Duchenne Muscular Dystrophy (DMD) is a hereditary X-linked fatal disease that affects 1 in 3500 male births. It is the most common kind of Muscular dystrophy in children and leads to death in the late teens or early 20s for many patients. The mdx mouse is a model of DMD that can be used to investigate experimental therapies. Overexpression of a glycosyltransferase, CT GalNAc, in mdx mice has been demonstrated to prevent the development of Muscular dystrophy. Overexpression of another glycosyltransferase, LARGE, is currently being investigated as a treatment for another group of Muscular dystrophies, the dystroglycanopathies. In this study, we overexpressed LARGE in mdx mice in order to investigate its effect on the development of Muscular dystrophy.

Background: During the last decade physical activity among Swedish adolescents has decreased. Changes regarding physical fitness can also be seen, for instance the cardio respiratory capacity has decreased mainly among young men while Muscular capacity has decreased in both genders. Physical inactivity and impaired physical fitness are both important health related parameters. 18-year olds have fulfilled their physical development and are physically on top of their development, it makes this group interesting to examine. Objective: The aim of this study was to investigate differences between physically active and inactive young men and women, concerning cardio-respiratory fitness, Muscular fitness and balance.

AimThe aim of this study was to investigate if the Swedish elite soccer teams, both males and females, have preventive strategies to reduce the risk of Muscular injuries in the posterior thigh.MethodA survey was created and sent by mail to all (n=28) Swedish elite soccer teams in allsvenskan (both males and females) to be answered by the head of physical exercise within each team. A pilot study regarding the survey was performed by two soccer coaches on elite level and was revised afterwards. The survey was conducted between May through July 2013. In total, 18 soccer teams participated in this survey.Results10 soccer teams did not respond to the survey, which resulted in a drop out of 36%. Preventive strategies to reduce the risk of Muscular injuries in the posterior thigh existed in 16 of the teams.

AbstractTitle: The effect of caffeine on performance during resistance training ?A systematic overviewAuthor: Amanda Jonsson and Erica BenderSupervisor: Mette AxelsenExaminer: Anna WinkvistProgramme: Dietician study programme, 180/240 ECTSType of paper: Examination paper, 15 hpDate: 2015-03-31Background: Products with high content of caffeine has in recent years become popular for optimizing physical performance. Caffeine affects mechanisms in our body which can be beneficial to perform better during exercise, but the theories have not yet been systematically reviewed.Objective: The purpose of this review article, is to examine the acute effect of caffeine intake before strength training on athletic performance with the outcome muscle endurance.Search strategy: A systematic literature search in databases PubMed, Scopus and Cochrane using keywords: ?Caffeine?, ?strength?, ?muscle?, "resistance training", "muscle strength", "strength training", "athletic performance", ?repetitions to failure?, ?Muscular endurance? and ?endurance training?.Selection criteria: Healthy subjects, 16-50 years old, with experience in strength training. Studies with a caffeine intake > 5 mg/kg body weight, which participants performed dynamic strength exercises on a weight > 60% of their 1 RM.

Man has through out times and in all cultures shaped their bodies to the existing bodily ideals. Men's bodily ideals had changed over the last thirty years to a more Muscular, less bodyfat and more V-shaped body. Men and women focus their attention to different body parts. That is why there is a need for a questionnaire witch is specially designed for men. The purpose of this study was to deliniate the body image of men aged 20 to 30 years and to test the reliability of the questionnaire "Mäns kroppsuppfattning".

During the last decade of the twentieth century both ?manhood? and gender studies seems to have undergone changes. With the field of masculinity and the critical studies of men, added as ?subsections? of broader gender studies, new knowledge has been produced to better grasp the production of gender and power relations of patriarchy. During the same decade as the ?metrosexual? first appeared of the urban stage, acts of homophobia and attitudes towards ?manhood? seems to have changed.

Kognitivismen med rötter i analytisk filosofi och logik beskriver tänkande som symbolmanipulation efter logiska regler. Begrepp har sin mening genom att de refererar till objekt och händelser i världen. Embodied cognition (EC) eller kroppsbasserad kognition, med rötter i biologi, fenomenologi och pragmatism ser istället tänkande som ett emergent fenomen som uppstår ur erfarandet av kroppens aktivitet i världen. Begrepps mening har istället sin grund i det sensomotoriska systemet.  Abstrakta begrepp får sin mening via metaforer och metonymer. Likt konstruktivism ser EC lärande som modifiering av tidigare kunskap.

Abstract The core is the center of gravity in our body. Injuries and overload in the joints, is the most common reason for not be able to work in Sweden today. A god strength capacity in the core is important for secure and effective movements, as well for active athletes, as for non athletes. The increased number of employees, who report in sick today, has been correlated with psychological bad health. New methods to deal with mental and physical health problems among people can indicate to the fact that Yoga in the western world has increased its members, due its spiritual and physical recognition in favor of well being.

