Methadone is frequently used as an analgesic drug for dogs although there are very few studies describing the pharmacokinetics of methadone in this species. In man methadone has a long half-life and there are considerable differences in pharmacokinetics between individuals. The dose interval is lengthened when the drug is used fore longer periods of time due to prolonged half-life. Therefore the drug dose must be adjusted individually. The purpose of this study was to study the fundamental pharmacokinetics of methadone in dogs, and to find an optimal drug dosage.

AbstractAim: The aim of this study was to investigate if treatment with ?dry needling? in myofascial triggerpoints (MTrPs) in the rotatorcuff muscles may affect impingement symptoms such as pain during provocative tests, shoulder mobility, and function. The research questions were: Does the value of pain change on the Visual Analog Pain Scale (VAS) between before and after treatment? Do the positive provocative tests for impingement change between before and after treatment? Does the active shoulder mobility change between before and after treatment? Does the self-rated function change between before and after treatment?Method: The study was a prospective randomized intervention study and 19 persons with impingement symptoms (mean ± standard deviation; 58 ± 18 years, and shoulder pain duration 3.9 ± 1.6 months) were randomized into two groups. The groups were tested before, directly after and 3 weeks after treatment.

In metabolism Mg plays an important role because it affects many cellular enzymes in the body. The energy metabolism and protein synthesis are dependent on Mg as an enzyme activator, Mg is also involved in the synthesis of RNA and DNA. Absorption of Mg primarily takes place over the ruminal epithelium in ruminants. The main storage of Mg is in the bones but that can only be reached if the cow is in great need of calcium or phosphorus, it's a hormonal regulated process that induces catabolism of bones. Free and available sources of Mg are found in soft tissues and in the extra cellular fluids that includes cerebrospinal fluids and blood.

SammanfattningSyfte och frågeställningar. Syftet med denna studie var att på äldre personer studera olika fysiologiska parametrar före och efter en period på åtta veckor med styrketräning som utförs tre gånger i veckan. Frågeställningarna var: Hur påverkas statisk och dynamisk maximal styrka i främre lårmuskulaturen av styrketräning? Är det någon skillnad i resultat mellan koncentrisk och excentrisk styrka i lårmuskulaturen före och efter styrketräningsperioden? Är det någon skillnad i förändring mellan benstyrka uppmätt med isokinetisk teknik jämfört med uthållighetsstyrka och ett kort funktionellt benstyrketest? Hur påverkas maximal syreupptagningsförmåga registrerad via submaximalt cykeltest respektive vid pyramidtestet av träningsperioden?Metod. I studien deltog 20 generellt ej påtagligt aktiva män och kvinnor i åldrarna 66-79 år.

Working as a veterinary nurse includes advising animal owners, helping them to make discisions through well-based facts and experience. Preemptive spaying of the healthy bitch brings many advantages and disadvantages. It leads to cessation of gonadal hormone production, and how the exact extent the surgery affects the dog is not yet fully understood. The sex hormones mainly control the reproductive system, but receptors of these hormones are found in many tissues of the body, and have complex relationships with other hormone systems. Spaying decreases the metabolism although the bitch gets an increased appetite, which enhance the risk of obesity, unless the owner restricts food intake.

Whiplash is a bodily injury, where the person that is injured is subjected to force towards the neck, mainly in traffic accidents. Even low speed accidents can cause severe damage due to the complicated muscle and nerve structure of the neck. Symptoms range from neck aches and headaches to numb fingers and this makes the Whiplash injury difficult to diagnose. Whiplash is also a treacherous injury due to the fact that the symptoms can not be objectively verified. The principal symptom of the injury is pain, which is to its nature highly subjective.

Veterinary hospital care and advanced veterinary services are rapidly growing industries. As of January 1, 2010, veterinary nursing became a licensed vocation, the title of veterinary nurse became protected, and the act regulating competence among the professions of the veterinary field was extended. These changes, along with increased demands and expectations from owners, have given rise to greater demands on the staff's qualifications and have increased the need for well-educated staff with expertise in several different areas. The aim of this study was to find out what the licensed veterinary nurse can do in terms of rehabilitation for the hospitalized equine patient suffering from orthopedic injury. This has been carried out through qualitative interviews with veterinary surgeons experienced in treating such patients, and also by reviewing the relevant literature.

The aim of the study was to investigate whether the sedation method had an effect on the screening result for hip dysplasia (HD). Another aspect considered was if the dog?s weight had an impact on the results. This study was a follow up on the results from an earlier study of sedation routines in Swedish dogs. The breeds included in this study were the same as in the earlier one; German shepherd, Bernese mountain dog, Boxer, Newfoundland, Rottweiler, Saint Bernard, Golden and Labrador Retriever.