In situ sekvensering är en metod som kan användas för att lokalisera differentiellt uttryck av mRNA direkt i vävnadssnitt, vilket kan ge viktiga ledtrådar om många sjukdomstillstånd. Idag förloras många av sekvenserna från in situ sekvensering på grund av det kvalitetsmått man använder för att säkerställa att sekvenser är korrekta. Det finns troligtvis möjlighet att förbättra prestandan av den nuvarande base calling-metoden eftersom att metoden är i ett tidigt utvecklingsskede. Vi har genomfört explorativ dataanalys för att undersöka förekomst av systematiska fel och korrigerat för dessa med hjälp av statistiska metoder. Vi har framförallt undersökt tre metoder för att korrigera för systematiska fel:I) Korrektion av överblödning som sker på grund avöverlappande emissionsspektra mellan fluorescenta prober.II) En sannolikhetsbaserad tolkningav intensitetsdata som resulterar i ett nytt kvalitetsmått och en alternativ klassificerare baseradpå övervakad inlärning.III) En utredning om förekomst av cykelberoende effekter, exempelvisofullständig dehybridisering av fluorescenta prober.Vi föreslår att man gör följande saker:Implementerar och utvärderar det sannolikhetsbaserade kvalitetsmåttetUtvecklar och implementerar den föreslagna klassificerarenGenomför ytterligare experiment för att påvisa eller bestrida förekomst av ofullständigdehybridisering.

AbstractIn the fall of 2003 a project was started in the Swedish building sector that is called BASTA (the building sectors’ termination of especially harmful substances). The project is operated by the building companies NCC, Skanska, PEAB and JM, the Swedish Building Industry and the Swedish Environmental Institute IVL. The purpose of the project is to create a common environmental assessment system for the entire building industry and with the help of this system phase out the use of especially harmful properties from building products.In a large sense BASTA works like this; On the BASTA web site there is a database, to which a supplier can register the company and the company’s products. Only those products with a substance content that fulfil the demands of the BASTA system, is to be registered. As it is the supplier himself that carries out the registration of the company and the company’s products to the system, the BASTA-organisation annually controls that the companies that are registered in the database, fulfils BASTA’s demands.Since NCC is one of the companies that operates BASTA, BASTA is probably going to be the environmental assessment system that is recommended for the company in the future.

Bakgrund: Redovisning syftar till att ge en historisk bild av en organisation ? ett företag eller en koncern. Skillnaden mellan den bild som baserar sig på redovisningsprinciper (och regler) och en bild, vilken som helst, är jämförbarheten. Goodwillned-skrivningar skapar problem med just jämförbarheten. Det skäl som anges baserar sig på regler stipulerade i IFRS.

AbstractIn the fall of 2003 a project was started in the Swedish building sector that is called BASTA (the building sectors’ termination of especially harmful substances). The project is operated by the building companies NCC, Skanska, PEAB and JM, the Swedish Building Industry and the Swedish Environmental Institute IVL. The purpose of the project is to create a common environmental assessment system for the entire building industry and with the help of this system phase out the use of especially harmful properties from building products.In a large sense BASTA works like this; On the BASTA web site there is a database, to which a supplier can register the company and the company’s products. Only those products with a substance content that fulfil the demands of the BASTA system, is to be registered. As it is the supplier himself that carries out the registration of the company and the company’s products to the system, the BASTA-organisation annually controls that the companies that are registered in the database, fulfils BASTA’s demands.Since NCC is one of the companies that operates BASTA, BASTA is probably going to be the environmental assessment system that is recommended for the company in the future.

The role of the professional photographer is ever changing. The changes take place as the Swedish media industry itself, due to fluctuations in the economy, is forced to change. As the demand for printed news wane, the advertisers seek out other media and free newsprint & the internet take over large portions of the market, the newspaper industry is forced to cut issues and make drastic changes to stay in business. This changes directly affects the way news bureaus are organised and inevitably changes the working conditions of their employees. The two competing newspapers ?Arbetarbladet? and Gefle Dagblad? in the Gävle district were affected by this kind of change in quite a unique way.

The projecting time in the construction industry needs to become more efficient toshorten the amount of time it takes to project a build. One of the North's leadingconstruction company NCC constuction Sweden AB has developed a form ofcollaboration called ?NCC project studio? that they use in some projects today.My thesis consists in bringing forth the most important aspects of the collaborationform called NCC project studio. The point of this is to use my thesis to help thecompany develop a quality document that can assist them when starting collaborationbased on NCC project studio in the future.The conclusion of my thesis was that much of the focus needs to be on explaining tothe participants what NCC is aiming to gain from working with the NCC projectstudio and also which important parts that needs to be worked on..

