Diabetes mellitus is a rising epidemic throughout the world and there is currently great interest in quantifying the beta-cell mass (BCM) in vivo non-invasively. In the present experiment, the feasibility of in vivo imaging of the glucagon-like peptide-1 receptor (GLP-1R) in beta-cells was examined, using the positron emission tomography (PET) tracer [68Ga]Ga-DO3A-VS-Cys40-exendin-4 as a marker, in native pancreatic beta-cells of a porcine diabetic animal model and healthy controls. Eight Swedish high-health domestic pigs were randomly assigned to be either controls or made diabetic using streptozotocin (STZ). The experiment proceeded during eight weeks, starting with an acclimatisation period. Once the pigs had been socialised they underwent surgery for the insertion of a jugular vein catheter, allowing induction of diabetes with STZ, intravenous (i.v.) injections and stress-free blood sampling. Development of diabetes was confirmed by clinical examinations, blood glucose values and insulin-staining of pancreatic sections post mortem. The diabetic pigs were insulin treated and responded well.

Opioids are considered the "golden standard" in pain management for both humans and small animals, but is used less often in equine medicine - probably for fear of side effects. Are there any studies that suggest that side effects are a major problem, or is it lack of experience which is the greatest obstacle to use? As early as 1937 it was shown that morphine and morphine derivatives provide analgesia in horses. For species other than horses used opioids often both pre-, intra-and postoperatively. They relieve pain effectively and are often included in the anesthesia protocol.

The tomato is an important crop worldwide, and in recent years it has received great attention due to its rich content of carotenoids, which in studies indicate to have health benefiting properties. Many studies have been done in this area of research and in how to optimize the carotenoid content in tomatoes and tomato products. The objectives of this essay were to summarize present data in this field. The results were as follows:There are nine different carotenoids identified in tomatoes. Lycopene and ?-carotene are the ones that have been given the greatest attention.

The urban heat island is an area restricted to a city center where the temperatureis higher than its surrounding environment. The greatest temperature difference isfound at night when the weather is calm and the sky is clear of clouds. There are twomajor causes behind this phenomena and the first one is the use of energy forheating of houses. The heat leaks through the walls of the buildings and warms upthe surrounding mass of air. The second one is the use of building material whichstore the suns radiation on daytime and releases the heat during night.

In this Thesis the possibilities of designing a larger building that is very energy efficient in the sense that it would not need a conventional heating system are discussed. Solar radiation transmitted through the windows, internal heat from occupants, lamps and electric appliances inside the building and heat recovered from the ventilation system then have to be sufficient for the heating of the building. This study is of general interest since the property company, Akademiska Hus, plans to use this study as a first step in determining if this technique could be used in the future and thus be worth further investments. A building without a conventional heating system of the size investigated in this project has not yet been built.The energy needed for the heating of the building was simulated using VIP+.The conclusions from the study are that it is possible to build large buildings without any conventional heating system. This could be achieved in many different ways, for example by lowering the inside temperature or by using better windows and heat recovery system with higher efficiency.

This bachelors thesis was made forWallenius Water AB to develop a basisfor an Airpurifier prototype. Wallenius Water isone of the world's leading environmentaltechnology companies engaged inchemical-free water treatment based onUV-radiation. The thesis aim was toproduce a basis for a prototype that canbe used in three applications:Standalone, RAS systems and ventilationsystems. The work includes anintroductory description of the theorybehind AOP technology based on aliterature review on the subject. Asurvey of products currently on themarket and a product specification hasbeen used as the basis for thepreparation of a number of concepts inthis report.

The tomato is an important crop worldwide, and in recent years it has received great attention due to its rich content of carotenoids, which in studies indicate to have health benefiting properties. Many studies have been done in this area of research and in how to optimize the carotenoid content in tomatoes and tomato products. The objectives of this essay were to summarize present data in this field. The results were as follows:There are nine different carotenoids identified in tomatoes. Lycopene and ?-carotene are the ones that have been given the greatest attention.

