Tumour development occurs to a large extent because of dysregulation of the cell cycle. Of particular importance are defects occurring in the G1 phase. The reason why G1 is critical is because of the influence of several signals (external signals as well as cyclins and cdks) on this stage. The G1 phase can be divided into two parts, G1pm and G1ps. Each part has its ?own? restriction point which needs to be passed in order to progress to S phase.

Since the Convention on the Elimination of All Forms of Discrimination against Women (CEDAW) was adopted in 1979 there has been evident progress in the area of women's rights in great parts of the world, although this progress is still foremost concentrated to the Westernhemisphere. In Argentina, the work with gender equality and women's rights set of strongly during the last decade. The country has ratified the Convention on the Elimination of All Forms of Discrimination against Women and the Inter-American Convention on the Prevention, Punishmentand Eradication of Violence against Women "Convention of Belem Do Para" but still women and girls are victims of structural discrimination and serious impunity of their rights on a daily basis.The current situation proves that the positive changes within the context of international and national law do not necessary reach out to the population to the same extent. In the light of the lacking popular involvement and knowledge of their rights, a different type of solution is desirable. Therefore it would be of interest to examinate the role of Non Governmental Organisations (NGO:s) when it comes to implementing human rights in the society and ?the every day life?.

This paper relates a debate on a book Vetenskapen och förnuftet (1986) written by the Scandinavian philosopher Georg Henrik von Wright (1916 - 2003). The book brings up fate of mankind, raising the question if human rational thinking and scientific achievements are threatening our very existence on earth. Shortly after the book was published, it was intensively debated in a leading Swedish newspaper Svenska Dagbladet. Some 20 leading politicians and scientists contributed with their criticism during spring 1987. The paper highlights this debate by writing reception history, describing how the book with its serious message was received by leading scientists of the time.

The following report is based on the graduate job course in CAD technician program year two. The work reflected in the report is done in collaboration with Hans-Erik Eldemark. This work includes the development of a progress bar for dishwashers.The execution of the thesis has involved a list of criteria with conditions and requirements, which after where weighted in a matrix. Subsequently, the product proposal was developed and has been divided into three categories, twist mechanisms, attachments and exterior design. Finally, suggestions have been designed in CATIA V5 and prototypes were produced using 3d-printing.

At the Women?s House in Örebro, a children?s project has started where the work method ?Oasen? [Oasis] model has been developed by two children?s educationists. The aim of this study is, with the ?Oasen? model as a starting point, to deepen the knowledge of (1) how to meet children?s central needs while staying at a Women?s House and (2) what the ?Oasen? model may contribute to the children. The theoretical framework consists of a cognitive approach to the progress of children experiencing domestic violence and a presentation of conceptions concerning children?s needs.

Arbetets syfte är att undersöka vad ett förebyggande arbete för att undanröja hinder och svårigheter för elevers läs- och skrivutveckling kan innebära. Fokus ligger på speciallärarens roll i detta arbete. De frågor som undersökningen besvarar är hur klasslärare och speciallärare kan beskriva ett förebyggande arbete, hur samarbetet kan se ut, hur man kan tillvarata speciallärarens kompetens samt vilka faktorer som kan ses påverka. För att besvara frågeställningarna har kvalitativa intervjuer med fyra klasslärare och tre speciallärare i grundskolan genomförts.För att analysera och tolka de data som insamlats har ett sociokulturellt perspektiv på lärande använts, tillsammans med tidigare forskning och litteratur kopplad till ämnet.Ur ett sociokulturellt perspektiv framträder kunskapen om elevers proximala utvecklingszon, samt användandet av medierande redskap och scaffolding som betydelsefullt för ett förebyggande arbete. Resultatet för undersökningen visar att förebyggande arbete kan ske på flera olika sätt, exempelvis genom tidiga insatser, genom att organisera undervisningen, genom att skapa delaktighet och genom att ge eleverna en positiv självbild.

InledningIFRS-regelverket infördes 2005 och det har påverkat fastighetsbolagens redovisning.Branschen har genom organet EPRA tagit fram egna mått som kan användas för utvärderingoch analys av fastighetsbolagen. Studien skall belysa dessa skillnader och forskningsfråganlyder: Hur påverkas redovisningens relevans när man fokuserar på branschspecifika mått kontramått enligt IFRS, för fastighetsföretag?MetodMetoden som används för att hitta intressant data att analysera heter ?Lens model?. Metodenskall avspegla hur en expert analyserar ett företag, först tittar man brett på företaget i sin miljö,sedan studerar man företaget enskilt för att till sist gå ner på enskilda poster i räkenskaperna.Teoretisk ReferensramHuvudteorin är agencyteori. Teorin skall förutse vissa beteenden som rationella individer gör nären individ är tillsatt för att maximera vinsten åt en annan.

