Propofol is an intravenously administered, hypnotic and short- acting pharmaceutical. One common sideeffect (>1:10) and therefore a disadvantage with propofol is the local pain that arise when the initial injection is given. Why the pain arise is not clearly understood. A majority of different pharmacological treatments, different doses and combinations, alternative administrations methods and physical interventions have been tried to reduce the pain when injection of propofol is given. One important task for the nurse is to relieve pain for patients.

Background: Osteoarthritis is understood to be a common cause of pain and dysfunction in cats; however there are few validated pain assessment methods for chronic pain in cats. In order to design a proper pain questionnaire, it usability need to be tested in both sound and sick cats. Aim: The aim was to investigate the usability of the pain questionnaire ?Lifestyle changes in cats? by compiling the results from the pain questionnaire reflecting the lifestyle in 30 healthy cats and compare it to the results from a clinical examination, as well as proposing improvements and additions to the questionnaire based on a literature review. Material and method: 30 healthy cats participated in the pilot study; the pet owner filled out a pain questionnaire with 16 questions regarding their cat´s behavioral and eventual changes in behavior and physical function. Thereafter the cat walked over a pressure measurement mat and finally underwent an orthopedic-directed clinical examination. The literature was found on Web of Knowledge, PubMed, Sciencedirect, and Google Scholar and also with the help of my supervisors.

Background: Multiple myeloma is a malignant incurable cancer disease associated with severe chronic pain. The nurse has several important roles in the management of patients with multiple myeloma. This study focuses on nurse´s roles including the caring of Pain relief.Aim: The aim of this study was to elucidate the nurse?s role in giving care to patients with multiple myeloma and associated chronic pain.Method: This literature study was based on scientific articles.Results: The nurse is in a key position to facilitate ongoing adequate pain and psychosocial assessment of patients with multiple myeloma. The study presents ways of relieving pain and suffering via different ways of caring management.

5-hydroxytryptamin (5-HT) is biochemically derived from Tryptophan. Kynurenic acid and quinolinic acid are also known metabolites of tryptophan. 5-HT is considered to play a role in depression and today selective serotonin reuptake inhibitors (SSRIs) are used for treatment of depression. 5-HT may also play a role in pain perception. The aim of this study was to investigate whether a supplement of tryptophan may affect conditions such as depression and/or pain.

Opioids are considered the "golden standard" in pain management for both humans and small animals, but is used less often in equine medicine - probably for fear of side effects. Are there any studies that suggest that side effects are a major problem, or is it lack of experience which is the greatest obstacle to use? As early as 1937 it was shown that morphine and morphine derivatives provide analgesia in horses. For species other than horses used opioids often both pre-, intra-and postoperatively. They relieve pain effectively and are often included in the anesthesia protocol.

One third of all Swedish people will suffer in cancer. Pain is a common symptom in cancer patients. The pain is subjective and includes several dimensions. The dimensions of pain are the physical, psychological, social and spiritual. This is a literature review and the aim with this study was to identify the pain experience in patients with cancer receiving palliative care.

Touch that is performed in a sensitive and gentle way can be a good complement in caring. To be stricken with illness can involve that the individual feels powerlessness and to have no control over the own body. This could lead to both psychical and physical suffering. To strength health is one of the nurses' responsibilities and to touch can be one way. The aim of the study was to describe patients' experience of the effects of touch.

Background: Cancer-related pain is a major problem worldwide. Studies indicate that patients do not get an adequate Pain relief. This creates a large suffering and results in major problems for the patient and their families. In order to minimize this kind of suffering caregivers need to understand how cancer-related pain is experienced by these patients, what it does to them and how it impacts their daily life.  Aim: The aim of this study was to describe patients´ experience of living with cancer-related pain.

Background: Pressure ulcer is a complication that arises often due to a lowered general condition. Pressure ulcer arise because of long term compressive load application. That?s why it?s of utmost importance as a nurse to work in preventive ways, as the pressure ulcer lead to physical, psychological and social consequences for the patient. Purpose: The purpose was to describe the patients experiences of living with pressure ulcer.

ABSTRACT Introduction: One of the great difficulties that the nurse anesthetist encounter in their profession is to assess and estimate sleep depth versus signs of pain in the anesthetized patient. Based on a pre-operative appointment and the perioperative monitoring, an assessment of the patient is made. The experience that the nurse anesthetist has can make it easier to understand what subtile signs of the patient depends on. Purpose: With this in mind, the purpose of the pilot study was to try to find out if there are specific signs of pain during anesthesia and if the professional experience played a role. As a subsidiary aim the authors examined whether there were factors in the patient that the nurse anesthetist takes into account in the identification of pain during anesthesia.

Aim: The aim of this study was to investigate how VAS (Visual Analogue Scale) is used in the prehospital environment, and describe how patients 40 years and older with acute chest pain describe their pain with help of VAS. Further, to investigate how the literature describes other instruments to evaluate pain. Method: This was a descriptive study and used both literature and empiric material as foundation. The selection consist of the paramedics medical record from one emergency department, 100 men and 100 women with chest pain witch had been transported with ambulance to one hospital in middle of Sweden. A literature review was done in order to see what previous research recommends for pain rating scales.Results: The study showed that 71 (35 %) of 200 individuals pain were rated with VAS according to the guidelines for the ambulance department.

People with dementia often have difficulties expressing their needs. Untreated pain within this group can be manifested as depression, agitation or loss in appetite. It can be a challenging task for a nurse to estimate, treat and evaluate pain for people with dementia. With good knowledge and an empathic approach, nurses can often recognize and relieve pain amongst these people. Despite this, litterature often suggest that unrecognized and untreated pain is common within this group..

The aim of this study was to describe nurses? knowledge of pain. The method used was a systematic literature study. Information was gathered from the databases Blackwell Synergy, Academic Search Elite and Medline, and the keywords used in the search were: pain, knowledge, nurses and nurses.The result was divided into three subgroups; Insignificant documentation and evaluation. More education is necessary.

 Pain is common among women undergoing first trimester surgical abortions. At the postoperative unit, department of gynaecology, University Hospital, Uppsala, the goal is that 80 % of the women should rate pain as £ 3 on a numeric rating scale (NRS), when leaving the unit.The aim of the study was to investigate how rating was performed at the unit and to investigate patient?s perceptions of pain after having undergone first trimester surgical abortion.20 patients (74%) participated in the study. Ninety percent of the patients rated their pain as NRS £ 3 when leaving the unit. Seven patients (35 %) rated their pain as NRS > 3 directly after operation, and 2 (10 %) patients NRS > 3 when leaving the unit.

Assessing and measuring post-operative pain in all animals is a challenge, but doing it in small mammals, for example guinea pigs, presents an even larger difficulty. Validated pain scales developed for use in dogs in clinical practice are currently available, but no such scale has been widely accepted for use in guinea pigs in the veterinary setting. In this experimental study, six guinea pigs that had undergone surgery and anaesthesia were observed for behavioural changes that could be associated with pain. The six guinea pigs were also given pain scores with the use of Colorado State University Feline Acute Pain Scale (CSU-APSF), a scale which uses both behaviour when not handled, body tension and response to palpation to evaluate pain intensity. The six guinea pigs showed a number of different behaviours, for example rigid posture, fixed stare and ?wet dog response? (the body is vigourosly shaken), that could be associated with pain.