The WT1 gene is a complex gene originally known to suppress cancer in kidneys. Studies of WT1 knockout mice have confirmed the important role of WT1 in the pathogenesis of Wilms? tumour, a tumour which counts for 95% of all childhood renal tumours. In that case the WT1 gene acts as a tumour suppressor gene. Subsequent research has shown that the WT1 gene in many other cases acts as an oncogene, e g in leukemia or lung cancer (even though these cancer forms can emerge as a result of many other aetiological factors).

The purpose of this study is to make a qualitative evaluation of the MTFC-program (Multidimensional Treatment Foster Care) on the basis of six youth´s experiences of the program. The study will investigate what the youth experienced as positive and negative about the program as well as finding out what has helped them or inhibited them from the aim of getting out of their criminal lifestyle. A secondary purpose of this study is to make the youth´s voices heard in the research world. The research question is: Which factors in the MTFC-program have helped or inhibited the youth towards the aim of getting out of their criminal lifestyle? For this purpose, a qualitative research method has been used where semistructured interviews have been performed on six youth who have gone through the MTFC-program.

This paper deals with the opportunities for the technique of condensation, for wood fired household heaters, on the Swedish market. In this project the condenser is preceded by a scrubber and both energy exchange and separation of unburnt particles have been studied. The facility studied is connected to a wood stove at 30 kW. The tests would show that the effect from the stove never reached above 16 kW. This might be a result of the low temperature of the water going into the stove, from the condenser. In addition to this the wood was not of highest quality and the stove could have needed some maintenance before the tests.

NMD 100 is a notes and media dispensing machine, manufactured by De La Rue Ltd, located in Flen, Sweden. The customers, mainly bank offices, have expressed a need for a more comprehensive description of errors occurring from time to time in their machines. In order to acquire a BSc-degree in Computer and Electronics Technology at the University of Linköping I have carried out a diploma work, regarding new computer programs to fulfil the customers? wishes. The machine NMD 100 is connected to its PC through handshaking.

The Swedish mental hospitals existed for about one hundred years, the period around 1880-1980. The research is intended to be from a local setting perspective to study the local approach used to meet requirements from Furunäsets mental hospital principals 1960 - 1972, the effect this had on the care and treatment of mentally ill patients and how Swedish society's changing approach to mental health influenced the process. The results of the research showed that Furunäset searched for ways to meet the principals' requirements which often went against the patients? personal best. Furunäsets mental hospital strove to fulfill its institutional goals in them selves rather than giving patients the care and treatment they needed.

This thesis work has been carried out at the consultant company Pöyry Sweden AB in Norrköping, whom performs the task for E.ON heating Sweden AB, Händelöverket in Norrköping. The report shows methods to manufacture slurry consisting of fly ash and water. The slurry shall be pumped into several former oil storage rock shelters that E.ON has put into operation for the specific purpose. The ash mixture also develops hydrogen gas in contact with water.The work has aimed to produce different suggestions of methods and equipment that can be used for the objective. Mixing method and security issues were in centre while working with the suggestions.

Denna studie syftar till att beskriva patienters upplevelse av läkemedelsassisterad behandling för opiatberoende (LARO), även kallad underhållsbehandling. I studien undersöks hur upplevelsen av LARO är och hur den beskrivs utifrån två olika patientgrupper; de patienter med en mindre välfungerande behandling som dagligen går till mottagningen för att ta medicin övervakat och som lämnar urinprov två gånger i veckan, samt de patienter med en välfungerande behandling som går till mottagningen två gånger i veckan för att lämna urinprov men hämtar medicin på apoteket. I uppsatsen har sex patienter intervjuats om hur de upplever LARO. Uppsatsens resultat illustrerar bland annat upplevd brist på delaktighet och empowerment i behandlingen samt vikten av en god relation mellan patienter och personal på LARO-mottagningen. Studiens slutsats är att Patient empowerment bör vara grundstenen i all arbete med omvårdnad och behandling..

A renewed application for environmental permit for the Hovgården landfill in Uppsala shall be submitted before December 2004, therefore the municipality of Uppsala needs improved knowledge of the contents, mostly organic compounds in the leachate and they also want to find a method to minimize the emissions of these compounds. The purpose of this study was to find a practical and economical method based on chemical oxidation using oxidants. The oxidants investigated are Fenton's reagent, hydrogen peroxide, Oxypro, potassium permanganate and potassium persulfate. The study was made on untreated leachate and leachate that has been treated in an aerated dam followed by sedimentation dams collected from the Hovgården landfill, and alson on sludge water from sludge storage cells. The effects of the five oxidants have been established by analysing the UV absorbance at the wavelengths 253,7 nm and 260,0 nm at different pH values. The UV absorbance was used to indicate the amount of aromatic hydrocarbons in the water. Also analyses of iron and manganese were done after the experiments with potassium permanganate, hydrogen peroxide and Fenton's reagent.

