Kolorektal cancer (CRC) är en av de vanligaste cancersjukdomarna i världen med cirka 1 miljon nya detekterade fall per år. Special AT-rich sequence-binding protein1 (SATB1) är ett celltyp-specifikt kärnmatrix-associerat DNA-bindande protein, vilket utgörs av AT-rika DNA sekvenser. Det har tidigare demonstrerats att en annan medlem i SATB-familjen, SATB2, uttrycks på ett vävnadsspecifikt sätt i normal mukosa i nedre mag-tarmkanalen och i CRC. ?-catenin är en intracellulär mediator i Wnt/?-catenin signaleringsvägen, som spelar en viktig roll i kolorektal carcinogenes.

In today?s society, there are many people who suffer from physical pains due to their work situation. To work sitting down by a desk long hours every day is quite normal but this is a problem. People that sit down and work in the same position all day long the whole week will eventually be affected by long-term work injuries.Large multinational companies around the world offer a customer service where they serve customers who have experienced a problem with that company?s products or services.

The purpose of this report is to investigate and compare the difference between stand-thinning machines and strip-road thinning machines, and how they affect the stand on behalf of future growth, theoretical economic result, wind impact, snow pressure and density of stand. The investigation is regarding the first commercial thinning of pine stands, after pre-commercial thinning that was well conducted. The investigation area was located near Katrineholm, Sweden. The measurements that were measured were strength of thinning and amounts of wind throws, snow-breaks and hauling damages. The results that emerged, was that thinning with strip-road machines had a significantly higher strength of thinning over all, as compared with the stand- thinning machines (45 percent versus 30 percent). Comparisons between wind-throws, snow-breaks and hauling damages of the stand could not establish any significant differences between the two methods that were investigated. Conclusions, over all, were that if forest owners want to have more timber volume left for second thinning and final cut of the stand, the forest owners should choose the method with stand-thinning machines. From the point of view of gentle treatment of the stand and ground damages the choice should be the same. However, the method with strip-road thinning machines is the most common and accessible method in Sweden. Most likely it is the most economical way to manage the stand for forest owners in present time. If the method with stand-thinning machines is becoming more common in Sweden, it is suggested for forest owners to consider the stand-thinning method as a candidate for treatment due to economic aspects..

So far, only limited research has been carried out on viruses infecting raspberry, even though the diseases that these viruses cause result in economical losses for raspberry growers. Raspberry ringspot virus (RpRSV) belongs to the family Comoviridae and the genus Nepovirus. Nepoviruses are characterized by their icosahedral virus particles and bipartite genome of single-stranded (+) RNA (RNA-1 and RNA-2). These viruses are transmitted mainly by nematodes of the genus Longidorus, which feed on the roots of plants. RpRSV causes disease in raspberry, grapevine, strawberry and many other plants.

AimThe aim of this study was to map the injury panorama of traumatic injuries related to ice hockey in Sweden 2006-2011. In addition to that the aim was to compare whether there were any gender differences regarding traumatic ice hockey injuries. MethodThe present study was based on data from the Folksam insurance company between 2006 and 2011. The population consisted of ice hockey players in a club affiliated to the Swedish Ice Hockey Federation and that had sustained a traumatic injury related to ice hockey that resulted in medical care and then was reported to Folksam. The results are presented with descriptive statistics such as mean and standard deviation, median range and frequencies. ResultsThe head was the most common injury localization followed by the upper extremity where the shoulder accounted for a high number of injuries. Fracture was the most common type of injury for both male and female players.

The aim of this study is to obtain a deep knowledge about identity creation of preschool child-ren at the age of four to sex with creative pictures and its aesthetic learning processes with childrens perspective as a starting-point. The issues that I have used in this study are how childrens identity creation relates to the aesthetic learning processes in the preschool enviro-ment, how children experience the figuration of their own identity related to other individuals and the enviroment by taking different positions in aesthetic learning processes and how childrens identity creation becomes visible in preschool.In order to explore preschool childrens identity creation in aesthetic learning processes the qualitative research-oriented approach has been implemented with unstructured observations and the informal interview as the methods for data acquiring.This studys theoretical points are sociocultural perspective and symbolic interactionism. Both these theoretical perspectives emphasize the significance of communication, taking different perspectives and learning in an interaction between an individual and enviroment within given sociocultural frames of referens which results in an individuals identity development.Results from the study show that childrens painting is more than an occupation with a picture as a product. Childrens painting is rather a playfull aesthetic expression form and a relation-oriented, dynamic learning process which is related to the enriching of individual self, the consciousness and the creation of meaning within preschools frames of reference.My expectation is that my study will contribute to didactic discussions about childrens iden-tity creation while using aesthetic expression forms..

