Background: Chemotherapy and radiation resistance are major causes of failure in cancer treatment. The response to treatment in cancer cells depends on several mechanisms and pathways such as Janus kinases-signal transducers and activators of transcription JAK/STAT pathway. STAT1 was the first described transcription factor in the STAT family. STAT1 is activated by stimulation of signaling proteins such as type II interferon (IFN- ?) and the activated STAT1 translocates from cytoplasm to nucleus.

The main objective of this study has been to explore how art therapists experience the visual art´s that can be used in the promotion of health among people with depression - and anxiety disorders. The concept of SOC- sense of coherence has been a central term and a link between imaging and SOC were identified in the study. The underlying method in the study was a qualitative form, where semi-structured interviews were used. Through a strategic- sample five female art therapist were contacted, who all came to participate in the study. The study is essentially based on hermeneutical method and the analysis of interview material has been analyst by using thematic analysis.

Netadmin Systems är ett Linköpingsbaserat IT-företag där huvudprodukten NETadmin är ett Operation support system/Business support system (OSS/BSS) som i huvudsak används i öppna nät för bl.a. kund- och lagerhantering, provisionering, övervakning och ärendehantering. Ett växande behov finns att göra det möjligt att använda övervakningssystemet via mobila enheter för att kunna felsöka och hantera driftstörningar effektivt.Syftet med rapporten är att undersöka hur övervakningssystemet kan göras tillgängligt på Android samt att ta fram en prototypapplikation för hantering av grundläggande övervakning. Genom fallstudien som har genomförts har slutsatsen dragits att Netadmin API är lämpligt för kommunikation via mobila enheter men att API behöver vidareutvecklas med ytterligarefunktioner. De viktigaste av dessa har implementerats och arbetet har även mynnat ut i en applikationsprototyp för Android.Genom utvecklingen av denna applikation ges Netadmins kunder möjlighet att hantera övervakningssystemet via mobila enheter..

Neurography is the most objective and reliable measure of the peripheral nerve function, and it is used to diagnose both local and generalized neuropathies. Neurography can measure both motor and sensory nerve functions. The principle for sensory neurgraphy is to stimulate over the nerve and record proximal or distal from the stimulated electrode.At the Department of Clinical Neurophysiology, University Hospital Uppsala, a problem has been identified, in that young adult patients tend to show unexpected abnormal neurography values in relation to the expected, indicated by the reference limits, without clinical correlates. This concerns foremost the sensory amplitudes in median and ulnar nerves. The hypothesis is that the requirement of young adults? amplitudes is too high.

This Masters thesis concerns how library and preschool can cooperate in supporting childrens language development and especially that of bilingual children. We have investigated how librarians and preschool teachers different competences can complement each other to gain the best result in work with childrens language development. This study is based on qualitative interviews with four librarians and three preschool teachers. The answers from them have been analysed according to different categories. Our results show that both librarians and preschool teachers think that bilingual children need extra support and that it takes longer to learn two languages.

Studiens syfte är att undersöka om ett intersektionellt perspektiv är integrerat i de två metodböcker som materialet består av; BRYT! från RFSL Ungdom och Tjejgruppskompassen från United Sisters. Detta undersöks genom att en diskursanalys av metodböckerna utförs utifrån Ernesto Laclaus och Chantal Mouffes diskursteori. Även en bildanalys görs av en del av materialet som består av bilder. De teoretiska utgångspunkterna i studien är ett intersektionellt perspektiv på genus, samt de teoretiska antaganden som ligger titt grund för diskursteorin. Resultatet visar på att ett intersektionellt perspektiv existerar i BRYT!, men är frånvarande i Tjejgruppskompassen..

The purpose of this study is to investigate? how a professional librarian can support the work with pupils, age six to twelve years, in their reading and linguistic development? how the conditions at the school have to be for this to become possible? what kind of attitudes the teachers have, and how they relate to the impact of a librarian for the pupils reading and linguistic development.The methods used are analyses of steering documents concerning school libraries and analyses of the means of the local school culture. The latter has been carried out by literature studies and through interviews of eight teachers and two school librarians. The result of the interviews showed a limited insight into how a professional librarian can support and assist teachers and pupils in the work with reading and linguistic development. They also showed the influence of existing traditions and local school culture for the use of a librarian?s services, and also how all the teachers, once they have become used to the services a librarian can provide, now find their support invaluable.

