Penicillin G (benzylpenicillin) is the most commonly used antimicrobial substance used in equine medicine today. Two forms of penicillin G are available for equine use; one form is the poorly soluble penicillin G procaine and the other is the very soluble sodium salt. Although penicillin has a wide safety margin and is considered to possess a good tolerance, reactions due to side effects are sometimes encountered, which commonly is named ?penicillin-shock?. The etiology behind penicillin shock in horses is not completely understood, but the most common reason is believed to be procaine toxicity.

A sample of milk inoculated with S. aureus was treated with penicillin, and Antipen (a new commercial product containing penicillinase) was added. To another sample with S. aureus and penicillin, formic acid to pH 5 was added, and to yet another sample, a combination of formic acid and Antipen was added. Controls with no penicillin were treated in the same way.

In veterinary medicine, penicillin is the most used antibiotic in Sweden. Two dosage forms of penicillin are available in Sweden for use in horses, sodium benzylpenicillin (Na-pc) and procaine benzylpenicillin (proc-pc). Proc-pc is the most used dosage form and is used for intramuscular administration which allows horse owners to treat an animal at home under veterinary instruction. Na-pc is only approved for intravenous use in horses. Penicillin is normally well tolerated by horses but a serious, sometimes life-threatening, adverse reaction called penicillin shock may occur.

The use of intramuscular injections of procaine penicillin G (bensylpenicillin procaine) in the horse is now and then associated with acute adverse reactions (penicillin-chock). The etiology is not yet clearly understood, but the theories are several. One possibility is that it can be caused by procaine toxicity. Procaine penicillin G is a salt which is quickly dissolved in plasma. Procaine is then metabolized by plasmaesterases to non-toxic metabolites, p-aminobenzoic acid (PABA) and diethylaminoethanol.

Södra Cell Mörrum is one of the five paper pulp plants that are included in Södra Cell, and the paper pulp that is produced here is not only sold to Swedish paper mills. Most of the paper pulp is exported to different countries in Europe. In the manufacturing process the plant needs different kind of process water and there are guideline values for how much copper, iron and sodium this water is allowed to contain. Analyzes of this water is in the current situation done with an atomic absorption spectrometric instrument (AAS-instrument) with a flame. Measurements done with flame-AAS of samples that have concentrations near the guideline values for copper, iron and sodium, are not reliable. The reason for not being reliable is that the quantitation limits of these metals are higher than the limit values.

Staphylococcus aureus is the most clinically important Staphylococcus species and is associated with high mortality in patients with positive blood cultures. S. aureus bacteria may cause a variety of disease manifestations ranging from minor skin infections to life-threatening conditions such as pneumonia, meningitis, osteomyelitis, endocarditis, toxic shock syndrome (TSS) and sepsis. This microorganism belonging to the gram positive cocci may also be part of the normal flora. In Sweden, penicillinase-stable penicillins are the primary alternatives to treat S.

Idag utförs många röntgenundersökningar med hjälp av kontrastmedel, det kan dock leda till kontrastmedelsinducerad nefropati (KMN). Natriumbikarbonat har visat sig kunna vara ett lämpligt hydreringsalternativ mot KMN. Vårt syfte med denna studie var att undersöka om natriumbikarbonat är ett bättre hydreringsalternativ jämfört med natriumklorid som profylax mot KMN för patienter med nedsatt njurfunktion. Vi formulerade tre olika frågeställningar utifrån vårt syfte. Litteraturstudien innefattar 21 vetenskapliga artiklar som vi funnit genom sökningar i olika databaser.

The escalating usage of pyrethroids has resulted in an increased awareness about resistance towards pyrethroids in insects. Pyrethroids inhibit voltage-sensitive sodium channels (VSSC) in nerve cell membranes and are composed of synthetic molecules based on pyrethrins present in pyrethrum extracts from Chrysanthemum species. VSSC are transmembrane proteins that are important for electric signalling over the membrane in insects. Mutations in the gene encoding the sodium channel have proved to be a common reason for resistance against pyrethroids. Pyrethroid resistance among pollen beetles is spread all over Sweden and also abroad and is increasing.

