Nitrogen deposition leads to environmental damage in areas where the nitrogen deposition is high. Southwest Sweden receives an annual nitrogen deposition of up to 20 kg N/ha. Nitrogen that is not assimilated by the vegetation is accumulated in the soil, which may lead to nitrogen saturation and an elevated risk of nitrogen leaching. Nitrogen leaching from forest areas in southern Sweden has proven to be higher than from agricultural areas, which have been thought to be the main contributors to elevated nitrogen levels in rivers and lakes. The amount of nitrogen that leaches depends on the fraction of the total nitrogen in the soil that consists of nitrate, since nitrate is easily transported through the soil.

When performing studies that test the reactions of horses in different situations, important information may be available about the horse?s reactivity level. With information from these tests, accidents and dangerous situations may be prevented. When the behaviours from tests are compared with race performance it may be possible to evaluate if some behaviours are more desirable at the race track than others. The aim of this study was to see if behavioural responses correlated with physiological parameters (heart rate, cortisol), the trainer?s opinions and actual race performance.

The global climate change affects the Arctic region the most. The decrease in arcticsea ice is one of the reasons why, it accelerates the warm-up of the region.To understand the changes in the Arctic climate, knowledge about what affects thechanges in the sea ice is necessary. One of these processes could be the relationbetween the extent of the sea ice and the concentration of sea salt aerosols in thearea.This work studies how a variation in the arctic sea ice extent affects theconcentration of sea salt aerosols at Barrow, Alaska. To do this aerosoldata, icedataand winddata has been analyzed over the years 1998-2007. The results shows that aseasonally variation in the sea ice extent affects large aerosols (1-10 ?m) whilesmaller aerosols (<1 ?m) doesn?t seem to be affected as much..

This essay is about two areas called Hackås and Myrviken, situated in the middle of Sweden around the lake Storsjön. In Hackås we can see traces after an early agrarian settlement, and in Myrviken we find Jämtlands largest concentration of ironmaking sites from around 400 AD. There are no clear evidence of the agrarian settlement in Myrviken, and only two ironmaking sites in Hackås. These two economies functioned at the same time, but were clearly separated. My purpose is to discuss if it was the farmers of Hackås who made iron in Myrviken, or if it was somebody else..

Feline infectious peritonitis (FIP) is a feline viral disease with high mortality. There is no cure or any effective vaccine available today. Many questions are yet to be answered about this disease and the immune response in affected cats. The aim of the study is to evaluate two different techniques for the study of cytokine profiles in cats vaccinated with a vaccine concept against FIPV. More information about the immune response in these cats could give valuable information to better understand the pathogenesis of the disease and the development of an effective vaccine.

Laminitis is a debilitating disease causing much suffering to horses and ponies all over the world. It is manifested in the hooves as a mechanical failure of the suspensory apparatus between the hoof capsule and the distal phalanx. Due to the weight of the horse the disease may result in a dislocation of third phalanx. Six healthy standardbred trotters were used in this study on whether standardbreds tolerate forced recumbency as well as Shetland ponies. Recumbency was induced pharmacologically but maintained only by lowering the ceiling height of the box to a height of approximately 125 ? 140 % of the horse´s thoracic height.

Apart from recognizing and neutralizing threats, antibodies also have the ability to regulate immune responses against their specific antigen. IgG administered together with erythrocytes is well known to induce >99% suppression. This has been used to prevent haemolytic disease in new-borns since the 1960's, but the mechanism behind it is still not completely understood. The effect on the primary response is well established, but its influence on induction of immunological memory is still heavily debated. In this study adoptive cell transfer of splenocytes to irradiated mice was used to survey the effect IgG has on induction of immunological memory without disturbance from the primary IgG response.

Det saknas idag metoder för att med säkerhet fastställa diagnosen Bornasjuka intra vitum. För att få en så säker diagnos som möjligt krävs fortfarande histopatologiska belägg och påvisande av virus i material från centrala nervsystemet, vilket ej kan tas från levande djur. Trots det finns det en risk att det intracellulära viruset undgår detektion då infekterade celler ej är jämt fördelade i hjärnan. De kliniska symtomen är specifika enbart för infektion i centrala nervsystemet och inte för Bornasjuka. Att förlita sig på antikroppar är osäkert på grund av låg titer som kan göra testen mindre tillförlitliga.

