The ability to detect protein-based biomarkers, which are linked to different diseases like colorectal cancer, is very important as a diagnostic tool. Usually complex biological samples like blood are studied which will contribute to different technical issues when performing an assay. The aim with the project is to optimize and develop the high throughput protein detection technique Proximity Extension Assay, PEA, into a 96-plex panel, in hopes of discovering an expression profile for colorectal cancer. PEA was developed by Olink Bioscience and allows specific proteins in a sample to be quantitatively transformed into nucleic acid sequences that are subsequently detected and quantified with real-time PCR. Two proximity probes containing oligonucleotide sequences bind pairwise to target protein and when brought in proximity, a DNA polymerase will extend a hybridization arm from one probe over to the second forming a double-stranded DNA sequence that can serve as a template in real-time PCR.

Många faktorer påverkar den orala hälsan, däribland kosten. Idag finns många olika kosttyper samt livsstilar, och något som ökar i Sverige är den vegetariska kosthållningen. Syftet med denna litteraturstudie är därför att kartlägga vilken inverkan vegetarisk kost har på den orala hälsan. Artiklarna som användes i denna litteraturstudie hämtades från databasen PubMed, och studiernas referenslistor granskades kritiskt. Det upptäcktes också artiklar genom referenslistgranskningen.

Children and youth inactivity and sedentary at school is increasing. This means that some of the students have a significant unhealthy lifestyle with physical inactivity, which in turn implies risks of suffering from various diseases, including obesity, type 2 diabetes and cardiovascular disease, all related to a sedentary lifestyle. To prevent illness, it is important that children and young people early get a positive attitude towards physical activity.The purpose of this study was to study the causes of child and adolescent physical inactivity in school, based on teachers 'and parents' perspectives.A qualitative research has been selected. To achieve the study objectives, the author has conducted seven semi-structured interviews, with an appropriate choice of five teachers and two parents with children in school. Data was analyzed with a manifest content analysis.The results show that teachers and parents felt that physical activity is a protective factor for children's health.

The physical inactivity and other diseases related to ways of living in Sweden, affects a big part of Swedes, simultaneously as the society is more defined and marked by health promoting and by views that affects many people to actively make a difference in their lives. Physical activity on prescription is such an example of health promoting, which enlarges the conditions for a healthy life. Physical activity on prescription is also about that the individual should take the decision by herself to increase her physical activity or to get motivated to start a healthy life style alternative reduce the risk of getting sicker. The purpose of our study was to illustrate what the participants of ?fysioteket? thought about the work of fysioteket and if the physical activity on prescription has affected their motivation towards physical activity and their experienced health.

This study is about the use of textbooks in teaching English as a second language and about teachers? attitudes and opinions of using textbooks during lessons. The aim of the study is to receive a deeper understanding of the use of textbooks in English teaching and to learn about why teachers choose whether to use the textbook approach or not. The study contains an analysis of the textbooks the teachers in our study used. The analysis shows the actual content and the types of texts together with the design and the structure of the textbooks.

Sweden is getting an aging population and with this comes an increase in neurodegenerative diseases such as Alzheimer?s disease (AD). Bilingualism is also on the rise and this may result in an increase of bilingual people suffering from AD. Due to the linguistic deterioration associated with the illness people with AD, bilingual and monolingual, will be an increasing patient group with speech and language pathologists (SLPs). Word retrieval difficulty is an early symptom of the disease and several strategies to compensate for this have been observed (e.g.

The hybrid larch (Larix x eurolepis Henry) is a fast growing tree species and was introduced in Sweden for about 50 years ago. The high growth and expected resistance to diseases are probably the main reasons of introducing the tree species into the Swedish forests. The purpose of this thesis was to document the production of hybrid larch planted in the Snogeholm landscape laboratory and to compare the production in the pure hybrid larch stand with the mixture together with pedunculate oak (Quercus robur). The data collection in Snogeholm since the establishment has been carried out by the Swedish University of Agricultural Science (SLU). The fieldwork for the thesis was carried out in 3 stands, containing hybrid larch, pedunculate oak and a mixture of hybrid larch and pedunculate oak, in order to be able to compare the total stand production of the areas. The results show that the total production of hybrid larch in the mixed stand only is 35 % compared with the total production of hybrid larch in the pure stand. Therefore, the hypothesis that the total production of hybrid larch is equal to the planted mixture with pedunculate oak was rejected. The other hypothesis that the total production of a 2 hectare large stand containing a mixture of hybrid larch and pedunculate oak would be greater than the total production of two pure stands of 1 hectare containing hybrid larch and oak each was also rejected. In the studied case the total production was 45 % greater if hybrid larch and pedunculate oak was planted in pure stands. The results from the case-study only indicate that the total production of hybrid larch and oak under the investigated conditions can be higher when planting the two species in pure stands compared with a mixture of the two species.

