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53 Uppsatser om Mammary tumor - Sida 2 av 4
Mekanismer för inaktivering av lipoproteinlipas i 3T3-L1 celler : En studie av hur aktiviteten regleras med Angiopoietin-likt protein 4, Actinomycin D och Tumor Necrosis Factor alpha
Denna studie undersöker hur stressfaktorer påverkar kroppen vid dykning i gruva. Undersökningen genomfördes under en helgs intensivt dykande, för att bestämma lungkapacitet, pulsnivå samt eventuell vätske- och viktförlust hos dykarna. Testerna bestod av vägning, spirometritester och pulsmätningar. Testpersonerna dök mellan ett till tre dyk under helgen. Två av det totala antalet dyk var på 74 meters djup, resterande dyk genomfördes på 36 meters djup.
Virusorsakad uppkomst av juvertumörer/bröstcancer
Bröstcancer/juvertumörer hör till de vanligast förekommande tumörsjukdomarna hos människa, hund och katt, men vad som orsakar uppkomsten av sjukdomen är till största delen okänt. Hos möss har man funnit ett virus ? MMTV ? som orsakande faktor. MMTV, Murine Mammary tumor Virus, är ett retrovirus som kan verka som ett endogent virus eller som exogent agens med möjlighet att nedärvas till avkomman, bland annat via modersmjölk. Infektion sker via aktivering av B-celler, T-celler och andra lymfocyter som tar sig till juvervävnaden och infekterar denna.
Utvärtes behandling av sarkoider på häst med Aldara TM eller Xxterra TM : en jämförande pilotstudie
Sarcoid is the most common tumor in horses all over the world. The sarcoid is a benign, locally invasive, usually fibroblastic proliferative skin neoplasm. Even if the etiology is not completley verified, the epidemiology and clinical behavior suggest a infectious intervention, probably BPV type 1 or type 2. However, it is known that the cause is multifactorial. A genetic prepdispositon has been identified associated to genes within the Major Histocompatibility Complex (MHC), but also to breed, age and perhaps gender.
Utvärtes behandling av sarkoider på häst med Aldara eller Xxterra : en jämförande pilotstudie
Sarcoid is the most common tumor in horses all over the world. The sarcoid is a benign, locally invasive, usually fibroblastic proliferative skin neoplasm. Even if the etiology is not completley verified, the epidemiology and clinical behavior suggest a infectious intervention, probably BPV type 1 or type 2. However, it is known that the cause is multifactorial. A genetic prepdispositon has been identified associated to genes within the Major Histocompatibility Complex (MHC), but also to breed, age and perhaps gender.
En studie av progesteronreceptorer i juvertumörer
I denna studie har förekomst av progesteronreceptorer i olika typer av primära juvertumörer undersökts med hjälp av immunohistokemi. Dessutom har tumörceller från carcinomcellinjen CMT-U27 odlats i olika cellodlingsmedium och exponerats för olika testsubstanser som binder till progesteronreceptorn (progesteron och RU486/mifepristone). Cellernas receptoruttryck och progesteroninnehåll utvärderades med hjälp av ELISA och tumörcellernas viabilitet analyserades med Colorimetric Cell Viability Test.
Av resultaten framgår att samtliga undersökta primära juvertumörer uttryckte progesteronreceptorer. De odlade cellerna hade högre cellviabilitet när de odlades utan fetalt bovint serum (FBS). Efter exponering med progesteron minskade tumörcellernas uttryck av progesteronreceptorer, vilket hämmades av mifepristone.
Dräktighetsdiabetes hos hund :
This article presents a retrospective case study combined with a review of the current literature concerning canine gestational diabetes. A total of 14 cases have been collected from six different clinics in Sweden. There are few previously published reports on canine gestational diabetes.
Gestational diabetes is a disease that rarely occurs in pregnant bitches. The condition is due to the rise of progesterone that occurs during the estrus cycle.
Mastcellens funktion vid försvar mot infektioner
The complexity of the mast cell is becoming more prominent. From being the cell recognized just to contribute to allergic inflammation it is now also associated with wound healing, protection against tumor growth and in recognition and defense against a wide range of pathogens. The location of the mast cell in the barrier between the external and internal environment of the body enables the cell to quickly respond to invading bacteria, virus and parasites. Diarrhea due to Escherichia coli infection, listeriosis, toxoplasmosis, Newcastle disease and bovine respiratory syncytial virus are examples of mast cell activating diseases that can affect animals in, as well as outside, the agricultural sector. Additionally, ticks and tick-borne diseases are of concern.
Fotodynamisk terapi vid behandling av skivepitelskarcinom hos katt :
Photodynamic therapy is a relatively new treatment for superficial squamous cell
carcinoma in cats. There are no publications indicating that the method is being
used in veterinary practice in Sweden at the present time. The method uses the
interaction between a photosensitive agent which has been administered to the
tumor area, light of a wavelength that can be absorbed by the photosensitiser and
the presence of oxygen. In this study photodynamic treatments were performed at
the Queen?s Veterinary School Hopital of Cambridge University between 1998
and 2002.
