Diabetes mellitus is a rising epidemic throughout the world and there is currently great interest in quantifying the beta-cell mass (BCM) in vivo non-invasively. In the present experiment, the feasibility of in vivo imaging of the glucagon-like peptide-1 receptor (GLP-1R) in beta-cells was examined, using the positron emission tomography (PET) tracer [68Ga]Ga-DO3A-VS-Cys40-exendin-4 as a marker, in native pancreatic beta-cells of a porcine diabetic animal model and healthy controls. Eight Swedish high-health domestic pigs were randomly assigned to be either controls or made diabetic using streptozotocin (STZ). The experiment proceeded during eight weeks, starting with an acclimatisation period. Once the pigs had been socialised they underwent surgery for the insertion of a jugular vein catheter, allowing induction of diabetes with STZ, intravenous (i.v.) injections and stress-free blood sampling. Development of diabetes was confirmed by clinical examinations, blood glucose values and insulin-staining of pancreatic sections post mortem. The diabetic pigs were insulin treated and responded well.

Yeast and Clostridia is a problem in silage for farmers as contaminated silage may result in poor animal health and milk quality. Clostridia can produce toxins that, when consumed, acts as neurotoxins, it may also cause blown cheeses if the Clostridia contaminates milk. The purpose of this study was to investigate the cause, effect and interaction of yeasts and Clostridia in silage. Clostridia are microorganisms which are strictly anaerobic and consume carbohydrates and protein in the silage. Yeast is a fungus that is facultative aerobic and feed on carbohydrates in the silage.

Background: Myocardial infarction is the most common individual disease among people in the west world. In Sweden there are over 50 000 women and men who get myocardial infarction every year and about 40 % of them dies. Exercise training is one part of cardiac rehabilitation and since 1980 Sweden use the guidelines from that time. Aim: The aim was to review exercise-training modalities in cardiac rehabilitation after myocardial infarction and the physiologic- and psychological effects. Method: Facts were obtained by searching through the database PubMed for articles published from 1994 and ten years forward.

The purpose of this work has been to explore what ecosystem services a small green area in an urban environment can offer and whether specific trees can be used to maximize regulatory ecosystem services in a cultural-historical environment. Additionally, it investigates whether there is any difference in ecosystem services depending on whether these trees, or trees that better fit into the cultural-historical environment, are used. Through simulations and comparisons with existing trees in Pommerska tomten, Mariestad, Sweden, a pocket park within a national interest area, different hypothetical tree planting options are analyzed and evaluated. To measure ecosystem services, the website My-Tree, developed by the US equivalent of the Department of Agriculture, was used. By inputting data about the tree, such as location, species, vitality, stem diameter, and solar exposure, My-Tree calculates some of the ecosystem services the tree provides.

Abstract The accident in 1986 at the nuclear power station in Chernobyl, Ukraine, dispersed radioactive cesium over large areas of Europe. The half life of 137Cs is 30 years and this radionuclide also behaves like potassium, which means that it can easily be taken up by the vegetation or be adsorbed in to the structure of clays, principally illitic clays. When radiocesium decays ionizing radiation is emitted, which is harmful to humans that are exposed, either directly or indirectly through food intake. It is there-fore important to know what happens to the cesium that is dispersed into the environ-ment. In this project a simulation model was constructed to simulate the adsorption and transport of radiocesium in the soil and plant uptake.

The EU Water Framework Directive has led that management follows the boundaries of natural catchments.The Swedish waters suffer from a nutrient overload that originates mainly from diffuse sources such as agriculture and the subcatchment of Hackstabäcken in Vallentuna Kommun, just north of Stockholm, has been chosen for this study because of its high nutrient load and because it has undergone obvious changes in land use through the years.In this study, the land use in 1902 is compared with the land use in 2011 in order to investigate if it has influenced the ability of the landscape to produce ecosystem services related to nutrient removal. These services will continue to be produced as long as the system is stable and resilient, but when landuse changes and manure from horses increases it will lead to disturbances that can convert a system from one regime in to a completely different one. That will result in loss, or degradation, of ecosystem services such as denitrification, phosphor sedimentation and adsorption, vegetation uptake and infiltration.The results of this study are based upon area calculations of landuse from old maps from 1902 and 2011. Through these maps it becomes clear that the forests in Hackstabäcken, has increased with 170 ha together with an urbanization of 311 ha, at the same time as wetlands and arable land has diminished and lakes has suffered from reductions. Wetlands have been reduced with 76 ha and the ones remaining are of insufficient quality from a nutrient removal perspective.Data from 1902 and 2011 regarding number of horses and bovines indicated a decrease in bovines and an increase in horses.

