FLUTD - Feline Lower Urinary Tract Disease ? is a complex disease and a common sight in the veterinary setting. Although FLUTD excluding urethral obstruction may be discomforting for the cat and its owner due to symptoms such as periuria, stranguria, hematuria, dysuria and pollakiuria, obstruction presents an acute and potentially lethal form of the disease as a result of uremia and disturbances in fluids, electrolytes and acid-base balances. A study of literature has been performed to investigate the causes of FLUTD with urethral obstruction and the actions available to the owner to avert them. Potential causes of obstructive and non-obstructive FLUTD have been found to include infections, uroliths, urethral plugs, neoplasia, anatomic abnormalities, trauma, neurogenic or iatrogenic causes. Most commonly a cause cannot be identified and the terms idiopathic FLUTD or feline idiopathic cystitis are used. As the mortality rate due to urethral obstruction likely is somewhere around 5.8-8.9% and FLUTD including and excluding urethral obstruction constitute great inconveniences, precautionary measures are warranted.

Hydropericardium or pericardial effusion (PE) is the accumulation of fluid in the pericardial sac and is often secondary to pericardial diseases or diseases related to the heart. It is unusual with clinically relevant pericardial diseases in cats but pericardial effusion is the most common one. Since PE causes serious symptoms and may lead to death it is important with a quick diagnosis and treatment. PE can be acute and cause cardiac tamponade, which gives severe clinical signs. Cardiac tamponade needs to be treated immediately or else the cat will die from cardiogenic chock. More common is chronic PE where the fluid accumulates during a longer period of time and the pericardial sac stretches.

 Intensivvårdsjuksköterskan möter i sitt dagliga arbete många patienter som behandlas i respirator. Långvarig respiratorbehandling innebär ofta ökade risker för komplikationer. Med anledningen av detta är det viktigt att minska tiden i respirator med effektiv urträning. Att tränas ur respiratorn är en individuell process och bör därför anpassas efter patientens förmåga. Syftet med examensarbetet var att beskriva intensivvårdssjuksköterskors erfarenheter av tracheostomerade patienters urträning ur respirator.

Influenza is a viral infection that affects global health and economy with its endemic and sometimes pandemic spread. Rapid detection of Influenza viruses enables antiviral use and can bring financial savings. It is also essential for the global surveillance of prevalent Influenza strains. RT-PCR is considered the most specific and sensitive method for detection of Influenza, but Influenza mutates at a high rate and it is therefore crucial that RT-PCR methods are updated regularly.In 2014, Cepheid released their Xpert Flu/RSV XC assay, which can detect Influenza A and B and RSV by multiplex RT-PCR in approximately one hour. The aim of this study was to evaluate this assay at Laboratoriemedicin Västernorrland by using the laboratory?s previous PCR assay for detection of Influenza viruses as reference method.Real-time RT-PCR was used to compare Xpert Flu/RSV XC to the reference method.

Bakgrund: Postoperativa sårinfektioner [PSI] är en allvarlig komplikation och ett hälsoproblem som orsakar lidande för patienten. Såsom vid alla operativa ingrepp förekommer en risk att få PSI i operationssåret/-såren efter Coronary Artery Bypass Graft [CABG], men det finns redan en rad kända riskfaktorer som ökar risken för PSI.Syfte och metod: Syftet med rapporten var att undersöka om kombinationen av ett antal sedan tidigare kända riskfaktorer ökade risken för PSI efter CABG på ett mellansvenskt sjukhus åren 2009-2012. En retrospektiv journalgranskningsstudie med totalt 228 patienter genomfördes.Resultat: Av 228 undersökta hade totalt 50 patienter rapporterat sårinfektion och 73 patienter hade ? 3 riskfaktorer. Bland de som hade ? 3 riskfaktorer rapporterade 32,9% PSI och bland de som hade < 3 riskfaktorer rapporterade 16,8% PSI.

Volvo Human Monitoring (VHM) is an ongoing project at Volvo Cars where they measure, amongst other parameters, inhalation and exhalation through a device called Respiratory Inductance Plethysmograph (RIP), on drivers. RIP measures changes in the cross-sectional area of the chest and abdomen. When the driver is in motion, such as when she is turning the vehicle, the cross-sectional area changes and noise in the RIP signal may arise.The noise results in a large number of manual adjustments in the analysis of the RIP signal, which is very time consuming and the validity of the device for measuring inhalation and exhalation is questioned.The purpose of this study was to improve the efficiency of the analysis of the RIP signal. The goal was to create a new data processing tool in Matlab that automatically detects inhalation and exhalation from a RIP signal with higher validity compared to the previous data processing tool.In this study, nine tests were performed on drivers while they were driving in different scenarios such as highway, country road and in city traffic. Inhalation and exhalation was measured using a RIP, a pneumotachograph with a tightly sealed facemask and a thermocouple placed between the nose and mouth, which was used as reference to the RIP.The result of this study was a data processing tool that automatically detects inhalation and exhalation with higher validity compared to the previous data processing tool.