The purpose of this study was to investigate how people with insecure employment affect the psychological contract in the perspective of workers' experience. The questions in this study were: how does a person with insecure employment perceive the psychological contract and what consequences dose an insecure employment have on the psychological contract. The study was a qualitative method with semi-structured interviews. The results showed that the absent relationship that existed between the participants and the employer was assumed to be affected by insecure employment. The result revealed that one of the consequences was falling confidence and less support to the employer as an effect of insecure employment and psychological contract.

The purpose of this study was to investigate how people with insecure employment affect the psychological contract in the perspective of workers' experience. The questions in this study were: how does a person with insecure employment perceive the psychological contract and what consequences dose an insecure employment have on the psychological contract. The study was a qualitative method with semi-structured interviews. The results showed that the absent relationship that existed between the participants and the employer was assumed to be affected by insecure employment. The result revealed that one of the consequences was falling confidence and less support to the employer as an effect of insecure employment and psychological contract.

The tomato is an important crop worldwide, and in recent years it has received great attention due to its rich content of carotenoids, which in studies indicate to have health benefiting properties. Many studies have been done in this area of research and in how to optimize the carotenoid content in tomatoes and tomato products. The objectives of this essay were to summarize present data in this field. The results were as follows:There are nine different carotenoids identified in tomatoes. Lycopene and ?-carotene are the ones that have been given the greatest attention.

This is a master degree thesis at Royal Institute of Technology (KTH) betweenÅngpanneföreningen and Programma. KTH is the examiner, Programma is the client andÅngpanneföreningen is mentor for this project.Programma has a product called TM1800 that has problems with EMC; the problem is thatthis product does only pass the CE-check with a small safety margin. This problem can besolved by reducing the radiation from the electric components in the product or by reducing offix base frame. In this degree thesis the focus is only on mechanical redesign.The main problems right now depends on the long distance between the screws, there is anisolating layer on most of the parts and the forces between the joints are too small. The mainfocus is to solve these three problems.The best solutions are when the whole base frame is more or less redesigned instead of onlyredesigning some of the connection points.

The aim in the study is to search for a deeper understanding of how parents experience a neurological diagnose of the child and how this affects the parenthood. Parenthood was seen in a systemtheoretical perspective as a social construction. The narrative method was used in two lifestory parentinterviews. The analysis was made from parenthood. The result formed stories about parenthood with children having neuropsyciatric functional disability who even came to be a woman?s struggle.

Apart from recognizing and neutralizing threats, antibodies also have the ability to regulate immune responses against their specific antigen. IgG administered together with erythrocytes is well known to induce >99% suppression. This has been used to prevent haemolytic disease in new-borns since the 1960's, but the mechanism behind it is still not completely understood. The effect on the primary response is well established, but its influence on induction of immunological memory is still heavily debated. In this study adoptive cell transfer of splenocytes to irradiated mice was used to survey the effect IgG has on induction of immunological memory without disturbance from the primary IgG response.

The study evaluated the Mutant Prevention Concentration (MPC) of Pradofloxacin on three Escherichia coli (E.coli) strains, 2 wildtypes and one first-step gyrA resistant mutant. We also measured the value of AUC (Under the Concentration)/MPC that prevents growth of resistant mutants. It is of importance to reach a concentration above MPC that prevent E.coli from developing resistance against the antibiotic.We used an in vitro kinetic model where we added bacteria? and antibiotic. The culture flask was attached to a pump with an adjustable pump-speed.

Objective: To study the evidence on physical activity (PA) as an effective preventive strategy for depression.Methods: A search of electronic databases was performed for articles between 2007 and 2012, both original research and review articles, concerning the link between PA and depression on children, youth and adults. Three reviews, five longitudinal and two cross sectional studies were included.Results:  PA reduced the likelihood of depression in many studies and a sedentary or inactive lifestyle increased the risks for mental health symptoms such as depression. One study showed that low PA in childhood increased the odds of depression as an adult and other studies on teenagers saw a connection and mediation between PA and self-esteem whereas physical fitness showed no mediating effect. Many of the studies and reviews point out the insecurity regarding the dose-response association and the difficulties in defining causality.Conclusion: PA might have a preventive effect on depression. Some evidence exist to support that PA in childhood prevents depression in adults.