Inclusion body disease (IBD) affecting boas and pythons is a serious and common disease. Boas can be clinically healthy carriers, which makes control of the disease difficult. The causative agent has not yet been confidently identified, and therefore there are no serodiagnostic tests available. Today, histopathologic examination of tissue biopsies is the recommended antemortem diagnostic method, but there are several disadvantages. The objective of this study was to compare the sensitivity of two diagnostic methods ? Liver biopsies and blood smears, and to evaluate ultrasoundguided needle biopsy of the Liver.

Sahlgrenska Academyat University of GothenburgDepartment of Internal Medicine and Clinical NutritionAbstractTitle: BCAA supplementation in patients undergoing resection for Liver cancerAuthor: Mikael Semaan and Viktor SjölingSupervisor: Fredrik BertzExaminer: Frode SlindeProgramme: Dietician study programme, 180/240 ECTSType of paper: Examination paper, 15 hpDate: April 10, 2013BackgroundLiver cancer is the fifth most common cancer worldwide and the third largest to cause death. Protein-energy malnutrition is common in patients with Liver disease and they often suffer from changes in the hepatic metabolism of nutrients and other substances. There is a basis for recommending BCAA supplementation in other certain Liver diseases. Given the similar clinical picture of Liver cancer surgery, it is possible that supplementation of BCAA can be beneficial for these patients as well.ObjectiveThe aim was to study the scientific basis for the effect of branched chain amino acid (BCAA) supplementation in Liver cancer patients. Can it improve their recovery in terms of nutritional status and albumin levels, and does it changes the duration of hospital stay, after surgery?Search strategyFive extensive searches were performed on PubMed and Cochrane after appropriate study material.

Perfluoroalkyl substances (PFASs) are ubiquitous in the environment today and they have been detected even in remote areas such as the Arctic. PFASs can be transported by the atmosphere and ocean currents but the transport mechanism is not fully understood. PFASs may be harmful to organisms due to their persistence in the environment, bio-accumulation potential and toxicity. Studies have shown that PFASs can cause adverse effects on the metabolism as well as the endocrine- and reproduction systems in organisms. In this study, PFASs were investigated in glaucous gull (Larus hyperboreus) (n=5) and black guillemot (Cepphus grylle) (n=4) from Svalbard.

There is convincing research which shows that the enzyme alkaline phosphatase (ALP) has a central role in the mineralization of bone, more precisely that its catalytic activity is needed in the process. ALP is found on the surface of matrix vesicles where the mineral is formed. One theory about the function of the enzyme is that it binds to fibrous collagen in the bone and thereby incorporating the mineral into the bone. The purpose of this study is to establish whether ALP binds to collagen. If this is the case, more elaborate studies around this will be performed.

Mussel meal is a potential source of protein, with a good composition of amino acids, for laying hens and broiler chickens, and may replace the use of fish meal in organic poultry production. Lead and cadmium are heavy metals which occur in the environment and can be accumulated in mussels. When poultry are exposed to heavy metals, the metals are absorbed in the small intestine and distributed in the body in the form of ions, complexes or bound to proteins. In poultry, lead accumulates in bone tissue, Liver and kidneys, while cadmium accumulates in Liver and kidneys. Generally very low concentrations of these heavy metals occur in muscles of broilers which have been exposed to feed contaminated with cadmium or lead.

Since several lifestyle diseases are associated with obesity much research is carried out within the area. Researchers have found that oxidation of fatty acids within the body?s cells may give rise to peripheral signals which regulate food intake, but it is still unclear where such a mechanism takes place. Although much evidence suggests that it is the hepatocytes in the Liver that send signals regulating food intake, some researchers have begun to question this theory. Instead they argue that the mechanism takes place within the enterocytes since they are well localised in the gut for such assignment.

Bakgrund: Levercirros är ett sjukdomstillstånd som har hög mortalitet om inte en levertransplantation genomförs. Väntelistan till transplantation är lång samtidigt som organbehovet ökar. Syfte: Syftet med studien är att beskriva patientens upplevelser och livskvalitet i väntan på en levertransplantation. Metod: En litteraturöversikt valdes där 9 vetenskapliga artiklar granskades och analyserades enligt Fribergs modell (2006). Resultat: Beskedet om att bli uppsatt på väntelista präglades av både positiva och negativa känslor; glädje, lättnad, oro samt tveksamhet.