Vectors based on lentivirus backbones have revolutionized our ability to transfer genesinto many cell types. Lentiviral vectors integrate into the chromatin of target cells and do not transfer any viral genes causing vector replication. Both of these features arecommonly used in gene therapy and have been used clinically in individuals sufferingfrom cancer, infections and genetic diseases. It has been discovered that T-cells can be genetically modified to be used as effective weapons against cancer: therefore virus mustbe produced to deliver the gene of interest into the T-cells. In this project, lentiviralvectors have been produced to transfer the gene coding for a chimeric antigen receptor(CAR) which is directed to CD19 on B-cells.

Vocal Cord Dysfunction (VCD) is characterized by paradoxical vocal cord movement during inspiration or expiration, and generally affects adolescents and predominantly women. Previous studies have shown a large inconsistency concerning terminology, definitions, etiology, assessment, differential diagnosis, co-morbidity and treatment. The purpose of this study was to map knowledge on and management of VCD in Sweden. The study was conducted as a written survey addressed to speech-language pathologists and physicians, and attained an answer percentage of 79 percent. The results showed that several professions were involved in the management of these patients, but no clear pattern of referral could be observed.

Syftet för denna studie var att studera förekomsten av postoperativa sårinfektioner hos patienter som genomgått kärloperation med inguinal incision under åren 2008 till och med mars månad 2013. Undersöka skillnader gällande riskfaktorer inom studerad patientgrupp för förekomst av postoperativ sårinfektion samt studera om patienter som utfört endovaskulär metod under samma vårdtillfälle oftare drabbades av postoperativ sårinfektion än de patienter som inte genomgått endovaskulär metod under samma vårdtillfälle. Metoden som användes var granskning av patientjournaler efter utifrån studien utvalda specifika operationskoder. Granskningen av de 54 patientjournalerna skedde med hjälp av egenmodifierad tidigare använd granskningsmall. Studieresultatet visar att förekomsten av postoperativa sårinfektioner hos den studerade patientgruppen uppgår till 22,2 %.

The aim of the present study was to investigate the effect of strategy for grouping calves into group pens with automatic milk-feeding systems on the calves' health and growth rate. The usefulness of changes in feeding behavior recorded by the computerized milk-feeder during periods of illness to identify calves with clinical diease was also studied. In the first experiment, 64 calves were moved in and out of group pens in a continuous way, while 46 calves were transferred into group pens until the the pen was considered "full". The calves in the latter groups were then held together until weaning. It was found that calves in the fixed groups grew approximately 100 g / day more compared to the calves in the dynamic groups. Signs of clinical respiratory disease were less frequent in this group, while the incidence of diarrhoea was slightly higher. In the second experiment health parameters, milk consumption and feeding behaviour was recorded daily for 46 calves.

Syftet med studien var att öka kunskapen om och förståelsen för hiv-smittade narkomaner i kriminalvård. Den övergripande frågeställningen löd; Hur beskriver ett mindre urval av hiv-smittade narkomaner i föremål för kriminalvård sina tankar och känslor kring sin sjukdom och sin livssituation? Studien var av kvalitativ design och den vetenskapliga positionen av hermeneutisk karaktär. Det empiriska materialet bestod av intervjuer med fem hiv-smittade narkomaner i kriminalvård. Tre teman var grundläggande i intervjuerna; Tankar, känslor och reaktioner kring hiv-diagnosen, Existentiella frågor, drivkraft och copingstrategier samt Bemötande i och utanför kriminalvården.

Background: Vaccination is an important part in cats? welfare. It both helps to prevent the individual cat from catching a disease or lessen the symptoms of it, and protects the entire cat population from an epidemic. It is the cat owner who makes the decision to vaccinate or not. Understanding the cat owners? perspective regarding vaccination may improve communication between the owner and the veterinary nurse, which may lead to a higher vaccination rate among cats.

Staphylococcus aureus belongs to the normal flora. Many healthy people are colonized by the bacterium mainly in the nose but also on the skin and on other mucous membranes without showing symptoms. After damage to the skin, the bacterium can enter the wound and cause infections. Methicillin-resistant S. aureus (MRSA) is resistant to b-lactam antibiotics such as penicillin and methicillin.

The average length of life is increasing in the western world, hence the older population is growing. A common health problem among the elderly is malnutrition. Malnutrition causes decreased body strength and is associated with an amplified risk of infections, depression, fractures and increased mortality. The health care system is therefore faced with the challenge to prevent malnutrition among the growing population of elderly. This could be done by providing nutritious foods developed to meet the specific needs of elderly. The overall objective of this project was to test a healthy energy dense drink based on oats targeted for the elderly consumers as a strategy to prevent malnutrition among elderly.

Tuberculosis is one of many infectious diseases in the world and is responsible for a large number of human deaths each year. The cause is Mycobacterium ssp included in the tuberculosis-complex, there among Mycobacterium bovis and Mycobacterium tuberculosis. Infection with M. bovis causes bovine tuberculosis in cattle which in 90 % has a pulmonary location. Humans are infected mainly by milk from infected cows but also by close contact with coughing animals or by eating raw meat.