Akut metrit drabbar kor 1-2 veckorna efter kalvning med symtom som feber ?39,5º, nedsatt allmäntillstånd och illaluktande vaginala flytningar. Denna typ av livmoderinflammation står för 64% av den totala mängd antibiotika som används vid behandling av reproduktionsstörningar. Idag rekommenderas behandling med penicillin vid akut metrit baserat på klinisk erfarenhet, aktuell litteratur och branschens generella inställning till antibiotikaanvändning och resistensutveckling, men ingen fältstudie har tidigare gjorts i Sverige inom detta område. Bovint herpesvirus typ 4 (BHV-4) är internationellt känt för att ha påverkan på livmodern i samband med metrit. Viruset är spritt över stora delar av världen men har ännu ej påvisats i Sverige.

Staphylococcus aureus is the most clinically important Staphylococcus species and is associated with high mortality in patients with positive blood cultures. S. aureus bacteria may cause a variety of disease manifestations ranging from minor skin infections to life-threatening conditions such as pneumonia, meningitis, osteomyelitis, endocarditis, toxic shock syndrome (TSS) and sepsis. This microorganism belonging to the gram positive cocci may also be part of the normal flora. In Sweden, penicillinase-stable penicillins are the primary alternatives to treat S.

Staphylococcus aureus is the most clinically important Staphylococcus species and is associated with high mortality in patients with positive blood cultures. S. aureus bacteria may cause a variety of disease manifestations ranging from minor skin infections to life-threatening conditions such as pneumonia, meningitis, osteomyelitis, endocarditis, toxic shock syndrome (TSS) and sepsis. This microorganism belonging to the gram positive cocci may also be part of the normal flora. In Sweden, penicillinase-stable penicillins are the primary alternatives to treat S.

Staphylococcus aureus is the most clinically important Staphylococcus species and is associated with high mortality in patients with positive blood cultures. S. aureus bacteria may cause a variety of disease manifestations ranging from minor skin infections to life-threatening conditions such as pneumonia, meningitis, osteomyelitis, endocarditis, toxic shock syndrome (TSS) and sepsis. This microorganism belonging to the gram positive cocci may also be part of the normal flora. In Sweden, penicillinase-stable penicillins are the primary alternatives to treat S.

The term euthanasia is derived from the Greek terms eu meaning good and thanatos meaning death, "good death". The penetrating captive bolt is an effective method of euthanasia, when use of drugs is inappropriate. The horse becomes immediately unconscious and falls to the ground. First after the blood is emptied from the body the horse is dead. The use of injectable euthanasia agents is a rapid and reliable method of performing euthanasia. The aim is to stop the flow of oxygenated blood to vital organs and tissues. The muscle relaxants may be used either in combination wih or following an anaesthetic dose of barbiturate, their use use as a sole agent is totally inhumane.

Four different kinds of filter-materials with reactive surfaces have been studied concerning their capacity to absorb heavy metals in leachate from a municipal waste deposit. The heavy metals studied were: lead, cadmium, copper, mercury, chromium, nickel and zinc. The leachate contains high levels of dissolved organic carbon (DOC) and has a high pH-value along with a high buffer capacity. These characteristics of the leachate make it difficult to remove pollutants and require efficient filters. The filters that were examined in the report are blast-furnace slag with CaO, sand covered with iron oxides, olivine and nepheline.

Texture is an important soil property and accurate particle size analysis of soil texture is therefore crucial. There are a number of well-established and newly developed methods available for determining soil texture. In order to compare the results of these methods, the differences between them must be determined. The difficulties, problems and differences regarding texture class determination were examined through a study performed on forest soil samples. The study compared different methods (pipette, hydrometer and field methods) and two types of dispersing agents (sodium pyrophosphate and sodium hexametaphosphate (calgon)) commonly used for particle size analysis.