Introduction: Pain is a subjective experience. People subjected to pain often experience a reducedquality of life. Chronic pain is pain that has been going on for at least threemonths.Problem area: People with chronic pain are subjected to unnecessary suffering and disability. Therefore it is crucial that the nursing staff takes their situation seriously.Purpose: The purpose of the study was to describe the patient's? experiences and apprehensionof living with chronic non-malignant pain, and how this affected their everydaylife.Method: Systematic analysis of 23 depicting articles.

Elakartad katarralfeber är en dödlig sjukdom hos nötkreatur som orsakas av herpesvirus från får eller gnuer. I områden där båda virusvarianterna finns kan man skilja dem åt genom PCR-metoder. Sjukdomen verkar bero på en virusorsakad obalans i immunförsvaret och karaktäriseras av infiltration och ansamling av CD8+ T-lymfocyter. Infekterade celler kan omvandlas till ?large granular lymphocytes? som orsakar celldöd i flera olika vävnader.

Background: Multiple myeloma is a malignant incurable cancer disease associated with severe chronic pain. The nurse has several important roles in the management of patients with multiple myeloma. This study focuses on nurse´s roles including the caring of pain relief.Aim: The aim of this study was to elucidate the nurse?s role in giving care to patients with multiple myeloma and associated chronic pain.Method: This literature study was based on scientific articles.Results: The nurse is in a key position to facilitate ongoing adequate pain and psychosocial assessment of patients with multiple myeloma. The study presents ways of relieving pain and suffering via different ways of caring management.

The RECK gene is a relatively new discovered gene with important implications for cancer research. The research has been primarily concentrated on the human gene with the ultimate aim to identify the invasive characteristics. Up regulated RECK is linked to significantly prolonged survival rates in patients with severe forms of malignancies. RECK is normally expressed in all cells of the body and has an important role in the balance between destructive and constructive features of the extracellular matrix. The RECK protein is a membrane-bound glycoprotein that inhibit matrix metalloproteinases which has the function of breaking down the ECM. There is a significant correlation between RECK gene expression and the formation of new vessels, presumably via the mediation of VEGF which is an important and powerful inducer of angiogenesis.

Syfte: Att belysa sjuksköterskors och patienters upplevelser av vården vid långvarig icke-malign smärta.Metod: Den föreliggande uppsatsen har gjorts som en litteraturstudie där tolv vetenskapliga artiklar har analyserats.Resultat: Sjuksköterskor upplevde smärtbedömningen som en utmaning och ansåg att när de inte trodde på patientens smärtbeskrivning, var det ett hinder för en bra bedömning. Patienterna upplevde att de ofta blev misstrodda av vårdpersonalen och betonade vikten av att bli trodd. Det var viktigt för patienterna att få en diagnos och att hänsyn togs till deras önskan om vad behandlingen skulle resultera i. Patienterna upplevde att deras mål och vårdpersonalens mål med behandlingen inte alltid stämde överens. Sjuksköterskorna upplevde att utbildningen inte förberedde dem för att ta hand om patienter med långvarig smärta och att kunskapen om icke-farmakologiska behandlingsmetoder var bristfällig.

Basal cell carcinoma (BCC) is the most common non-melanoma skin cancer. It can be divided in different subtypes. The most common type is superficial and is most frequently occurring on the trunk and on the face. In severe cases it can be difficult to differentiate basal cell carcinoma from other skin tumors, therefore a skin biopsy is conclusive diagnostic method. In terms of treatment, curettage is a common non-surgical treatment of basal cell carcinoma.

Mast cells have for a long time been known to accumulate around tumors (Maltby et al., 2009). Studies show that they may be important and sometimes essential in tumor angiogenesis, tumor growth and metastasis of tumors (Soucek, et al., 2007; Xiang et al., 2010). In an expression array study (Wensman et al, submitted manuscript) performed on mouse mast cells exposed to tumor conditioned medium, the gene 4-1BB was among the most up-regulated genes compared to control medium. 4-1BB codes for a membrane receptor protein of the tumor necrosis factor superfamily and has been shown to be important in T cell regulation in tumor diseases. This study was performed to investigate if human mast cells up-regulate 4-1BB when they get exposed to tumor conditioned medium.

Thymidine kinase 1 (TK1) is an intracellular enzyme involved in ?the salvage pathway? where the uncomplete parts of DNA are transformed into DNA precursors. The expression of TK1 is cell cykle specific, with the highest level during S-phase when DNA-synthesis is most active. One kind of TK1 is present in serum and an increase in TK1 activity in serum is due to either the level of DNA synthesis in the body or the number of cells dying in a state of replication. This can be used and is used as a marker for prognosis and evaluation of treatment in human patients with leukemia and lymphoma.

Lymphoma is a group of malignant tumour diseases developing in the secondary lymphatic system. These diseases can develop in all organs as lymphocytes are ubiquitously in the body. In connection to mucus membranes we find mucosa-associated lymphoid tissue, MALT, in which lymphoma can spontaneously but slowly develop, mostly at chronic inflammation or at autoimmune diseases. Today these diseases are incureable with the exception of some cases caused by Helicobacter pylori-infection. Antibiotic treatment of these cases can induce remissions.MALT-lymphomas have characteristic histological and molecular properties.

Working as a veterinary nurse includes advising animal owners, helping them to make discisions through well-based facts and experience. Preemptive spaying of the healthy bitch brings many advantages and disadvantages. It leads to cessation of gonadal hormone production, and how the exact extent the surgery affects the dog is not yet fully understood. The sex hormones mainly control the reproductive system, but receptors of these hormones are found in many tissues of the body, and have complex relationships with other hormone systems. Spaying decreases the metabolism although the bitch gets an increased appetite, which enhance the risk of obesity, unless the owner restricts food intake.

The dog has often served as a model animal for humans in scientific studies. This is due to the fact that dogs are susceptible to a wide range of diseases which also affect humans. One example is cancer, a condition that affects dogs as well as owners. Neoplastic diseases account for 18-23 % of all deaths in dogs (Bonnet et al., 2005 and Jagielski et al., 2002). Mammary tumor, or tumor of the breast, is the most common tumor form in intact dogs and women (Im et al., 2013). Mammary tumors originate in the udder, and are classified according to their histological characteristics.