Transdermal drug delivery, besides painfulinjections with syringes, has long been associatedwith small size particle pharmaceuticals, which candiffuse through the skin. This method of drugadministration has only been applicable on a smallnumber of drugs, where active molecules are smalland delivery time should or can be long.Other drug delivery options are oral administrationand injection with hypodermic Needles (ordinaryhospital syringes). In oral administration thestomach and liver tend to dissolve the drug and theeffect becomes more difficult to anticipate, anddrug delivery rates difficult to control. HypodermicNeedles are used as a mean of drug injectiondirectly into the bloodstream. This method ispainful and risks infection due to tissue damageand skin penetration.One way to get a painless non-damaging techniquewith high delivery rate that still can delivery largemolecules is to manufacture an array of microscopichollow Needles and equip them with a pumping unitthat delivers the correct amount of drugs.This thesis shows the technique and possibility ofmanufacture micromachined Needles using low costtechniques of Ion Track Technology (radiation ofheavy ions creates porous materials), electrolessdeposition (non-current activated wet chemistrymethod of depositing metal) and electroplating.

Blood-borne infectious diseases such as Human Immunodeficiency Virus (HIV)and Hepatitis C Virus (HCV) spread when the addicts share Needles and injecting equipmentwithin contact networks. A quantitative cross-sectional study was conducted in Winnipeg,Canada in December 2003 - September 2004. Through a special questionnaire, respondentswere asked to answer questions about themselves and about their contacts, about relationshipsand how they shared syringes and other injection supplies. Blood tests were used to identifywhether they carried any blood-borne infectious diseases. We selected some variables from theoriginal data set.

Blood-borne infectious diseases such as Human Immunodeficiency Virus (HIV)and Hepatitis C Virus (HCV) spread when the addicts share Needles and injecting equipmentwithin contact networks. A quantitative cross-sectional study was conducted in Winnipeg,Canada in December 2003 - September 2004. Through a special questionnaire, respondentswere asked to answer questions about themselves and about their contacts, about relationshipsand how they shared syringes and other injection supplies. Blood tests were used to identifywhether they carried any blood-borne infectious diseases. We selected some variables from theoriginal data set.

One key factor in silviculture today is sustainability. In order to achieve sustainability it may be important to restore lost nutrients to the forest after clearcutting. In order to calculate the removal, you need to know how much of different elements you will find in different tree compartments. The aim of this study was to investigate if the concentration of elements in different tree compartments of spruce (Picea abies (L.) Karst) were related to the moisture conditions of the site. Five plots at Risfallet (60º 21´ N, 16º 13´ E), was placed along a moisture gradient in a 40- year spruce stand.

Not much is today known about how epiphytic lichens are effected by fire. A considerable part of the fires in Sweden today are prescribed fires for the purpose of environmental conservation. How these fires affect lichens is largely unknown. The aim of this study is to find out how epiphytic fruticose and foliose lichens on Scots pine are affected by fire, and to elucidate the relationship between fire intensity and the survival of lichens and later re-colonization. The study was performed at three locations just outside Umeå in Västerbotten that were burned 5-7 years earlier. In all locations there were larger groups of surviving Scots pines with varying amount of fire-damage in the crown, which enabled a reconstruction of fire intensity.

Not much is today known about how epiphytic lichens are effected by fire. A considerable part of the fires in Sweden today are prescribed fires for the purpose of environmental conservation. How these fires affect lichens is largely unknown. The aim of this study is to find out how epiphytic fruticose and foliose lichens on Scots pine are affected by fire, and to elucidate the relationship between fire intensity and the survival of lichens and later re-colonization. The study was performed at three locations just outside Umeå in Västerbotten that were burned 5-7 years earlier. In all locations there were larger groups of surviving Scots pines with varying amount of fire-damage in the crown, which enabled a reconstruction of fire intensity.

Using biofuels from regeneration cuttings is becoming more common in Sweden. Ash from the combustion of biofuels contains many valuable nutrients and base cations. The Swedish Forest Agency recommends that ash should be recycled to clearings where biofuels have been removed, to avoid future impoverishment of Swedish woodlands. In Jämtland, in northern Sweden, a large quantity of biofuels are taken out from cuttings but ash recycling has not yet been tried. The aim of this thesis was to examine the conditions for ash recycling in Jämtland regarding to soil chemistry and heavy metal content in soil and biofuels.

