatsens syfte är att förklara skillnaden i varför företag noterade på Stockholmsbörsen lämnar olika upplysningar om risker och osäkerhetsfaktorer. Studien baseras på företag noterade på Stockholmsbörsen OMX, Large-, Mid-, och Small Cap. Sammanlagt granskas 200 noterade bolag utifrån dess årsredovisningar. Undersökningen delas in i fyra olika riskkategorier; finansiell risk, affärsrisk, operationell risk samt strategisk risk. Varje kategori, med sina beroende variabler, analyseras var för sig.

This paper aims to explore the relationship between financial risk and ESG scores in order to assist investors in making investment decisions. We investigate the hypothesis that there is a relationship between the ESG score of a company, and the financial risk in terms of volatility in the relevant company?s share price. The paper is grounded in sustainability reporting and financial risk. With the world facing significant changes and natural disasters, there is an urgent need for action to mitigate environmental impacts to avoid devastating consequences.

The purpose of this study was to explore the connection between substance abuse and completed/attempted suicide. Central questions were who the substance abusers who commit suicidal actions were. The study also tries to find out which factors that contributes to this behaviour and why it is so common amongst substance abusers. All from the point of view of three scientist and three persons working with treatment of addicts who were interviewed. The results of these interviews were analysed on an individual level with a psychological theory.

Background:Investments in different forms have always been popular to every human being. For the most common investments, such as stocks and bonds, there are loads of information to gather for the investor. Historical data like risk, return, dividends and fundamental data like annual reports are often very easy to find, regarding these kinds of investments. The background of this thesis is the lack of market information in residential real estate investments. A problem with this investment is that there is lack of information regarding risk adjusted return for real estates, which this thesis intends to present.Objective:The objective with this thesis is to study which alternative, directly-owned residential estates or stocks, who generates the highest risk adjusted return.

The purpose of this paper was to investigate how teachers work to lead and motivate high-performing students, and how these students were defined. The method used was qualitative, more specifically an interview, which was then analyzed with a thematic analysis. Six teachers participated in the survey, and what emerged was that high-performing students were often ambitious, structured and social students. High performing students were also characterized by the fact that they needed challenges, attention and positive feedback on their performances, otherwise they ran a risk of not performing. Structure was also important for the teachers themselves, that they had a goal when teaching and a way of achieving that goal.

Risk management has become a key ingredient for businesses all over the world. High Reliability Organizations (HRO) has distinguished themselves as experts in this area. By continuously focusing on improving their ability to manage risks they?ve been able to successfully avoid catastrophes in environments where normal accidents can be expected due to complexity and risk factors.The aim of the thesis is to improve the risk management at Apotekens Service by applying theories from HRO and safety culture. In July 2009, following the re-regulation of the Swedish pharmacy market, Apotekens Service AB was appointed national pharmacy infrastructure supplier for the Swedish health care system.

The purpose of this study was to examine how social work professionals view their professional role and how they think about the concept of social work. I also wanted to investigate what they believe characterize a professional social work. For the purposes of this study, I chose a qualitative approach in which I interviewed five people linked to the social work. The theories which I have assumed in the analysis of the results are power theory, organization theory and professional theory. The results of this study show that the respondents believe that a professional social work is performed by someone who has training and experience in the field.

The purpose of this study was to examine the school counsellors and social service workers experience of how the child psychiatry manage their authority in the collaboration concerning children with mental health problems. The study was conducted using qualitative interviews with school counsellors, social service workers and one former employee of the Swedish child psychiatric care. Our results are divided into two themes: Collaboration and distribution of responsibility and Children who fall between the cracks. Examples of groups of children who according to our study are at risk of falling between the cracks are those who apart from mental issues have substance abuse issues or social issues, those whose parents are in a child custody dispute, children who are acting out and children with self-harm issues. The study also reveals that it's easier for children whose parents are active and knowledgeable to get help from the child psychiatric care and that it's a requirement for both parents and children to be highly motivated.There are established social hierarchs between agencies who partake in collaboration regarding children with mental illness.

Social sustainability is often regarded as a solution to social problems in general. In this study, on the contrary, social sustainability is conceived as a socially constructed concept and the result of a certain way of looking at the world, the human being and the ideal society. The study centers around Kinda municipality in the southern region of Östergötland and a few of its elder inhabitants. What meaning and substance social sustainability is contained with as well as the effects that are produced by these conceptualizations is explored and analyzed. Also, the study examines the encounter between political policy?s and judgments on the one hand and the experiences and preferences held by the municipality?s elder inhabitants on the other..

Risk- och beredskapsfrågor är idag mycket aktuella inom olika verksamheter. Studien undersökte hur barnomsorgspersonal i Örebro betraktade risk och beredskap i arbetet samt hur känslan av sammanhang (KASAM) samt arbetsrelaterade faktorer som krav, kontroll och stöd påverkade dessa upplevelser. Studien baserades på enkäter byggda på frågeformulären QPS-Nordic 34+, 13 frågors KASAM samt egna frågor. 53 personer deltog. Resultatet visade att den upplevda beredskapen var god i förhållande till den upplevda risken.

Risk- och beredskapsfrågor är idag mycket aktuella inom olika verksamheter. Studien undersökte hur barnomsorgspersonal i Örebro betraktade risk och beredskap i arbetet samt hur känslan av sammanhang (KASAM) samt arbetsrelaterade faktorer som krav, kontroll och stöd påverkade dessa upplevelser. Studien baserades på enkäter byggda på frågeformulären QPS-Nordic 34+, 13 frågors KASAM samt egna frågor. 53 personer deltog. Resultatet visade att den upplevda beredskapen var god i förhållande till den upplevda risken.

In order to facilitate trade between EU members, the European Committee has created regulations that will govern supervision of organic products. Every regulatory agency shall, according to the European Committees regulations, carry out a risk classification of each organic producer they regulate. This study for The National Food Administration compares regulation of Swedish organic products with other countries, and aims to produce a simplified model based on risk that can be the beginning of the risk classification model that Sweden in the current situation don?t have. The thesis is based on three questions: 1) What criteria should we use for assigning organic food producers? 2) How do selected European countries and frontrunners rate organic producers and what can Sweden learn from them? 3) How might a national classification model of organic production look in order to ensure an equivalent level of regulation and prevent competition among private inspection bodies? A review of information gathered from the different countries gave differing results.

To complete an overweight treatment program is associated with better weight loss. Previous studies have in principle focused on drop-out from the entire program, not individual parts of a program. Factors previously shown to influence the patients´ weight loss results are: frequency of individual meetings with a professional, the lack of social support from family or friends, the lack of motivation and in a few studies vacations. In several studies the drop-out patients have stated that their reasons for drop-out were dissatisfaction with the staff and the program design. Drop-out has also been shown to be connected with difficulties in adherence to the diet.