GE Healthcare operates in Uppsala (Sweden) and develops systems, equipments and medium to purify medical substances. Discussions with the local authority concerning planed far-reaching changes and upgrades of the biological process techniques for sewage management, aroused the question about revising the terms of permit for the activity. Therefore it seemed necessary to evaluate a newly installed biological process technique, which is the background of this thesis. The evaluated biological treatment process was built in 2003 and consists of a biological reactor filled with moving bed carriers with a high surface area for biological growth. At the time of the project the biological wastewater treatment plant consisted of a flow equalization facility and two following parallel biological processes; a biological reactor with moving bed carriers and a tower trickling filter.The aim of this thesis was to survey the function of the biological reactor with respect to the reduction of organic matter.

During the past few years a vast amount of research has been done to increase the understanding of the complex ecosystem of the Baltic Sea. Modelling and simulations are important tools to increase knowledge of the system. A suitable model must be simple to use and the parameters and variables needed in the model must be easy to access.In this paper a dynamical mass-balance model, CoastMab, which is validated for smaller coastal areas, has been used to predict concentrations and transports of phosphorus in three large coastal areas - the Gulf of Finland, the Gulf of Gdansk and the Gulf of Riga. CoastMab uses ordinary differential equations to regulate inflow, outflow and internal flows. To reflect seasonal variations in temperature and different types of flows the model has a temporal resolution of a month.

The stability of railway embankment is essential for safe transport. In order to ensure safe transport, water should be allowed to freely drain. Furthermore, as the engine driver has to be able to see signs, and people working on the embankment are supposed to easily see flaws on the rails to ensure safety for the passing trains, plants should not be allowed to grow on the embankment. In Sweden there are 12 000 kilometers of railway tracks and 25?30 % of them are treated for weed control every year.

The quality of bread wheat is a large subject to study. The quality rests on two legs. The first one is the inheritance of specific characters, which can be influenced through plant breeding and type of cultivar. The other one is the environmental influences, such as crop rotation, nutrition, harvest and storage. The latter factors are possibly to affect through cultivation practices, while other factors are not possible to influence on for the grower, such as seasonal changes of weather and the soil content.

In order to facilitate testing of anesthesia machines a patient simulator has been required by Maquet Critical Care AB. A patient simulator has been developed to reduce expensive and time consuming animal experiments and temporary lab arrangements. The patient simulator has been developed and designed to simulate human lungs with regards to anesthetic uptake, production of carbon dioxide and heating and moisturizing exhaled air.The system comprises a container and a test lung to simulate the volume and the dynamic of the human lung. The simulation of uptake of anesthetics has been implemented by pumping a fraction of the gas from the container through a bypass circuit with an active charcoal filter that adsorbs volatile anesthetics. The flow through the bypass circuit is generated by a pump and is controlled by a linear valve.The resulting performance of the patient simulator has fulfilled the requirements.

I denna studie har förekomst av progesteronreceptorer i olika typer av primära juvertumörer undersökts med hjälp av immunohistokemi. Dessutom har tumörceller från carcinomcellinjen CMT-U27 odlats i olika cellodlingsmedium och exponerats för olika testsubstanser som binder till progesteronreceptorn (progesteron och RU486/mifepristone). Cellernas receptoruttryck och progesteroninnehåll utvärderades med hjälp av ELISA och tumörcellernas viabilitet analyserades med Colorimetric Cell Viability Test. Av resultaten framgår att samtliga undersökta primära juvertumörer uttryckte progesteronreceptorer. De odlade cellerna hade högre cellviabilitet när de odlades utan fetalt bovint serum (FBS). Efter exponering med progesteron minskade tumörcellernas uttryck av progesteronreceptorer, vilket hämmades av mifepristone.

During the last few years the presence of high arsenic (As) concentrations in ground water has been of major concern both internationally and in Sweden. Much evidence has been reported about toxic effects caused by arsenic. The carcinogenic effects and the possibility to measure the toxic impacts at low concentrations made the World Health Organisation (WHO) to reduce the guideline value from 50 to 10 ?g l-1 in 1993. In Sweden the corresponding reduction was implemented in 2003. Several surveys in Sweden have shown that high arsenic concentrations may occur in ground water.