Alternative splicing is a process that partly rejects the common definition of a gene ? that one gene codes for one specific protein. By variable combination of coding regions (exons) and exclusion of non-coding regions (introns), formation of several different mRNA-transcripts, and consequently several different proteins, can derive from the same gene. Alternative splicing is an important condition for the development of complex life forms, but it is also a highly sensitive process and inaccurate splicing is the cause of approximately 15 % of mutations that cause genetic diseases. This article presents four genes, BRCA1, BRCA2, ER? and ER?, and inaccurate splicing of these genes increases the risk of developing cancer, particularly breast cancer and ovarian cancer.

Syftet med denna kvalitativa studie var att undersöka vilken inverkan boendesegregation har på ungdomars utbildningsmöjligheter. Studien innefattade 15 vetenskapliga artiklar och rapporter som analyserades med hjälp av systemteori och Bourdieus teori om kapitalformer. Resultaten visade att den sociala omgivningen är en viktig faktor för ungdomarnas studieresultat. Bostadsområdets vuxna är viktiga som rollmodeller. Normer och beteenden i närmaste omgivningen spelar en viktig roll i ungdomarnas socialisering.

Den ökande stressen bland hälso-och sjukvårdspersonal uppmärksammas tid efter annan i olika medier. Omstruktureringar och upplevda neddragningar i vården har lett till högre arbetsbelastning, vilket i sin tur påverkat arbetsförhållandena och det psykiska välbefinnandet hos personalen i negativ riktning. Omvårdnaden skall ges i en anda av respekt och förståelse för den enskildes integritet, och den som är i störst behov av omvårdnad skall prioriteras. Syftet var att beskriva förekomstoch upplevelserav samvetsstress bland sjuksköterskor verksamma på kirurgiska vårdavdelningar på ett sjukhus i Sverige, med hjälp av instrumentet Stress of Conscience Questionnaire (SCQ). Studien,där 60 enkäter analyserades (svarsfrekvens 64,5 %),visadeatt sjuksköterskornaofta upplevdesamvetsstress i relation till sitt arbete.

Denna rapport ger en bild av vilka olika saker byggherrar i Sverigeanvänder sig av idag för att öka den sociala hållbarheten. De projektsom studerats är Bygga om Dialogen i Malmö, Älvstaden i Göteborg,Vivalla i Örebro och föreningen Byggemenskap.Genom att intervjua en person från varje område studeras likheteroch skillnader i hur man arbetat med den sociala hållbarheten vidbyggnation. I Malmö och Örebro studeras arbetet med att öka densociala hållbarheten vid renoveringsobjekt, hur får de hela områdensom länge haft ett dåligt rykte att bli socialt hållbara där stort fokusligger på att anställa långtidsarbetslösa.I Göteborg och i föreningen Byggemenskap fokuserar man på attföra in den sociala hållbarheten vid nybyggnation och hur vi kan byggahyresrätter som har en lägre hyra än nybyggda lägenheter i dagslägethar..

Abstract The main subject of this essay is conflicts at work and the effect it has on the employee´s health.  I can through various reports read that bad health at workplaces is too high and that conflicts are a reason. What can be done to the work environment so it will be better from a psychosocial perspective? Sweden has a regulation that makes the employer responsible to work for an improvement in the work environment; can these regulations be used in purpose to reduce conflicts?My first question concerns the possibility to establish preventive procedures in the workplace systematic work regarding to improve the work environment. My second question is about the obligations of the employer to attempt to reduce conflicts at the workplace and the third question regards the documenting and monitoring of conflicts and the preventing work to reduce them. The purpose of this essay is to clarify how conflict preventive work can be included in the Systematic work environment management.

The purpose of this paper is to find the true meaning to the Swedish word "sinnesträdgård" as a fenonomen. This paper concentrates on the Swedish use of the word, because the term has different definitions in other countries. Our choice was a phenomenological method after reading literature on, and in relevance with, the subject without finding an answer to the question. According to our six informants - a politician, a project manager, two landscape architects and scientists, and two occupational therapists, the concept has not yet been defined. The results show that a "sinnesträdgård" is complex and means several things, but the main purpose of the concept and place is to stimulate all senses. We have discussed how to distinguish the concepts "sinnesträdgård", design garden and health garden, from each other as they all stimulate the senses.

Should I/we move abroad or not? This is a question that surely many of today?s expatriate Swedes asked themselves and was probably largely debated by most. How does is feel to move back to Sweden? I have chosen to contact a number of expatriate Swedes and some that have returned, in order to receive answers to these questions.The aim with this thesis is to study the experiences and thoughts of people living in a different country as to were they were born and also those of people returning to Sweden. I have used a hermeneutic analytical method alongside a socio-psychological identity perspective when I studied the replies of my 69 respondents.

AbstractIn this study eight caregivers, all with long experience from working in nursing homes for people with dementia, were interviewed.  The aim of the study was to describe the caregiver?s experiences in caring for people with dementia and Behavioral and Psychological Symptoms of Dementia disorder. Data were processed by qualitative, inductive, content analysis. The results were presented in four categories: To connect, Two days are never the same, Being calm and giving time and All are needed. The result showed that caregivers met a variety of difficult and varied tasks in nursing.

