The aim of this study was to investigate the intraoperative surgical stress response in dogs undergoing ovariohysterectomy and to compare acepromazine and Medetomidine as premedications. 15 dogs diagnosed with pyometra were used in this study. Blood pressure and heart rate were used as parameters to measure surgical stress response. The surgery was divided into four phases. Phase 0 was the period 10 minutes before the skin incision, phase 1 was skin incision and opening of abdomen, phase 2 was manipulation of uterine horns, ligation and transection of mesovarium and phase 3 was ligation of cervix, removal of organs and closing the abdomen. The results showed that phase 2 was the most intense phase of surgical stress, regardless of which premedication the dogs received. When acepromazine and Medetomidine were compared the results showed that within phase 3, all dogs that were given Medetomidine had higher blood pressure compared to dogs that were given acepromazine. The dogs that were given acepromazine had higher heart rate than the dogs that were given Medetomidine in phase 0, phase 2 and phase 3. .

Hip dysplasia is a common, inherited malformation of the coxofemoral joint that eventually leads to osteoarthrosis. Several breeds of dogs are affected and the prevalence varies between different breeds. As part of the effort to reduce the prevalence of hip dysplasia and select dogs suitable for breeding, radiological screening is performed by at least 12 months of age. Before the radiological examination the dog has to be chemically restrained, sedated or anesthetized. The sedation protocol used differs between veterinary clinics. The impact of sedation method of the screening result for hip dysplasia has been studied.

The effects of dexMedetomidine and butorphanol sedation on skin reactivity during intradermal testing in healthy dogs were evaluated. The effects of dexMedetomidine and butorphanol were compared to Medetomidine, a sedative agent having scientific proof of not interfering with skin test reactivity, in a randomised, double blind, cross over study performed on 8 adult dogs. The dogs were sedated with Medetomidine (Domitor vet.®, 0,01 ml kg-1) intravenously, or dexMedetomidine and butorphanol intramuscularly (Dexdomitor vet.®, 0,01 ml kg-1; Dolorex vet., 0,01 ml kg-1) after which they received intradermal injections of positive control solutions (histamine 0,1 mg ml-1, 0,05 mg ml-1, 0,025 mg ml-1), a negative control solution (0,9 % NaCl) and allergen extract (Dermatophagoides farinae, Cladosporium and Artemisia vulgaris). After a wash out period the trial was repeated with a reversed sedation protocol.Skin reactivity (wheal size, induration and erythema) and quality of sedation (immobilization, response to stimuli and injections as well as over all working conditions) were evaluated. The combination of dexMedetomidine and butorphanol provided reliable, good sedation and analgesia without adverse effects.

The aim of the study was to investigate whether the sedation method had an effect on the screening result for hip dysplasia (HD). Another aspect considered was if the dog?s weight had an impact on the results. This study was a follow up on the results from an earlier study of sedation routines in Swedish dogs. The breeds included in this study were the same as in the earlier one; German shepherd, Bernese mountain dog, Boxer, Newfoundland, Rottweiler, Saint Bernard, Golden and Labrador Retriever.

Rabbits carry a high risk of anesthesia related death. This study was part of a project to develop a form of total intravenous anesthesia (TIVA) with minimal effects on cardiac, respiratory and metabolic parameters. In the study, TIVA with sufentanil and midazolam (group TIVA, n=9) was compared with inhalation anesthesia with sevoflurane (group SEVO, n=9) in female rabbits undergoing surgery (ovariehysterectomi). All rabbits were pre-medicated with medetomidin and carprofen before anesthesia induction. Anesthesia was induced with TIVA (2.3 ?g/ ml sufentanil, 0.45 mg/ ml midazolam) at a rate of 4 ml/ kg/ h and the mean induction dose was 0.4 ?g/ kg of sufentanil and 0.1mg/ kg of midazolam.

Dagligen kastreras många honkatter under dissociativ anestesi i Sverige. Dissociativ anestesi anses vara en relativ säker narkos, med minimal påverkan på djuret. Detta gör att det finns en risk att dessa narkoser övervakas i mindre grad än de narkoser där djuren är sövda med gas. Syftet med detta examensarbete var att utvärdera hur dissociativa narkoser av honkatter i samband med ovariehysterektomi övervakas i Sverige samt genom litteraturstudier och en egen studie i mindre skala utvärdera vilken grad av övervakning som är önskvärd vid en dissociativ narkos samt om övervakningen i Sverige idag motsvarar detta. En enkätundersökning skickades under sommaren 2014 ut till 106 djurkliniker i Sverige varav 67 stycken svarade.