Tyr ? A historical and comparative study of configurations and formations connected to the Old Norse god Tyr. Klas af Edholm This thesis has two aims. One is a discussion of the history of the study of Old Norse religion and related aspects, centered on how general tendencies within the area of research have affected the interpretations of the god *T?waz/Tyr.

Cows are ruminants and they need fibers in their feed and sufficient eating time to function psychologically and physiologically. Many of our cows don?t get enough forage and too much concentrates, which given in the wrong way may cause health and behavior problems. Too much concentrates at once makes the pH in the rumen sink and this may cause decreased fiber utilization since the microbes in the rumen are negatively affected by this. The cow may also get serious problems such as laminitis and abomasal dislocation.

Silage is today a common feed for different animals. A general way of storing silage is in bunker silos covered with polyethylene film. The covering and uncovering is labour intensive and it is often difficult to get the silo properly sealed. Because of these reasons many American farmers leave their silos uncovered and accept the losses accompanied. One purpose of this study was therefore to examine if it sometimes can be justified to leave bunker silos uncovered.

Pulsatilla vernalis is one of several endangered plant species that benefit from wildfires and small scale disturbance events that repel competing vegetation and create open patches in the vegetation cover. Previous studies argue that Pulsatilla vernalis is decreasing in numbers due to vegetation changes associated with the decrease in wildfires, forest grazing and changes in forest management. In this study, 17 populations of P. vernalis were inventoried in order to examine if soil and/or vegetation structures affect the population structure of P. vernalis (i.e.

Abstract Tripeptidyl-peptidase II (TPPII), is present in most eukaryotic cells. It cuts tripeptides from the N-terminus of peptides and is especially important for degrading peptides longer than 15 amino acids. TPPII also tailors long peptides into suitable substrates for the enzymes which transport and produce the peptides that MHC I present. Increased levels of TPPII have also been found in certain cancer cells, thus it is of interest to determine if TPPII could be used as a tumour marker.The aim of this study was to optimise and evaluate 3 different methods for quantifying TPPII. Western blot, enzyme-linked immunosorbent assay (ELISA) and fluorophore-linked immunosorbent assay (FLISA) protocols were optimised regarding incubation times and antibody dilutions.

Denna uppsatssyfte var att ta reda på vilken kännedom som finns om de svenskanäringsrekommendationerna hos människor på ett antal svenska arbetsplatser. Syftet har även inne-fattat att ta reda på huruvida man använder sig av denna kännedom eller inte.Metod: Enkvantitativ ansats i en tvärsnittsstudie har använts i denna undersökning och hundratio enkäter har blivit besvarade. Dessa enkäter har analyserats både kvantitativt och kvalitativt.Resultatetvisade att majoriteten av respondenterna inte kände till de svenska näringsrekom-mendationerna. Majoriteten var också omedvetna om hur den procentuella energifördelningen såg ut. Jämförbart med tidigare studier så underskattade männen rekommendationerna för grönsaker medan kvinnorna hade mer kännedom om rekommendationerna som helhet.

Insomnia is getting more prevalent with age, both because of natural changes in the sleep pattern and because of increased morbidity. It can cause dysfunctioning and sedation during the day. Therefore it is often treated with hypnotics. It is possible though that hypnotics can cause daytime sleepiness as well, not to mention increased risk of falling and fractures because of sedation and prolonged reaction time. Benzodiazepines and benzodiazepine related drugs, the subjects of this study, are commonly used as hypnotics.

The object of this explorative theoretical study is to compare similarities in three perspectives for evaluation of credibility. The perspectives are the historical method source-criticism, cognitive authority and domain analysis. These perspectives, regarded as intellectual tools for critical thinking in a process of information seeking, by asking questions about credibility related to the social and theoretical context of the intellectual background, can give support in articulating which documents that gives a specific and essential answer to a question. In this sense credibility is seen as a qualitative aspect of relevance. Patrick Wilson argues that we can attain some critical independence towards cognitive authorities and the literature by investigating the social and theoretical topography of a field.

Today's urban centers become denser, which contributes to higher demands on sound and noise. It is therefore highly relevant to build homes with good sound environment while maintaining living space. This thesis aimed to reduce the current concrete walls and see how the mass law affects the reduction index value and flanking transmissions. Handmade calculations were calculated according to the Swedish standard SS-EN 21354-1, where only air sound was calculated.Calculations we­­­re performed on wall elements with different weights and thicknesses, and compared with results from Bastian.In Bastian calculations of flanking transmissions were also made, this was made to see the impact of the flanking transmission when changing the mass per unit area. Mass law's impact was examined by flanking transmission and the result shows that they are not affected as long as the ratio between the thickness and the density remains the same.A questionnaire survey was conducted to determine the actual sound experience; this questionnaire was conducted on three concrete buildings in Växjö.