Breast cancer is the most common tumor disease among women in Sweden. About 7000persons, having a median age of 65, are diagnosed each year with this disease. Withmammography screening, breast cancer can be detected in an early stage which improves theoverall survival (OS). 20-30 % of the breast cancer tumors are overexpressing humanepidermal growth factor receptor 2 (HER2), which is a protein that stimulates cell proliferation.Trastuzumab (Herceptin®) is a humanised monoclonal antibody that targets the HER2-proteinand prevent the signals for cell proliferation.Trastuzumab has earlier been used for treatment of metastatic breast cancer. In the year of 2007trastuzumab was approved for adjuvant treatment of patients who has been medicated withsurgery and/or radiation.The aim of this study was to investigate the effects of adjuvant treatment with trastuzumab inHER2-positive breast cancer patients.

Prostate cancer is the most common cancer in men. One type of treatment is internal radiation therapy, brachytherapy. This treatment requires the patient to lie completely motionless and in lithotomy position. The purpose of this study was to investigate the prevalence of pressure ulcers associated with brachytherapy in prostate cancer at the UniversityHospitalin Uppsala. Furthermore, the purpose was to identify the most common location of pressure ulcer and to examine whether there were any connection between risk factors and possible pressure ulcers.

This paper is about the extent to which simplified penetration calculations ofsmall-caliber projectiles is a useful tool for assessing the physical protectioncapability. The work should be seen as an attempt to create an accessible tool inthe form of a simplified equation that allows for a better and safer use of thenaval vessels. The tool will also be used at different levels so that decisions andinstructions could be clearer.Performed calculations show a very limited capacity of a ship's basic design interms of physical protection against the use of small-caliber projectiles.How do we know that the calculations correct? By verifying the calculations withpractical shooting tests, a substantial condition to answer the question will becreated. To shoot against a material with two different thicknesses estimated toproduce perforation and non-perforation is a good approximation of the equationusability in the context..

Abstract: This report covers primarily the work of documenting electromagnetic fields generated by one of the later parts in the electrical power distribution chain: The electrical substation, wherein 10 kV is transformed to 400 V for use by private consumers. Thus it is one of the most widespread and frequently occurring parts in the Swedish power grid and of particular interest, as electrical substations are found everywhere in populated areas, often in close vicinity to people and animals.The report deals with a number of formulated questions and/or hypothesis? stated at the onset of the work undertaken, theory that is relevant for the topics the report covers, the details of the field work undertaken and the following analysis of the readings, which in term provide answers for the questions stated in the beginning. It also covers what is the currently known short term and long term risks associated with electromagnetic fields in the power frequent spectrum and of varying intensity in the vicinity of humans.The analysis also provides recommendations and identifies several points to carefully consider when planning for new installations or replacements of some parts of existing installations.For enhanced reading comprehension there is, aside from sections with pictures and attached explanatory texts and templates, several graphs, one-line diagram and maps of the power grid among the appendixes to the rapport..

Strålbehandling är i dag en vanlig behandlingsmetod för cancer. Strålskador i form av hudkomplikationer är så gott som ofrånkomligt och drabbar ett stort antal patienter. Dessa hudkomplikationer är ofta till stort besvär och obehag för patienten. Än idag finns oklarheter kring hur dessa hudkomplikationer bäst förebyggs och lindras. Syftet med uppsatsen var att beskriva sjuksköterskans omvårdnadsåtgärder för prevention och symtomlindring av hudkomplikationer, samt vilka andra faktorer utöver strålbehandling som påverkar uppkomst av hudkomplikationer.

This master thesis encompasses an inventory of the older industrial community of Gimo. Investigations of the contamination situation for each industrial area were done. A risk classification according to the Swedish Environmental Protection Agency?s ?Method of Surveying Contaminated Sites?, phase one, followed. The risk classification was done on areas of Iron Work, a rockwool industry and a landfill. Gimo have had iron manufacturing from 1615 until 1945. Gimo have had two blast-furnaces and two smithies periodically.

I denna kandidatuppsats avlägsnas organiska föroreningar från vatten genom användning av textilier, vars yta belagts med nanopartiklar utav ämnet titandioxid. När titandioxid belyses med UV-strålning sker en fotokatalytisk reaktion, vilket i sin tur bryter ned bland annat bakterier och organiska färgämnen. I hopp om att finna ultimat vidhäftning mot textil passande titandioxid har olika typer av beläggningar studerats; akrylbaserade, sol-gel och slutligen en hybrid. Dessutom har fem olika konstruktioner av textila bindningar jämförts i syfte att undersöka dess påverkan på den fotokatalytiska effekten. Förorenade vatten är ett stort problem, både i utvecklingsländer och i industriella sammanhang.