Bakgrund och problemdiskussion: I dagens samhälle är det inte längre frågan om en organisation kommer drabbas av kris, utan frågan är snarare när och hur väl förberedd organisationen är för att kunna hantera den. Tsunamin som inträffade annandag jul 2004 var en kris av tidigare sällan skådat slag, den drabbade det svenska samhället i allmänhet och resebranschen i synnerhet. Resebranschen är starkt omvärldsberoende och dess aktörer kan aldrig vara tillräckligt väl förberedda på en kris. För att stå bättre rustad inför kommande kriser, bör organisationer efter en kris eftersträva att dra lärdomar av sina erfarenheter.Problemformuleringen för denna uppsats lyder: Hur kan researrangörer förbättra sin organisatoriska kompetens utifrån sina erfarenheter av en kris?Syftet med uppsatsen är:Att kartlägga researrangörernas arbete med crisis management och vilka delar av detta arbete som har förändrats efter Tsunamikatastrofen.

Purpose: The study examines the risk a rising from the acquisition of shares, and its relation to the expected return. We would like to see how a high-risk portfolio is related to a low-risk portfolio. Although studying the portfolios annual performance.Theory: The theories that have been used in the study are, Capital asset pricing model, CAPM and portfolio theory.Method: The study is based on a quantitative method, the time interval is from 2008 to 2010.The annual reports, historical stock prices for companies and the index are used to perform calculations based on the essay theories.Conclusion: The beta value has positive liner correlation with the expected return. When there are bad times in the world, the companies are negatively affected regardless of industry. The Portfolios developed in the same direction during the time period..

Earlier studies shows that democracy within the preschool is an important and on-going work, but could implicate certain consequences. For example that goals regarding democracy and influence in the preschool, rarely is done in practice but instead remains just words on a paper. It could also mean that the pedagogues lack education and knowledge within the area, but also how they react to the influence of children. Preschool is expected to be a place for all children, no matter what luggage the child is carrying. The luggage is filled with the life experience, the personality and in this case the needs that the child has. The needs could be anything from nearness to physical and psychological disorders that requires more pedagogical attention.

This paper examines difficulties that heirs to swedified sami persons experience when learning about how colonialism forced a lot of people to hide or dim their sami identity. The purpose is to examine what genealogy can mean for these people and how it differs from the ?regular? genealogy; what makes these heirs willing or not willing to call themselves sami and how the cultural traumas and family wounds can be understood as dark cultural heritage and how these can be resolved. With cultural heritage and history usage theories, Hall?s theories of hybrid identities, and Aarelaid-Tart?s trauma model, I have analysed material from six interviewees and some of my autoetnography to conclude that sami genealogy is an important factor in shaping a more complete and decolonized view of history and one?s identity, that descendants of samis won?t call themselves sami because of a lack of sami ?capital? but want to as a way of not letting colonialism win, and that cultural traumas and family wounds heal through talking about them ? not hiding from them. The dark heritage is a necessary part of the sami identity build. I have also concluded that sami identity have always been nuanced, there isn?t one correct way to be sami..

I denna studie testas tio hypoteser som relaterar till finansiell teori för att se hur väl teorin kan förklara skuldsättningsgraden i små börsnoterade bolag. De teorier som testas är avvägningsteorin (trade-off theory), hackordningsteorin (pecking order theory) samt teorier relaterade till asymmetrisk information och agentkostnader. Testen genomförs med multipel linjär regressionsanalys och de undersökta bolagen är samtliga bolag med färre än 200 anställda på tre av de mindre börslistorna i Sverige. Resultatet visar stöd för åtta av de tio undersökta hypoteserna och är i flera avseenden tydligare än i tidigare studier som testar onoterade små bolag eller ett bredare urval av bolag..

The purpose of this study was to highlight LGBT asylum-seekers experiences of expressing their sexual identity or gender identity in the country of origin and in the asylum process in Sweden. By interviewing people who got permanent residence in Sweden because of gender or sexual orientation in Utlänningslagen (2005:716) we have been able to explore their own experiences from expressing themselves. This study analyse these experiences from a social psychological perspective, from this analysis we aimed to obtain a deeper understanding of how the experiences from the country of origin affects on the experiences in the asylum process. This study shows that LGBT asylum-seekers often is facing negative reactions from the environment in the country of origin, these reactions can limit their possibilities to express their sexual identity or gender identity in the asylum process in Sweden. The negative reactions they experience in the country of origin have contributed to that many LGBT people internalize feelings of fear to express themselves, feelings that often stays when they come to Sweden to seek asylum.

Background: Pressure ulcer is a complication that arises often due to a lowered general condition. Pressure ulcer arise because of long term compressive load application. That?s why it?s of utmost importance as a nurse to work in preventive ways, as the pressure ulcer lead to physical, psychological and social consequences for the patient. Purpose: The purpose was to describe the patients experiences of living with pressure ulcer.