Background Adolescents and adults suffering from needle phobia have an unreasonable fear of Needles that leads to negative experiences if they do not get the support they need. Negative experiences lead to patients avoiding health care, or these experiences affect important aspects of life. The suffering that a patient experiences may be obvious to some, but others hide it, and then it will be more difficult to detect. The nurse's role is to recognize the suffering and its different reactions in order to alleviate and prevent unnecessary suffering of the patient. AimThe purpose of this study was to describe about young people's and adults' experiences of having needle phobias.

24 years have passed since the Chernobyl accident when radionuclides were spread over largeareas of Europe, including the Scandinavian countries. Today, measurable activities of 137Csare still observed in many Swedish ecosystems.Ants (belonging to the order Hymenoptera) are social insects which collect organic materialfrom a large area around their nests. This study focuses on the 137Cs activity in ant nests andthe cesium accumulation in these nests. The aims were (1) to estimate the 137Cs fall-out in1986, (2) estimate the radiation exposure of ants and (3) find how 137Cs is distributed in an anthill. Seven ant hills (occupied by the species Formica polyctena) were studied near the villageof Hille, situated north of the city of Gävle in central Sweden.

In Scandinavia, capercaillie are often associated with pine trees (Pinus sylvestris) in winter, with pine Needles as the main diet. Few dietary studies have been conducted in Sweden and winter diet is subject to little debate. The interesting thing is that this "pine specialist? is also found in spruce (Picea abies) forest habitats where pine is scarce or unavailable. In many studies outside Sweden (primarily Central Europe) spruce is regularly observed in the winter diet, but I have found no reports on the selection of the diet in spruce forest areas in Sweden.

The demand for renewable energy is increasing in Sweden. This consequently increases the pressure for and willingness to pay for forest fuels. One method to extract forest fuel from suitable commercial thinnings is the "long top method? (LT-method). With this method saw logs and non-delimbed tops are recovered, i.e.

This master thesis has been a pilot study preceding a forthcoming project of a larger scale with the long term objective to separate the direct effect of added nitrogen on soil processes from indirect effects via trees. The aim of this study has been to investigate the allocation of nitrogen following direct injection of liquid solutions into the xylem of 40 year old Norway spruce. The field site is located at Flakaliden (64°07?N, 19°27?E), approximately 60 km northwest of Umeå, Sweden. A total of 18 trees were selected for treatment, equally divided between three treatments, potassium nitrate, glutamine and water (control).

During the past years fire has been identified as an important factor for nature conservation in the forest landscape. To accurately quantify the size of a burnt area is obviously important, but also to quantify the degree of fire damage to the tree canopy. Such data are important for assessing the conservation value, and to support planning and management of the burned area in the future. I have examined how to estimate the status of tree crowns after fire from interpretation of aerial photographs. This is possible because fire changes the structure of tree crowns and this influences the colours in aerial photographs by spectral reflection. Included in the study are four areas, three of which burned in 2005 and one in 2006.

A recommendation for stand treatment of lodgepole pine (Pinus contorta) is, in a scientific point of view, lacking when it comes to harvesting for biomass energy. Within the next decades it is expected that 280 000 hectares of lodgepole pine will have reached thinning age on the domains of Svenska Cellulosa Aktiebolaget (SCA). Due to this the interest has grown rapidly for studying the possibilities of harvesting biofuel assortments already in the first thinning. In this study the distribution of the biomass within lodgepole pine trees has been studied and taken into account for estimating the proportions of harvested assortments when using different methods of thinning. The methods studied were conventional biofuel-harvesting (with delimbed branches gathered separately from the round wood) and thinning with cutting of round wood and long tops (incl.

Bakgrund: Ett nålstick kan ses som ett enkelt ingrepp men för somliga kopplas detta till en stark rädsla och oro. Stickrädsla är vanligt förekommande och kan bero på tidigare negativa erfarenheter. Det är sjuksköterskans ansvar att skapa förutsättningar för patienten att hantera sin stickrädsla och tillgodose patientens grundläggande omvårdnadsbehov. Syfte: Syftet med litteraturstudien var att undersöka stickrädsla hos vuxna patienter och deras erfarenheter av lindrande omvårdnadsåtgärder. Metod: En allmän litteraturstudie baserad på fem kvantitativa artiklar, tre kvalitativa och en där båda metoder tillämpats.