A protection helmet for young people (3-7 years) in winter environment has been developed in this thesis. The result is a concept proposal for development at STIGA Sports AB in Eskilstuna. This thesis work has been performed during 20 weeks, for a Master of Science in Product and Process development at Mälardalen University Eskilstuna Sweden in September 2009 to January 2010. The helmet is shown as a CAD model with detailed solutions to the outer shell, interior and adjustability (in sizes 50-56 cm) which are the three focused areas in the development. Also a physical model in scale 1:1 has been developed and is shown in this thesis work.To achieve the best result possible the process started with an analysis of the market and the product.

På dagens fönsterglasmarknad har produkter med samma funktioner och utseende fått olika namn. Detta är förvirrande och gör det svårt för en person som ska beställa fönsterglas att jämföra olika tillverkares produkter med varandra. Rapporten är tänkt som en översikt på de olika fönsterglasen som finns på marknaden idag och även på sådant som kan bli aktuellt i framtiden. Den berör också sådant som kan vara av värde att veta vid användning av fönsterglas. Målgruppen är alla som kan tänkas ha intresse i ämnet - alltifrån hobbybyggaren till fackmän i byggbranschen.

Breast cancer is the most common tumor disease among women in Sweden. About 7000persons, having a median age of 65, are diagnosed each year with this disease. Withmammography screening, breast cancer can be detected in an early stage which improves theoverall survival (OS). 20-30 % of the breast cancer tumors are overexpressing humanepidermal growth factor receptor 2 (HER2), which is a protein that stimulates cell proliferation.Trastuzumab (Herceptin®) is a humanised monoclonal antibody that targets the HER2-proteinand prevent the signals for cell proliferation.Trastuzumab has earlier been used for treatment of metastatic breast cancer. In the year of 2007trastuzumab was approved for adjuvant treatment of patients who has been medicated withsurgery and/or radiation.The aim of this study was to investigate the effects of adjuvant treatment with trastuzumab inHER2-positive breast cancer patients.

A new FPGA suitable for space applications has just reached the market. To investigate whether there are any possible flaws or limitations similar to those previously seen on FPGAs, an evaluation has to be done. This master thesis contains the evaluation of this new radhard FPGA with focus on possible design limitations and package related electrical phenomena.Areas evaluated: Ground-/VDD bounce, Cross talk, Rise time sensitivit, Power cycling, Power consumption, Place and route tool, Radiation hardnessThis report contains all steps in the evaluation. From method to measurements, comparisons, theory, results and conclusions. In the evaluation work, special effort has been made to develop designs that really stress the FPGA to find potential problems.

The goal of this paper is to find out how solar cells can improve energy efficiency on-board M/S Sydfart. The paper is based on a number of energy measurements on board the M/S Sydfart. The solar surface is calculated by measuring the available space for installing solar panels. Global radiation data is taken from STRÅNG's database, the data is then used to calculate the theoretical power produced by the solar cells. Energy efficiency is analysed in two ways.

Photovoltaic Systems in Sweden has longbeen heavily dependent on subsidies and grants to bring in a profit for the investor. Production of excess electricity is a major reason for this as the compensation for excess electricity today is low. However, there are businesses that have an electricityneed that are particularly suitable for solar electricity. These businesses have an electricity demand when the sun shines the brightest and if the Photovoltaic System is properly scaled, the excess electricity can be minimized. A golf club is that kind of a business and this thesis aims to examinate the solar power potential for golf businesses in Sweden.Nine golf clubs was selected from different locations in Sweden.

Transdermal drug delivery, besides painfulinjections with syringes, has long been associatedwith small size particle pharmaceuticals, which candiffuse through the skin. This method of drugadministration has only been applicable on a smallnumber of drugs, where active molecules are smalland delivery time should or can be long.Other drug delivery options are oral administrationand injection with hypodermic needles (ordinaryhospital syringes). In oral administration thestomach and liver tend to dissolve the drug and theeffect becomes more difficult to anticipate, anddrug delivery rates difficult to control. Hypodermicneedles are used as a mean of drug injectiondirectly into the bloodstream. This method ispainful and risks infection due to tissue damageand skin penetration.One way to get a painless non-damaging techniquewith high delivery rate that still can delivery largemolecules is to manufacture an array of microscopichollow needles and equip them with a pumping unitthat delivers the correct amount of drugs.This thesis shows the technique and possibility ofmanufacture micromachined needles using low costtechniques of Ion Track Technology (radiation ofheavy ions creates porous materials), electrolessdeposition (non-current activated wet chemistrymethod of depositing metal) and electroplating.

The study aims to investigate the feasibility of small-scale electricity production with solar electricity systems, also known as PV (photovoltaic) systems, in Australia. Due to the global warming, sustainable energy has in recent years become an increasingly important issue, both internationally and in Australia. With one of the largest dependencies on fossil energy sources in the world, the country's abundant solar radiation is a possible solution to this issue.Both the technical and the economic feasibility of small-scale PV systems were investigated. On the technological side, the electricity generation, distribution and consumption systems were studied. On the economical side, the parameters that drive the profitability of a PV investment were investigated.