Sjukdomen Fibromyalgi är vanlig bland kvinnor och innebär symtom som bland annat kronisk och utbredd smärta samt trötthetssyndrom där behandlingen går ut på att lindra symtomen. Fibromyalgi är lågprioriterad inom hälso- och sjukvården och möts fortfarande av en viss skepticism. Detta gör att patienter med denna sjukdom riskerar att känna sig misstrodda och kränkta när de söker hjälp. Därför är det viktigt att sjuksköterskan skapar en bra vårdrelation för att inte kränka patientens värdighet. Fibromyalgi kan leda till en förändrad livsvärld, vilket gör att det är viktigt att få en ökad förståelse för denna patientgrupp.

Skillnaden i muskelstyrka mellan dominant och ickedominant ben hos fotbollspelare hartidigare studerats. Det finns inget enhälligt resultat om vilket ben som är starkast eller om detalls föreligger någon skillnad. Tidigare forskning har utfört mätningarna i sittandeutgångsposition vilket inte stämmer överens med fotbollspelares huvudsakliga aktivitet. Syftetmed uppsatsen var att, hos en grupp fotbollspelare i division ett och två, beskriva och jämföraden maximala muskelstyrkan mellan dominant och ickedominant ben. Datainsamlingenutfördes i en liggande utgångsposition då detta ger liknande muskellängdsförhållandet somvid stående.

Crossfit is a recently developed form of training which is based on a number of functional resistance exercises performed at high intensity, often to the point of Muscular failure. Crossfit has since its introduction 30 years ago, reached vast popularity all around the world, including Sweden. Its practitioners considers Crossfit to be an effective training method for achieving a functional and total trained physique thru improvements in VO2max, muscle strength, endurance, balance and speed. Few scientific studies has been published in the subject which is why this study sets out to examine the effect of Crossfit on VO2max (measured with Åstrands submaximal cyclingtest), maximal strength capacity in lower- and upper body muscles (measured with 1 RM tests in bench press and leg press), rapid strength capacity and strength endurance capacity in upper body muscles (measured with push-up test in 30 seconds) and explosive strength capacity in lower body muscles (measured with sergeant jump test). Five women with an average of 33(±5) years of age all new to Crossfit, performed these tests at two separate occasions with a training period of four weeks consisting of 12(±3,67) Crossfit sessions in between.The result showed a significant improvement in the maximal strength capacity of the leg extension muscles (p=0,025).

Background: During the last decade climbing has become more popular and the numbers of climbers in Sweden have increased considerably. Most common are overuse injuries caused by the great stress and strain climbing creates on different parts of the body. Previous studies show that 75-90% of climbing injuries are localised in the upper extremity. Injuries affecting the lower extremity occur often acute and traumatic. Based on these facts and that the number of climbers constantly grows, it is more likely that the need of care from physiotherapist among climbers will increase.

Selenium (Se) is an essential trace element that is involved in several physiological functions in mammals. Mostly, Se is bound to proteins, many of them with enzymatic functions. A group of seleno-depending enzymes, glutathione peroxidases (GSH-Px?s), are important as antioxidants and protects against free radicals. The activity of GSH-Px is strongly regulated by Se storage in the liver.

?Never!? That was the answer UFC President Dana White gave when asked when women would be seen in the UFC. Two years later the first fight between two women took place and now there?s more than 50 female competitors in the UFC - an organisation that earlier was reserved only for men.?Women will never fight in the UFC? ? A qualitative content analysis of the depiction of women?s MMA in media is a study which focuses on how women?s MMA and Ronda Rousey as an individual athlete are portrayed in american internet based MMA media, with a gender research perspective. This study also investigates how the introduction of the first women?s division in the UFC might have affected the depiction women?s MMA in media.The theoretical framework consists of gender theory concepts such as gender performativity, the man as norm, sports and masculinity.

Av det nötkött som produceras i Sverige råder det stor variation ur kvalitetssynpunkt. Konsumenten kan idag inte garanteras ett nötkött med önskade egenskaper vid varje inköpstillfälle, trots att köttet kommer från samma typ av styckningsdetalj. För att kunna konkurrera med den ökade importen av nötkött och för att kunna erbjuda konsumenten ett nötkött med förbättrad och jämn ätkvalitet finns nu ett gemensamt intresse inom den svenska köttbranschen att bedöma marmoreringsgraden av svenskt nötkött. Köttets marmorering utgörs av det intramuskulära fettet som visat sig ha positiv effekt på köttets sensoriska egenskaper. Studiens syfte var att kartlägga internationella erfarenheter och tillvägagångssätt för marmoreringsbedömning på nötkött samt att belysa det svenska slakteriledets perspektiv inför en ny svensk kvalitetsklassificering avseende nötköttets marmoreringsgrad. Denna studie kan ses som en delstudie i branschorganisationen Svenskt kötts projekt vars mål är att skapa ett system för klassificering av nötkött avseende köttets grad av marmorering för att möta konsumenters önskemål och för att stärka kvaliteten på svenskt nötkött. Utifrån litteraturen har fyra internationella klassificeringssystem studerats där marmoreringsbedömning utgör ett viktigt kvalitetsattribut vid klassificering av slaktkroppen.