Report of diploma work conducted at the Swedish Radiation Safety Authority (SSM) as part of the bachelors program in Nuclear Engineering at Uppsala University.All nuclear power plants in Sweden are obliged to report any deficiency in their barriers or the defense in depth in obedience to SSM?s regulations concerning safety in nuclear facilities. In addition, there is an international system for reporting such events. The purpose of this thesis is to study the Swedish report system and to analyze the differences between Swedish and international event reporting.In the Swedish system, SSM?s regulations are effectuated by means of event reports classified as category 1-3, designed individually at each Swedish facility.

Breast cancer is the most common tumor disease among women in Sweden. About 7000persons, having a median age of 65, are diagnosed each year with this disease. Withmammography screening, breast cancer can be detected in an early stage which improves theoverall survival (OS). 20-30 % of the breast cancer tumors are overexpressing humanepidermal growth factor receptor 2 (HER2), which is a protein that stimulates cell proliferation.Trastuzumab (Herceptin®) is a humanised monoclonal antibody that targets the HER2-proteinand prevent the signals for cell proliferation.Trastuzumab has earlier been used for treatment of metastatic breast cancer. In the year of 2007trastuzumab was approved for adjuvant treatment of patients who has been medicated withsurgery and/or radiation.The aim of this study was to investigate the effects of adjuvant treatment with trastuzumab inHER2-positive breast cancer patients.

Prostate cancer is the most common cancer in men. One type of treatment is internal radiation therapy, brachytherapy. This treatment requires the patient to lie completely motionless and in lithotomy position. The purpose of this study was to investigate the prevalence of pressure ulcers associated with brachytherapy in prostate cancer at the UniversityHospitalin Uppsala. Furthermore, the purpose was to identify the most common location of pressure ulcer and to examine whether there were any connection between risk factors and possible pressure ulcers.

Abstract: This report covers primarily the work of documenting electromagnetic fields generated by one of the later parts in the electrical power distribution chain: The electrical substation, wherein 10 kV is transformed to 400 V for use by private consumers. Thus it is one of the most widespread and frequently occurring parts in the Swedish power grid and of particular interest, as electrical substations are found everywhere in populated areas, often in close vicinity to people and animals.The report deals with a number of formulated questions and/or hypothesis? stated at the onset of the work undertaken, theory that is relevant for the topics the report covers, the details of the field work undertaken and the following analysis of the readings, which in term provide answers for the questions stated in the beginning. It also covers what is the currently known short term and long term risks associated with electromagnetic fields in the power frequent spectrum and of varying intensity in the vicinity of humans.The analysis also provides recommendations and identifies several points to carefully consider when planning for new installations or replacements of some parts of existing installations.For enhanced reading comprehension there is, aside from sections with pictures and attached explanatory texts and templates, several graphs, one-line diagram and maps of the power grid among the appendixes to the rapport..

Strålbehandling är i dag en vanlig behandlingsmetod för cancer. Strålskador i form av hudkomplikationer är så gott som ofrånkomligt och drabbar ett stort antal patienter. Dessa hudkomplikationer är ofta till stort besvär och obehag för patienten. Än idag finns oklarheter kring hur dessa hudkomplikationer bäst förebyggs och lindras. Syftet med uppsatsen var att beskriva sjuksköterskans omvårdnadsåtgärder för prevention och symtomlindring av hudkomplikationer, samt vilka andra faktorer utöver strålbehandling som påverkar uppkomst av hudkomplikationer.

ABSTRACTMultiple sclerosis (MS) is the leading cause of adult disability inSweden. Hematopoietic stem cell transplantation (HSCT) can be used as a treatment option for patients with MS where the disease has an aggressive course. The treatment is preceded by high-dose chemotherapy which lowers the patient's immune system. It is therefore of interest to study infectious complications associated with HSCT in this patient.Aim: The purpose of this study was to identify infection problems in this population associated with HSCT, and to study differences in infectious complications between this group and patients diagnosed with lymphoma who have undergone the same treatment.Method: The study was a retrospective descriptive study with quantitative data. A medical record review was conducted.

Today there are no analgesic drugs approved to be used in goats. Drugs approved for use in other species are consequently being used without knowing the pharmacokinetics of these drugs in goats. The purpose of this study was to investigate the pharmacokinetics of the opioid butorphanol when given subcutaneously in goats. Subcutaneous administration might extend the half-life compared to intravenous or intramuscular administration. Eight clinically healthy, non-pregnant 6 months old female goats were used.