Play is an important part of children´s everyday life, it is through play children develop. Play occurs a lot in kindergarten and in this study, the aim is to examine how play activities play is used in preschool teaching and the role of the teacher´s in the play. Video recordings of play activities done and qualitative methods (conversation analysis) has been used to analyze the video recordings. The results of this study show that play are widely used as a pedagogical tool in preschool. It is through play children develop.

In today?s technological society, there are increasingly less physical demands on the locomotor system. However, despite that notion strength and function in the hand?s complex biomechanical system are in fact both needed to cope with daily life. The grip function is a main function in the hand and is used in many examples of scientific research, for instance when assessing physical health and predicting the probabilities of premature mortality.

Background: In Sweden the healthcare has moved from the homes to the hospitals, as the system has developed. Parents were not allowed to visit their children when they were hospitalised in the past. It was noticed in the beginning of the 20th century that it might be harmful for the children to be left without parents at the hospital. Today it is considered a fact that the parents should stay with their hospitalised children and the healthcare is based on a family-centered care. Aim: The aim of this literature study was to elucidate parents experience when having hospitalised children.

Aim: The aims of this essay were first to see if there were any factors that could have an inpact on participating in supportive care groups and activities after a prostatic cancer diagnosis. The second aim was to examine what kind of support the patients would chose. Methods: Data was collected with a survey handed out to the prostate cancer patients visiting the urologist reception at the hospital in Uppsala, during two weeks in the fall of 2011. Main Results: Men show very little interest in participating in supportive care groups and activities. When asked to chose which kind of support they could consider, individual sessions and group sessions were the most common choice. Conclusion: Men diagnosed with prostate cancer chose not to participate in supportive care. Further studies are required to determine what may be the reason to that..

The role distribution between designers and product coordinators and the system support between these roles are adapted according to the method of working that product models primarily are created for production and after sales market. At the same time models are also created to support a cross-functional way of working. This means that product structures exists on paper and as CAD-models before they are created in Scanias PDM-system environment which leads to unnecessary work and to information not being shared as early as it should be possible.A theoretical study has been performed with the purpose of understanding the problems and to create a foundation for improvement suggestions. Representatives from both roles have been interviewed together with other individuals with insight in the collaboration. A minor study concerning the roles of interests? collaboration at Volvo CC was also performed to be able to relate the study to another company.

In today?s technological society, there are increasingly less physical demands on the locomotor system. However, despite that notion strength and function in the hand?s complex biomechanical system are in fact both needed to cope with daily life. The grip function is a main function in the hand and is used in many examples of scientific research, for instance when assessing physical health and predicting the probabilities of premature mortality.

The aim of this study is to examine the word acquisition, focusing on the nouns and word exercises, in two Swedish textbooks for German in the upper secondary school. The chosen method for investigating the nouns was corpus analysis. The noun frequency and distribution in the textbooks were analysed and discussed in relation to research in second language acquisition. The Involvement Load Hypothesis by Batia Laufer and Jan Hulstijn was used to examine the exercises in the textbooks. The study showed that most nouns only occurred once in the textbooks, but the most frequent nouns were well spread in the textbooks.

Den här studien undersöker ett integrationsprogram i Falköpings kommun i Sverige. Studien visar integrationsprogrammet ur en vetenskaplig synvinkel och undersöker hur framgångsrikt programmet är, baserat på programmets syfte, som är att öka självförsörjandegraden bland invandrare i Falköping. Syftet med denna studie är att om möjligt kunna förbättra och förändra det pedagogiska arbetet i integrationsprogrammet i Falköping, och därmed öka chansen till självförsörjning för deltagarna i integrationsprogrammet. Deltagarna i integrationsprogrammet har också gett sina synpunkter på de pedagogiska insatserna genom en enkätundersökning och några av deltagarna har också deltagit i personliga intervjuer. Resultatet av studien visar att kommunens måluppfyllelse är god.