AimThe aim of this study was to find out whether Motivational Interviewing can affect people to change their behaviour in form of increasing physical activity. What results do studies conducted at healthy adults using Motivational Interviewing with physical activity as an outcome present?MethodTo fulfil the aim of the study we chose a review process. During the research two data-bases were used, PUBMED and CSA. Studies including participants under the age of 18 or studies where the participants suffered from diseases were excluded.

The aim of the study was to get a deeper understanding of how young people think and act when it comes to Contraceptive use, and also if outside factors have an impact on young peoples behaviour in these matters. We looked at our study from an identity and a development perspective. The method was conducted as a qualitative study. There were two groups of 8 young people, aged 16-17. Also 3 professionals that work with young people participated.

According to The National Board of Health and Welfare, about 200 000 elderly persons get some help or support with eating or nutrition problems. This was approximately 2 percent of the population. Older people in sheltered accommodation in community care were not able to manage their own nutrition. The older people were dependent on the food that was offered to them, when and how the food was served. This was a specific responsibility for the nursing staff.

Commonly held dietary guidelines discourage full-fat dairy consumption due its to high levels of saturated fatty acids, which are believed to aversely influence cardiovascular disease risk. Cardiovascular diseases cause more than one third of deaths in the developed world. With dairy often providing a large part of energy and nutrients in Western diets, research into its effects on human health is warranted. Several recent studies have suggested a protective role of dairy in the development of cardiometabolic disease. However, many of these have used imprecise methods of dietary assessment, based on questionnaires or interviews. Biomarkers are emerging as a means of evaluating diet in a more objective way. Currently used dairy fat biomarkers are minor fatty acid constituents of dairy that preferably are unique to dairy and not influenced by endogenous metabolism.

Över hela världen anses huvudlusen (Pediculus humanus capitis) vara den vanligaste ektoparasiten hos människa. I Sverige säljs det ca 100 000 förpackningar med avlusningsmedel varje år, så problemet är uppenbart. Resistensutveckling hos huvudlöss tros vara en viktig orsak till ökningen av dessa parasiter. I maj 2010 kom Läkemedelsverket ut med nya behandlingsrekommendationer där medicintekniska produkter är förstahandsval. Malation respektive permetrin ligger på en tredje respektive fjärdeplats i denna rekommendation.

Background: The majority of the occupational accidents and work-related diseases at Swedish workplaces occur due to poor ergonomics during lifts and transportation of objects. The most common consequence of poor ergonomic conditions is low back pain (LBP) and the risk of developing LBP increases as the mechanical loading on the intervertebral disks grows. This study has investigated the biomechanical loading in the low back during two different types of patient lifts. The first lift (lift A) is developed by Modern Arbetsteknik (MA) and the second lift (lift B) is a common lifting technique among care workers. Objectives: The aim of the study was to identify any advantages or disadvantages with MA?s lift, regarding shear and compression forces in the L5/S1 disc.

COPD (Chronic Obstructive Pulmonary Disease) is one of the most widespread lung diseases today and is a growing cause for suffering and mortality worldwide. It is considered to be the third leading cause of death in the near future. Smoking is the most important risk factor for this disease and about 50% of smokers develop COPD. The purpose of this study was to mediate the experience of not being able to stop smoking described by persons diagnosed with mild or moderate COPD. The study involved five women and five men.

The progress of the health among the elderly has a major meaning for the needs of care, nursing and social services. The health of the elderly has improved but fall and fall accidents are a major problem. Acute diseases, activities and environment risks are often related to fall accidents. The aim of the study was to describe health care staffs? opinions about fall risk and fall prevention.