The RECK gene is a relatively new discovered gene with important implications for cancer research. The research has been primarily concentrated on the human gene with the ultimate aim to identify the invasive characteristics. Up regulated RECK is linked to significantly prolonged survival rates in patients with severe forms of malignancies. RECK is normally expressed in all cells of the body and has an important role in the balance between destructive and constructive features of the extracellular matrix. The RECK protein is a membrane-bound glycoprotein that inhibit matrix metalloproteinases which has the function of breaking down the ECM. There is a significant correlation between RECK gene expression and the formation of new vessels, presumably via the mediation of VEGF which is an important and powerful inducer of angiogenesis.

The aim of this thesis was to examine how role players experiences libraries and if the libraries are or can be an arena for activities that involves role play. A public library exists for everyone, but could nevertheless be viewed as a female sphere where women both borrow more books and visit the libraries program activities to a larger extent, compared to men. I asked the question whether men?s reason for choosing a different venue for information and culture was related to the libraries not being able to satisfy their needs. The theory of the thesis was Dorte Skot-Hansen, Casper Rasmussen Hvenegaard and Henrik Jochumsens model that states that the libraries can have four different functions and act as a venue for meetings, knowledge, inspiration and experiences.

The technical development is advancing at high speed and now the turn has come for the traditional paper to digitalize into the so called e-paper. The newspaper industry has started to investigate the future possibilities of publishing the traditional newspapers on e-paper. Today?s newspapers are mostly financed by advertisement incomes, which makes the advertisers important players, who must be taken into consideration at an introduction of the e-paper. Since the e-paper does not exist as a finished product in the market today, in this essay we look into what kind of functions or services that can attract advertisers to the e-paper on the basis of the experiences made with the breakthrough of the web-newspapers.

The aim of this paper is to take a critical look at retouching of medieval mural paintings inSweden. This is done by firstly examining the different methods of retouching, including thematerials used. Secondary it tries to answer the question of which intentions have guided theconservator?s decisions dealing with the retouching. The medieval mural paintings in Swedishchurches have three major functions today.

This report describes a Bachelor thesis work in which a robotised laser welding cell has been modelled and simulated for the purpose of making a presentation movie. The report shows that the work has been concentrated on making the movie from the modelling phase through the recording of the movie and ending up with the editing of the final presentation movie. A pre-study was made prior the Bachelor thesis work. In the pre-study a literature study was conducted about measurement and calibration of a welding cell. Measurement of almost all equipment in the entire cell was also conducted in the pre-study.

The aim of this study is to illustrate conceptions held by librarians and library and information scientists about weeding practices of printed books in public libraries. The study has been carried out by performing a series of qualitative interviews with librarians and by study of earlier research relating to the subject of weeding. The results have been analysed by utilizing a textual analysis method called idea and ideology analysis using so called dimensions to analyse and structure the results. The results indicate that weeding at Swedish public libraries is carried out by a mixture of objective and subjective methods, with certain statistical elements. Weeding procedures mainly appears to be legitimized according to what one refers to as knowledge of the local community, although lack of lending are cited from time to time.

The public libraries were quick to adapt to the changes that the Internet brought on, and today library websites are an important part of the public library. To meet the needs of teens today, the library website could offer a range of contents to make it an attractive place on many levels; both the academic needs as well as social and recreational needs should be addressed.The aim of this thesis is to evaluate public library websites for teenagers in Sweden, and to examine how well the websites address the developmental tasks and needs that teenagers have. The method used is website evaluation, one quantitative and one qualitative. A total of 60 public library sites for teenagers were evaluated, using 11 criteria based on Havighursts developmental tasks. The quantitative evaluation measured how many functions each website had per criteria, and showed that the majority of the sites had one or two functions for most of the criteria.

 In this essay the aim was to investigate how the EU is trying to function as a democracy promoter in three particular countries, the so called candidate-countries Croatia, Macedonia and Turkey. The aim was also to analyze if there exist any differences in how the EU functions in these countries as a democracy promoter with a focus on how acts of democracy promotion is taken place. In order to fulfil the purpose of the essay two questions were addressed, how does the EU perform in promoting democracy in the three candidate-countries Croatia, Macedonia and Turkey? And also, is it possible to identify any differences in how the EU functions as a democracy promoter in those three countries?The method used to fulfil purpose and answering research-questions was qualitative text-analysis.  The results of the study were that the EU does perform in a number of ways to promote democracy in the three countries. The main differences are that the EU is using primarily political tools in Croatia and Macedonia which are channelized top-down and economic tools in Turkey channelized mainly top-down to promote democracy.