For several years Uppsala University together with several companies has been involved in a WISENET project aimed at improving railway transport security. By placing a sensor system near the wheels of each wagon, the temperature of the bearings can be measured and transmitted to a collector placed centrally on the wagon. This in turn transmits the collected data to RFID receivers placed intermittently along the railway.As the signals are transmitted wirelessly, problems may occur as the antennas get dirty or coated with ice and snow. To determine the effects of these coatings, several tests were performed examining the reflection coefficient S11, the impedance Z11 and the efficiency eta of an antenna, and how they varied when various coatings were placed over the antenna. Examined coatings were ice, snow and water to determine the effects of weather, and various metal-based coatings: powdered iron both pure and partially oxidized, and iron ore granules.

The relationship between free trade and the environment is often considered conflicting and the debates surrounding it are infected. My thesis deal with this conflict and how environmental concerns are integrated in three regional free trade agreements, North American Free Trade Agreement, The common market of the southern cone (MERCOSUR) and Southern African Development Community (SADC). I point out how the organizations differ from each other in this respect and I present a possible explanation to why they differ. The explanation is founded on the theory of the environmental Kuznets curve and that environmental concerns will depend on which level of development the member states in the organizations have. To judge and rank the organizations I have composed a model based on a pre-existing description of the trade and environment conflict.

Running water-pathways have played an important roll in Sweden and frequently been manipulated. One profound change was made during the period of logging when streams were cleared from obstacles as big boulders, sharp bends and side-streams. Dams and different constructions gave control of the stream water and the streams became channel-like with a homogen structure. This interference gave problems for many fish populations and resulted in a shortage of feeding habitat, over-wintering habitat, spawning habitat, unnatural flow regimes, sedimentation, unnatural temperature fluctuations. Many of these historical changes of the watersheds are now subjects for restoration, ie., bring back the streams to what we believed it was before the change. However, what once existed in terms of complexity is now gone and difficult toreplace.

Background: Many elderly are feeling lonely and insecure in their homes; it?s difficult for them to cope with their life situation after discharge from hospital. There is therefore a need to get a deeper understanding of their situation and the need for action, thus possibly preventing a new hospital admission. Recent research shows that a better coordination is necessary when elderly are discharged from hospital and that the quality of the discharge is essential for how they cope at home afterwards.Purpose: To get a deeper knowledge of older people´s experiences associated with frequent readmissions to hospital.Method: A qualitative research approach was used trough interviews with open questions. Ten persons with an age of 75 years and older who had a readmission to hospital within one month was interviewed.

Diabetes mellitus is an endocrine disorder affecting a range of different mammals, including dogs, cats, horses and humans. Worldwide, 347 million people have diabetes, and the disease is an increasing burden on the world?s poorest countries. The disease is characterised by chronic hyperglycaemia and afflicted individuals experience increased thirst, polyuria and weight loss, sometimes despite increased appetite. Diabetes mellitus is either insulin dependent or non-insulin dependent.

Traditionally, rolling mills use emulsions based on a mixture of oil and water for lubrication. Since two years ago SAPA has been using (instead of oil) a synthetic lubricant so called conditional emulsion for hot-rolling of aluminum. This lubricant is water based and homogenous at ambient temperature, but switches to a two-phase system at heating above the cloud point.This project aims to validate and if necessary modify an existing HPLC method for quantifying two out of three key components (A, B and C) in the conditional emulsion. Attempts to develop a method to quantify the pH adjusting components, X and Y were also made. These two methods are required to optimize the lubricant.Due to the complexity of the components, it has been difficult to present a method for quantification, and HPLC with ELS detection was chosen after a long series of trials.

The dishwasher is a wide spread product that occurs in many households. It saves the user time,water and energy. When using a dishwasher instead of doing dishes by hand a lot of energy issaved.The importance of lowering the energy consumption does not only come from the consumerwinnings but also from an environmental point of view. Scientists are certain that the globalwarming comes from the emission of green house gasses that is created by human consumptionof oil, gas and coal.Dishwashers today are a lot more energy efficient than older dishwashers, but there are stillmargins to lower the energy consumption. The aim with this project is to investigate thedishwasher and it?s washing cycle, noting different phases and components that contribute towaste of energy.