A bioslurry reactor was built for the bioremediation of TNT contaminated waste from the demilitarization industry. The field test was conducted at Vingåkersverken in Vingåker, Sweden, to see if results from laboratory studies could be repeated in a full scale reactor. The goal of the project was to optimize the reactor to such a degree that it could be used to handle the waste produced at Vingåkersverken and also that this technique could be applied for remediation of contaminated soils. Unfortunately the samples taken during the full scale field test were destroyed by the shipping company and no analysis was possible. A later attempt by the Biorex research group has also been unsuccessful to reduce the amount of TNT using the bioreactor.

In order to convince, one must know which arguments are most suitable for the specific situation. But even if you think you know how others will react to your arguments, you may be wrong. Therefore, the purpose of this paper is to find out a way of examining to what extent informative text take account to the subjective views of their addressees. The theoretical framework is Blitzer's theory of the rhetorical situation, pragmatic theory of speech acts and their presuppositions, Burk´s theory of consubstantiality and phenomenographic theory of subjective perceptions. Methodologically, phenomenography has also been used as a guideline for selecting informants, collecting data and processing the interviews.

This master?s thesis concerns the performance of professional children?s theatre in public libraries. With qualitative interviews I have looked into how four children?s librarians and two theatre consultants appreciate professional children?s theatre, and furthermore I have looked into their view on the importance of theatre for children. My intentions have also been to investigate their views on the function and status of children?s theatre in public libraries and also the relationship between library and theatre activities for children.

The purpose of this thesis is to highlight the work with line extensions by companies in the media industry. To obtain this purpose a case study was performed to learn about Norrbottens Media?s actions regarding their new launch of the magazine Extra. Information was gathered through an interview and media observations and was analyzed and compared to previous studies on the subject. Results of this case study show that the main reasons for the company?s line extension were new trends on the market and that the company had unexploited recourses to make use of.

The investigation analyzed the implementation and application of the Swedish National Archives' new Process-Oriented Archives Description Model to activities of the hierarchical, function-oriented and decentralized university organizations.The basic reason why a new archive description has evolved is because documents are becoming more and more digital. It requires a new interpretation of how evidence is secured for their reliability and authenticity, and a new way of looking at provenance, for the purpose of describing and searching electronic documents. The new archive description model's logical structure is based on business processes.The relationship between the new archive description and a function-oriented organization's activities can be seen from the different outlooks of processes between archive activities and activities of the organization. It is also reflected in the modification that all universities have made ??of the new archive description model to be more flexible and pragmatic to fit a function-oriented organization.The relationship between provenance and process-oriented archive description is mainly the link between documents and business processes that produce them.

Bakgrunden för denna studie är problematiken kring beslutsfattande. Tidigare forskning visar att en individ dagligen fattar en mängd medvetna och omedvetna beslut. Dessa beslut faller sig olika utefter vilka erfarenheter, preferenser och känslor individen har och hur detta påverkar individen vid köp av dyra sällanköpsvaror. Syftet med studien är att identifiera faktorer och personlighetstyper som influerar köparens beslut gällande dyra sällanköpsvaror..

The forest industry is one of the most important industry branches in Sweden. Since the demand of high precision wood deliveries has increased, the demand on a well constructed forest road net also has increased. A good road net gives the wood-supplier competition advantages and also increases its service level towards its customers, lumber-mills and pulp-mills. In some parts of Norrbotten, the road net is still insufficient and not yet built out enough, and that is why it is important to know how to act and where to improve the road net in these areas. The purpose of this thesis was to create a work-model for long term road planning in areas with no road net or a not yet complete road net. The model has been created in an ArcGis environment, where a long chain of tools has been tied together with the program ?Model builder?.

Over the past few years the Swedish forestry industry has become increasing interested in direct seeding. Although, in practice, this interest has been restricted to pine seed, the knowledge and techniques that have been developed for pine seeding can readily be transferred to spruce. Direct seeding is a method that is of interest to the forestry industry since it can lead to lower regeneration costs, denser stands and better root development than the more conventional planting method. This study evaluated experiments that focused on direct seeding of spruce in the northern Sweden. Skogforsk set-up the experiments in Gideå and Sävar in 2003.

Very often the interesting variables are explained by several underlying variables and in statistical analyses it is common to study the relationship between variables and groups of variables. Because of this multivariate analysis is commonly used in both science and industry. There are two problem with both univariate and multivariate analyses. One is when the variables are correlated. The other is when the number variables of exceeds the number of observations which makes the matrices algebra used in the analysis impossible to execute.