I denna kandidatuppsats avlägsnas organiska föroreningar från vatten genom användning av textilier, vars yta belagts med nanopartiklar utav ämnet titandioxid. När titandioxid belyses med UV-strålning sker en fotokatalytisk reaktion, vilket i sin tur bryter ned bland annat bakterier och organiska färgämnen. I hopp om att finna ultimat vidhäftning mot textil passande titandioxid har olika typer av beläggningar studerats; akrylbaserade, sol-gel och slutligen en hybrid. Dessutom har fem olika konstruktioner av textila bindningar jämförts i syfte att undersöka dess påverkan på den fotokatalytiska effekten. Förorenade vatten är ett stort problem, både i utvecklingsländer och i industriella sammanhang.

The main purpose of this study was to investigate the effects of the non steroidal anti-inflammatory drug (NSAID) meloxicam in connection with dehorning of goat kids. Six 2-3,5 weeks old dehorned kids were given daily intramuscular injections of meloxicam (0,5 mg/kg; MG) and five age-matched dehorned kids were given isotonic NaCl (NG) for 3 days. The study was randomized and double blinded. The behavior of the kids was studied one day before dehorning, on the dehorning day and three days after. Blood samples were collected each day before the treatment and analyzed for plasma concentrations of meloxicam, hematocrit, cortisol, progesterone and glucose.

In this study, the efficiency of a newly launched predatory mite, Amblydromalus limonicus, has been examined for its potential to use as a biological control agent in cucumber production. A. limonicus can be used for biological control of two thrips species, Frankliniella occidentalis and Thrips tabaci. Field trials were conducted in greenhouses of two conventional cucumber growers in Scania, the southern part of Sweden. The basic control agent used against thrips was the predatory mite Amblyseius swirskii. In selected areas, additional A.

Phenylbutazone has been discussed in the world of the equestrian sport several times and different countries have diverse opinions on its use in competitions. The progressive list that permits phenylbutazone with plasma levels up to 8 µg/ml was presented at the FEI General Assembly in November 2009. The list was voted to be accepted, but later several countries realized the consequences and after protests the list was rejected and is going to be discussed again at the FEI General Assembly 2010. In this literature study I have studied the relationship between the concentrations of phenylbutazone in plasma and the effects on lameness. The purpose was to establish whether the limit of 8 µg/ml phenylbutazone in plasma affects the equestrian sport.

Breast cancer is the most common tumor disease among women in Sweden. About 7000persons, having a median age of 65, are diagnosed each year with this disease. Withmammography screening, breast cancer can be detected in an early stage which improves theoverall survival (OS). 20-30 % of the breast cancer tumors are overexpressing humanepidermal growth factor receptor 2 (HER2), which is a protein that stimulates cell proliferation.Trastuzumab (Herceptin®) is a humanised monoclonal antibody that targets the HER2-proteinand prevent the signals for cell proliferation.Trastuzumab has earlier been used for treatment of metastatic breast cancer. In the year of 2007trastuzumab was approved for adjuvant treatment of patients who has been medicated withsurgery and/or radiation.The aim of this study was to investigate the effects of adjuvant treatment with trastuzumab inHER2-positive breast cancer patients.

A new FPGA suitable for space applications has just reached the market. To investigate whether there are any possible flaws or limitations similar to those previously seen on FPGAs, an evaluation has to be done. This master thesis contains the evaluation of this new radhard FPGA with focus on possible design limitations and package related electrical phenomena.Areas evaluated: Ground-/VDD bounce, Cross talk, Rise time sensitivit, Power cycling, Power consumption, Place and route tool, Radiation hardnessThis report contains all steps in the evaluation. From method to measurements, comparisons, theory, results and conclusions. In the evaluation work, special effort has been made to develop designs that really stress the FPGA to find potential problems.

The goal of this paper is to find out how solar cells can improve energy efficiency on-board M/S Sydfart. The paper is based on a number of energy measurements on board the M/S Sydfart. The solar surface is calculated by measuring the available space for installing solar panels. Global radiation data is taken from STRÅNG's database, the data is then used to calculate the theoretical power produced by the solar cells. Energy efficiency is analysed in two ways.

The retrospective part of this study evaluates the susceptibility patterns of bacteria isolated from blood in critically ill foals in Sweden. The most commonly obtained bacteria were Actinobacillus spp. (38 %) and Escherichia coli (27 %). Trimethoprim-sulphonamide (TMS) had good efficacy against most gram negative bacteria with the exception of Klebsiella spp. Among 17 Escherichia coli isolates 94 % were susceptible to trimethoprim-sulphonamide whereas all 24 isolates of Actinobacillus spp.