 Denna uppsats undersöker två läroböcker avsedda för gymnasiets A-kurs i engelskämnet, Progress Gold A (2003) och Solid Ground (2003), i syfte att se vad de kan kommunicera ur ett genusperspektiv. De frågeställningar som behandlas är följande: Hur konstrueras genus i texterna i dessa båda läroböcker? Då läsaren inkluderas exempelvis i ett "vi" eller "du", förutsätts läsaren då vara antingen man eller kvinna, eller har detta inte någon betydelse? Hur förhåller sig resultaten till läroplanens mål om jämställdhet?Den teori och metod som ligger till grund för analysen har hämtats från det fält som kallas diskursanalys. Såsom den utformats i detta arbete kan metoden närmast beskrivas som en kvalitativ närläsning av materialet. Resultatet visar på att båda läroböckerna till stor del tycks reproducera genuskontraktets grundpelare, dikotomiseringen av manligt och kvinnligt samt hierarkin dem emellan som ger det manliga högre statuts än det kvinnliga.

This study examines how a couple of Swedish daily newspapers construct the hacker network Anonymous, with an aim to discuss its possible effects. The question was: In which ways is the network Anonymous constructed in a few Swedish newspapers?                      26 articles from four chosen newspaper were analysed, but because of many similarities in content, only 10 were chosen for deep analysis. With Fairclough's model of critical discourse analysis as chosen method, constructions varying from the images of heroes to villains were found as a result. The most common construction was that of Anonymous as a threat, which was most often exaggerated compared to what actions were actually described in the texts.

In order to attract talented consultants, Sigma, a consultant company, wanted an online game for recruitment. In the game, potential employees? skills could be tested to determine whether they are qualified for the job. This paper presents a general technique for creating such a recruitment game. The report generalizes the recruitment game to a level-based game for the web, where a player should be able to progress from one level to the next by solving a given problem.

Uppsatsen behandlar böckerna och filmerna om Arn och undersöker genom berättelserna vilka representationer av makt, positivt kapital och livsmål som gestaltas. Uppsatsen baseras på den teoretiska tanken att populärkultur innehåller representationer med budskap, värderingar, normer och föreställningar gällande vår verklighet och därigenom påverkar vår uppfattning om världen, vår plats i samhället, vår identitet och vår uppfattning om vad som är värdefullt, viktigt och sant..

The capacity to process and to remember information is a basic condition for language ability and for coming reading ability. Reading ability is strongly connected to phonological awareness, receptive vocabulary knowledge and working memory capacity. In what way hearing impairment in children affects development of cognitive skills and later on reading ability is an area that has attracted minor attention for research.The aim with this study was to investigate changes in cognitive skills and reading ability in children with mild or moderate hearing impairment after one year of progress and furthermore if any connections between any increases of the abilities were to be found. Comparisons were made with results from age adequate normal hearing children. Moreover prosodic ability on word-level was tested this year.

Crop efficiency in utilizing available nutrients is an important factor in increasing produc-tivity and reducing the environmental impact of agriculture. Nitrogen is the nutrient that plants need in the largest quantity and wheat, along with maize and rice, is the world's most cultivated crop. In this work, the Nitrogen Use Efficiency, NUE, during the major growth period, HTP, of twelve different spring wheat varieties, were examined. The NUE was calculated as the product of uptake efficiency of nitrogen, UN, and the conversion effi-ciency of nitrogen to biomass, EN. The purpose of this work was to find if there are varietal differences in NUE and its components among the twelve varieties and to link a high NUE to specific characteristics of the varieties.

This essay is about two Swedish folk musicians, Anders Rosén and Leif Stinnerbom, who have been playing two important rolls in the developing process of Swedish folk music, on their separate ways. The main part of this work is focused on the era called ?The Folk Music Vogue?, which was the era when my informants were in the limelight on the Swedish fiddler scene of the 70s.Our music culture is constantly lying under the change of progress and I find it interesting to reflect how these kinds of changes are affecting the role of the musician.In this essay I am reflecting on the different perspectives of the musicianship according to my informants and how they both are referring to their role as musicians. The purpose is further on to see how they have been relating to the change of progress on the field of the Swedish folk music during the 70s and up to this date. Throughout interviews with the informants I am analyzing their personal relationship to their life as folk musicians.

This essay is about two Swedish folk musicians, Anders Rosén and Leif Stinnerbom, who have been playing two important rolls in the developing process of Swedish folk music, on their separate ways. The main part of this work is focused on the era called ?The Folk Music Vogue?, which was the era when my informants were in the limelight on the Swedish fiddler scene of the 70s.Our music culture is constantly lying under the change of progress and I find it interesting to reflect how these kinds of changes are affecting the role of the musician.In this essay I am reflecting on the different perspectives of the musicianship according to my informants and how they both are referring to their role as musicians. The purpose is further on to see how they have been relating to the change of progress on the field of the Swedish folk music during the 70s and up to this date. Throughout interviews with the informants I am analyzing their personal relationship to their life as folk musicians.