SammanfattningIntroduktion: I dagens arbetsliv och samhälle har individen blivit allt mer stillasittande och minskat mängden motion med risk för sämre kondition trots att detta är en känd riskfaktor för sjukdom och nedsatt arbetsförmåga. Syftet med denna studie var att studera konditionsnivån hos kontorsanställda i förhållande till BMI, kön och ålder.Metod: En kvantitativ tvärsnittsstudie har genomförts baserad på data från hälsoundersökning där BMI, kön, ålder och konditionstal undersöktes. 100 personer deltog i studien, varav 33 kvinnor och 67 män i åldern 25-63 år.Resultat: De kontorsanställda hade en god syreupptagningsförmåga på i genomsnitt 37,3 ml/(kg x min) och låg över det rekommenderade konditionstalet 35 ml/(kg x min) för kontorsarbetare. Kvinnorna i gruppen hade bättre konditionstal än männen. Medelålders kvinnor (41-50 år) hade något lägre konditionstal än yngre (25-40 år)och äldre kvinnor (51-63 år).

In the production of pulp, paper and cardboard, a large amount of water is used daily. The water has to be purified in the internal purifying plant before it reaches the receiving body of water. In the biological purifying stage at the Stora Enso Skoghall mill, an aerated basin is used where the microorganisms, using oxygen, oxidize the organic material to carbon dioxide. The air is pumped from the bottom of the basin and the oxygen can then be transported from the air bubbles to the water through diffusion. The problem with aeration of waste water from the forest industry is that wood residues, such as fatty acids, are making the transport of oxygen in water more difficult.

Obese horses with insulin resistance are often also afflicted with laminitis. Horses with these symptoms are given the diagnosis equine metabolic syndrome (EMS). Signs of insulin resistance are excessive accumulation of adipose tissue on the neck, around the withers and on the dorsal area of the hindquarters. Insulin resistance means that the function of insulin is defective and does not stimulate glucose uptake by the cells in the body in the correct way. This will result in an increased insulin release.

Wood has always been an important material for people, and it is used for many applications. As for example, fuel for cooking and heating houses, construction materials and for constructing means of transport. Since wood also is a material that with time biologically degrades due to activity by micro organisms and wood fungi it is important to find ways to protect and further lengthen the life span of the material when in service. One method is to decrease the amount of water in the material by impregnation with an hydrophobic oil. The Linotech method which uses only pure linseed oil is one such possible method. The aim of this study was to investigate the possibility to at the same time impregnate and stain/colour wood samples of pine and spruce by using the Linotech method.

Oxygen consumption and carbon dioxide production are usual measurements within the sports and training physiology. The same measurements are also common when it comes to establish the amount of energy that is used during work and to establish the intensity of work. The volume of oxygen that is consumed contra the volume of carbon dioxide that is produced can be used to calculate the metabolic rate within the human body. This calculation shows the percent relationship between carbohydrates and fat in the metabolism. The first accurate method to measure the breathing gases for use in metabolic calculation was established in the early twenty century when the Douglas bag method was introduced.

It is important to construct or recreate different types of wetlands and study their retention of nutrients, since knowledge of their effectiveness in this matter is poor. In 2003 a wetland was constructed on an old meadow on the western shore of Lake Bornsjön in central Sweden. The main purpose of the wetland was to reduce the amount of phosphorus entering the lake, which is the back-up water supply for Stockholm when the city cannot obtain water from Lake Mälaren. Large areas around Lake Bornsjön consist of agricultural land and the nutrient concentrations in the inflows to the lake are usually relatively high (approx. 1 mg/l total nitrogen and 0.05-0.1 mg/l total phosphorus).

Chlorinated aliphatic hydrocarbons (CAH´s) were used widely within dry cleaning facilities and for metal degreasing until their toxicity was discovered. PCE is still used as dry cleaning liquid. Today CAH´s are found in soil environment at places where they have been used in the past. The CAH-concentration in trees growing on contaminated land has quite recently received attention as a cheap and effective way of assessing the extent of a CAH-contamination. The method has however, not been put into use in Sweden.The aim of the study has been to investigate whether the CAH-concentration in tree cores could be used to delineate the spread of CAH in a soil environment under Swedish conditions in different seasons.

I denna litteraturstudie granskades 4 vetenskapliga artiklar med syfte att undersöka patienters upplevelser av hyperbar oxygenbehandling (HBO behandling) för att lyfta fram vad man som omvårdnadspersonal bör ha i åtanke inför initiala behandlingar. HBO behandling är en behandlingsmetod där koncentrerad oxygen administreras till patienter. Behandling med HBO får ofta pågå under längre tid för att uppnå läkande effekter i exempelvis fall av hypoxiska svårläkta sår. Ett av de initiala problem som kan ge obehagskänslor är att behandlingen tar plats i tryckkammare, vilket för många är en främmande miljö. Flertalet patienter har av denna anledning valt att avstå ifrån behandling.

In the production of pulp, paper and cardboard, a large amount of water is used daily. The water has to be purified in the internal purifying plant before it reaches the receiving body of water. In the biological purifying stage at the Stora Enso Skoghall mill, an aerated basin is used where the microorganisms, using oxygen, oxidize the organic material to carbon dioxide. The air is pumped from the bottom of the basin and the oxygen can then be transported from the air bubbles to the water through diffusion. The problem with aeration of waste water from the forest industry is that wood residues, such as fatty acids, are making the transport of oxygen in water more difficult.