Prediktion av elproduktion : Modellering av icke reglerbara vattenkraftverk
The main objective of this study is to divide a number of colorectal cancer cases into subgroups based on their molecular features using cluster analysis. The data used is supplied by a research group at Pathology, the Department of Medical Biosciences, Umeå University, and consists, after some preparation, of 455 observations which is a larger data set than many similar studies. The molecular variables that the clustering is based on are CIMP (CpG Island Methylator Phenotype), MSI (Micro Satellite Instability), BRAF- and KRAS-mutations. These are categorical variables and consequently the clustering method used is PAM (Partitioning Around Medoids) which is particularly useful with data on diverse variable level. The final analysis results in four subgroups that are represented by different combinations of attributes on the aforementioned variables.
Prisskillnader mellan privata och publika bolag : En studie om illikviditetsrabatten och dess varierande storlek
The main objective of this study is to divide a number of colorectal cancer cases into subgroups based on their molecular features using cluster analysis. The data used is supplied by a research group at Pathology, the Department of Medical Biosciences, Umeå University, and consists, after some preparation, of 455 observations which is a larger data set than many similar studies. The molecular variables that the clustering is based on are CIMP (CpG Island Methylator Phenotype), MSI (Micro Satellite Instability), BRAF- and KRAS-mutations. These are categorical variables and consequently the clustering method used is PAM (Partitioning Around Medoids) which is particularly useful with data on diverse variable level. The final analysis results in four subgroups that are represented by different combinations of attributes on the aforementioned variables.
Jämlik strokevård : En analys av skillnader mellan patientgrupper avseende vård på strokeenhet, åren 1995-2009
The main objective of this study is to divide a number of colorectal cancer cases into subgroups based on their molecular features using cluster analysis. The data used is supplied by a research group at Pathology, the Department of Medical Biosciences, Umeå University, and consists, after some preparation, of 455 observations which is a larger data set than many similar studies. The molecular variables that the clustering is based on are CIMP (CpG Island Methylator Phenotype), MSI (Micro Satellite Instability), BRAF- and KRAS-mutations. These are categorical variables and consequently the clustering method used is PAM (Partitioning Around Medoids) which is particularly useful with data on diverse variable level. The final analysis results in four subgroups that are represented by different combinations of attributes on the aforementioned variables.
Breast cancer stem cells : evidence and contradictory views
This literature study aims to examine the existence of cancer stem cells in breast cancer. The cancer stem cell theory states that there is a hierarchical organization within a tumour, in which a small subpopulation of the cells can initiate new tumours and maintain tumour growth whilst the bulk of the tumour cannot. These tumour initiating cells have shown to possess many characteristics similar to those of adult stem cells, which is why they are often referred to as cancer stem cells. Both cell types have the capacity of asymmetric division and have shown to possess mechanisms of resistance to both apoptosis and cancer drugs. The cancer stem cell theory elucidates many biological aspects such as the heterogeneity of tumours and the relapse of many cancers after what appeared to be successful treatments.
Molekylär klassificering av tjocktarmscancer : PAM-klusteranalys för identifiering av undergrupper
The main objective of this study is to divide a number of colorectal cancer cases into subgroups based on their molecular features using cluster analysis. The data used is supplied by a research group at Pathology, the Department of Medical Biosciences, Umeå University, and consists, after some preparation, of 455 observations which is a larger data set than many similar studies. The molecular variables that the clustering is based on are CIMP (CpG Island Methylator Phenotype), MSI (Micro Satellite Instability), BRAF- and KRAS-mutations. These are categorical variables and consequently the clustering method used is PAM (Partitioning Around Medoids) which is particularly useful with data on diverse variable level. The final analysis results in four subgroups that are represented by different combinations of attributes on the aforementioned variables.
Omvårdnadsåtgärder för patienter med malign hjärntumör : Ett kunskapsunderlag
Malign hjärntumör är en vanlig sjukdom som ger olika former av symtom beroende på var tumören är lokaliserad och behandlingsformerna kan ge olika komplikationer. Det finns inga tydliga riktlinjer för hur omvårdnaden kring patienten med malign hjärntumör ska bedrivas. Syftet med denna studie var därför att sammanställa ett kunskapsunderlag angående omvårdnadsåtgärder för patienter med malign hjärntumör. Metoden som användes var en litteraturstudie i form av en granskning av vetenskapliga artiklar, vårdprogram, kandidat- och magisteruppsatser och böcker. Resultatet visade vem, hur, var, vad och när information ska ges till patienten.
Immunhistokemisk undersökning av paraffinbäddade celler från pleuravätska som kompletterande underlag för diagnos av cancermetastaser
Background. Immunohistochemistry is a useful method in the differential diagnosis between pleural mesotheliomas and metastatic adenocarcinomas in the pleura. Cytokeratin 20 and 7 have been used successfully as markers in studies determining primary location of adenocarcinomas from metastases. The current study is a complementary research of archived paraffininbedded material of cases with cancer origin. This study contributes a bigger statistical material that may facilitate the search for unknown primary site of adenocarcinoma by identification of metastatic cells in the pleura.Methods.