Research shows that people with burnout experience a high degree of impairments in a range of cognitive functions including memory, attention and concentration. The overall aim of the present study is to investigate whether there is a correlation between subjective estimates of cognition and cognitive performance with objective tests in people with burnout with a focus on working memory and executive functions. Three specific questions were addressed; First, what cognitive problems are described and to what degree? Second, is the performance of executive and working memory tests related to self-reported cognitive problems? Third, are the self-reported cognitive problems related to measures of psychological distress? The study included 77 patients, 65 women and 12 men, with a mean age of 43.48 years. The results show that patients with burnout perceive themselves as having significantly impaired cognition in everyday life, which is clearly evident on the basis of the self-assessment forms PRMQ and CFQ.

This is a final project which makes up 20 credits at the Landscapearchitecture programme at SLU in Alnarp. The thesis is design based. My final project is comprised two parts; of a competition entry for ? A New Square in the Centre of Täby? as well as a theoretical study that derives from the competition proposal. The competiton itself was announced on March 1st 2007 with the final hand-in date on May 28th 2007. The program of the competition asked for a flexible urban square that offers a diverse range of activities that can be used during both night and day, all year around. I became interested in the term ?mutlifunctionality? and I went on to use the subject as a base for my design approach.

This master thesis project will describe and evaluate the interfaces between applications and Controller Area Network, CAN, interface boards from different manufacturers. The interfaces have corresponding functions but the usage of parameters is different. The simply communication of sending and receiving messages is more alike than the supplementary functions between the different interfaces. The CAN communication is more controlled by the CAN protocol and is therefore more alike. The evaluation shows differences and similarities between different interfaces and also difficulties and options to translate them.

This thesis investigates lacks in today?s use of the ERP-system Mapaz Affärssystem inthe production planning at Solna Pressgjuteri, and possible improvements. Today thedates calculated by the program to plan the orders are inaccurate and the ordersequence is not optimal, and therefore continuous manual corrections are needed.The approach was to study the program Mapaz to understand how it works, andidentify available parameters for input and output in the different tools offered in theprogram. By studying old lists of planned orders and relevant parameters in Mapaz forindividual orders, production groups, products and operations, the connectionbetween input and output parameters could be understood.Participating in planning meetings and discussions with the company behind theERP-system identified the current usage, desideratum and possibilities with theavailable tools. These were then matched to describe the reasons to the insufficientplanning and form possible actions for improvement.The work has showed poor understanding for the ERP-system and its functions, assome tools intended to assist the planning were not used, and some even usedincorrectly.

The purpose of this master thesis is to investigate what the users/visitors do at the Filipstads Bergslags Library when they are there. The questions we asked were "What do the visitors do when they are at the library?" and "How do the visitors give priority to the librarys services?" From these two questions we asked a third "How do the visitors view the library and its functions and what function do they see as the most important to them?" The method we used was a user study and we did this at the request of the management at the library. A questionnaire was constructed and handed out in a pilot study. We made some changes in the questionnaire before we started to hand it out at the library.

As IT service departments in organisations are becoming more complex and customised, the indirect costs are increasing in relation to the total costs. The difficulty of fully estimating and identifying the spread of the cost in the IT service department is increasing. As a result, firms tend to budget the business unit as a total cost rather than as a spread of defined costs. In order to deal with this challenge an ABC calculation will be applied. The Time Driven ABC model will be conducted in OMX´s Servicedesk unit within the IT services.

The aim of this master thesis was to examine a possible connection between chromatin functions and the DNA damage repair system, with the imprinted IGF2/H19 locus as a bait. Interactions can occur within and between chromosomes and it has been shown that H19 ICR on both alleles can communicate with alleles on other chromosomes. The methylation-sensitive insulator protein CTCF is bound on the maternal H19 ICR and acts as an insulator by blocking the IGF2 promoter to access its enhancers. This is possible by formation of loop structures by CTCF that enables intra and inter-chromosomal interactions. CTCF is poly(ADP-ribosyl)ated by PARP-1 when it is bound to H19 ICR.