To date, the genus Helicobacter consist of 26 different species and even more species are yet to be characterized. Helicobacter has been detected in connection with diseases in the Liver and pancreas in humans and animals. Helicobacter spp. are gram negative, curved, S-shaped or spiral shaped bacteria. They are microaerophilic and have flagella that make them motile. Helicobacter, present in the gastric mucosa neutralize the gastric acid through production of urease that hydrolyses urea to ammonia and bicarbonate.

Clopidogrel is an antiplatelet substance that prevents blood coagulation in the arteries. It is an inactive pro drug that becomes activated after first-pass metabolism by the Liver. The active metabolite of clopidogrel is 2-oxoclopidogrel, which is unstable therefore pharmacokinetic data is obtained by measuring the inactive metabolite clopidogrel acid in plasma. Clopidogrel is taken orally in tablet form. The aim of this project was to develop a LC-MS/MS method for quantification of clopidogrel and its metabolite in plasma. The method has been developed by optimizing the sample preparation.

An inflammatory reaction is induced after release of proinflammatory mediators such asinterleukin 1 and 6 and tumour necrosis factor ?. These mediators stimulate the Liver tosuppress the syntheses of albumin and endure the syntheses of acute phase protein forinstance C-reactive protein. The aim of this paper was to perform a method validation on animmune turbidimetric assay to quantify C-reactive protein in canine serum at the laboratory atSkara Animals Hospital, Skara, Sweden. The validation involved evaluation of the assaylinearity, precision, stability and recovery.The method was proved to be linear for both TruLab control and Medinor control.

The purpose of my study is that I have examined children age 4 years and 5 years of their perceptions about the body's internal organs, and if they know where they are sitting in the body, and what their perception of organ systems. I have compared their perceptions and thoughts about the internal organs, to see their similarities and differences it is about childrens perceptions and thoughts dependent if they is 4-respektive 5- years old.The results that I got from my examination was that they showed me a big variety by their earlier perception about the organs. Some had knowledge of the name, some had of the function and some of the place of the organ brain, heart, lungs, stomach, Liver and intestines. All these knowledge about the organs was a variety on and you could see similarities and differences in the different ages. One example about a different is that it was a four year old child that could the name of the stomach and the stomach function while there was three five years old children that could the brains name, function and place..

Sjuksköterskan bör ha kunskap om begreppet livskvalitet för att kunna bemöta patienter som genomgått en levertransplantation, då den upplevda livskvalitén är betydelsefull för patienterna. Syftet var att beskriva livskvalitet hos patienter som genomgått en levertransplantation. Studien är genomförd som en litteraturstudie där 12 vetenskapliga artiklar har granskats. Resultatet visar att den upplevda livskvalitén hos levertransplanterade patienter är relativt god men det finns delar av livskvalitén som påverkas negativt efter levertransplantationen. Livskvalitén påverkas av fysiska, psykiska och sociala aspekter.

Det finns många olika typer av bromerade flamskyddsmedel. De är alla stabila i miljön men graden av toxicitet och bioackumulering varierar. Att bromerade flamskyddsmedel är endokrinstörande är känt men min hypotes är att de även är neurotoxiska och att de kan orsaka neurologiska störningar hos människa. Människor exponeras för bromerade flamskyddsmedel via damm och föda. Barn och foster som är känsligare än vuxna kan även exponeras via modersmjölk respektive placenta. Barn har högre serumkoncentrationer av bromerade flamskyddsmedel än vuxna.

Ultrasound is still a relatively new method for the diagnosis of abdominal conditions in cattle. The objective of this study is to evaluate ultrasound as a diagnostic tool for the common diseases affecting high-producing dairy cattle, for example traumatic reticuloperitonitis, right- and left displacement of the abomasum, fatty Liver, wound infections and abscesses. This paper is a combined litterature study and a report of the results from ultrasound examinations of bovine patients at the ruminant clinic at the Swedish University of Agricultural Sciences. The study includes two healthy cows from the ruminant clinic, and seven patients with abdominal related diseases. The examinations were made with a 2-6 MHz curvilinear transducer and both the right and left sides of the abdomen were scanned.

Equine cutaneous melanomas arise much more often in horses with a grey coat color than in horses of other colors. Some scientists have in different studies come to the conclusion that the melanomas are neoplasms which can be classified by examining their histological and macroscopic features. The more defined and demarcated a tumor is, the more benign it tends to be. Other scientists believe that the skin lesions are the result of a pigmentation disorder that is linked to the greying of the coat color. According to this theory, the lesions are not malignant although they have the ability to metastasize.